George W. Bush, the Party System, and American Federalism

George W. Bush's presidency presents two major puzzles. TheRepublican Party has traditionally stood for "limited government,"but Bush's principal legacy for federalism is centralizationof power in the federal government and the executive branch.Most modern presidents have neglected their partisan duties,but Bush has been a uniquely vigorous party leader. Here, weshow that Bush's puzzling lack of attention to federalism issuesis in large part the result of his efforts to strengthen theRepublican Party to cope with the political and electoral challengescharacteristic of the contemporary political context. We explainwhy the Bush administration's strategy for redressing the Republicanparty's shortcomings has presupposed the deprecation of federalism,and consider the implications of our argument for the developmentof federal arrangements.     

Changes in the ratio of collagen type I and III in the interlobular interstitium of the lung in sudden infant death--a pilot study

In a blind study the interlobular interstitial connective tissue in paraffin embedded lung sections from 45 autopsy cases aged under 2 years (23 SIDS and 22 Non-SIDS) were investigated with the aim of determining the collagen type I:type III ratio by means of polarimetric evaluation. Sections were stained with Resorcin-Fuchsin for elastin fibres, Celestine Blue/Mayer's Haematoxylin for nuclear details and with Solophenyl Red 3 BL in saturated picric acid solution for the differential staining of type I and type III collagen fibres for polarization microscopy. The type I fibres were orange and the type III fibres green in colour. The spectral distribution of the coloured polarized light from the sections was determined and peaks were evident at the wavelengths 590 nm for the orange coloured light of type I and 490 nm for the green coloured light of type III collagen. With corresponding filtres the intensities of the orange and green emissions were separately measured at several points adjacent to lymphatic vessels. The ratio collagen I/III, deduced from the ratio of the intensities of orange to green light, was significantly higher in the SIDS-group than in the Non-SIDS-group (a = 0.001) due to the increase in the amount of collagen type I and could indicate an insiduous fibrosis resulting from lymphostasis.