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71.
Jon BingAuthor Vitae 《Computer Law & Security Report》2009,25(1):89-96
As a contribution to this special issue of CLSR, Jon Bing offers a unique wartime account of one of the earliest attempts to prevent ‘online processing’ of personal data by the occupying authorities for oppressive purposes. 相似文献
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Chang Hua Wong Seok Hwee Koo George Qiongze She Paul Chui Edmund Jon Deoon Lee 《Forensic Science International Supplement Series》2009,192(1-3):53-55
We analyzed the coding regions of the cardiac calcium-handling genes, ryanodine receptor 2 (RyR2) and calsequestrin 2 (CASQ2) for genetic variants in a healthy Chinese population (n = 95) and in a cohort of 28 sudden unexplained death victims. Mutations in RyR2 and CASQ2 have been shown to alter calcium homeostasis during excitation–contraction coupling and predispose individuals to fatal cardiac arrhythmias. The genetic screening was accomplished by denaturing high-performance liquid chromatography and DNA sequencing methods. Genetic analysis revealed the following non-synonymous genetic variations: two reported RyR2 polymorphisms; 5654G>A (G1885E) and 5656G>A (G1886S), two reported CASQ2 polymorphisms; 196A>G (T66A) and 226G>A (V76M) and one novel CASQ2 mutation; 529G>C (E177Q). The functional significance of the novel CASQ2 mutation has not been evaluated and characterized. This study shows that multiple genetic variations of the RyR2 and CASQ2 genes exist in the two study populations. The inter-individual genetic variability may underlie the different susceptibility of individuals to developing ventricular tachycardia. The research results will be valuable for which future work involving clinical and forensic samples can be based upon to distinguish potential disease-associated mutations from common polymorphisms. 相似文献
73.
Shackelford TK Weekes-Shackelford VA Beasley SL 《Journal of interpersonal violence》2008,23(5):589-599
Filicide (the killing of a child by a parent) followed by the offender's suicide is a tragic but, fortunately, rare event. The contexts and circumstances surrounding filicide-suicide may provide insight into parental psychology. The authors test several hypotheses about filicide-suicide using a database including incident-level information on 11,018 Chicago homicides during 1870-1930. The results provide some support for the hypothesis of differential risk of suicide following filicide by genetic parents and stepparents and replicate previous research indicating that filicides with multiple victims are more likely to end in the offender's suicide than are filicides with a single victim; parents are more likely to commit suicide following the filicide of an older child than of a younger child; and older parents, relative to younger parents, are more likely to commit suicide following filicide. The discussion situates these results within the existing literature and highlights important directions for future research. 相似文献
74.
Jon Rubin 《Feminist Legal Studies》2001,9(1):75-83
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This study employs twenty-three years of federal, state, andinstitutional student-aid data to investigate the effects offederal grants to students on the behavior of higher educationinstitutions. Unlike previous studies, this research differentiatesbetween federal-aid programs according to whether a federalprogram follows "redivision federalism" or "cooperative federalism"concepts. Pell grants, exemplifying the former, appear highlyfungible and inversely related to institutional grants to students,while campus-based federal programs, exemplifying "cooperativefederalism, " appear less fungible and positively associatedwith institutional grants. The results also suggest that grantsto students are more important to higher education opportunitythan indicated by some previous research. 相似文献