Three commercially available integrated rapid DNA instruments were tested as a part of a rapid DNA maturity assessment in July of 2018. The assessment was conducted with sets of blinded single-source reference samples provided to participants for testing on the individual rapid platforms within their laboratories. The data were returned to the National Institute of Standards and Technology (NIST) for review and analysis. Both FBI-defined automated review (Rapid DNA Analysis) and manual review (Modified Rapid DNA Analysis) of the datasets were conducted to assess the success of genotyping the 20 Combined DNA Index System (CODIS) core STR loci and full profiles generated by the instruments. Genotype results from the multiple platforms, participating laboratories, and STR typing chemistries were combined into a single analysis. The Rapid DNA Analysis resulted in a success rate of 80% for full profiles (85% for the 20 CODIS core loci) with automated analysis. Modified Rapid DNA Analysis resulted in a success rate of 90% for both the CODIS 20 core loci and full profiles (all attempted loci per chemistry). An analysis of the peak height ratios demonstrated that 95% of all heterozygous alleles were above 59% heterozygote balance. For base-pair sizing precision, the precision was below the standard 0.5 bp deviation for both the ANDE 6C System and the RapidHIT 200. 相似文献
Critics of neoliberalism argue that so-called meritocratic and identity-neutral social policies and political positions actually reinforce and exacerbate intersecting inequalities, namely racism, sexism, heterosexism, classism, and ethnocentrism/xenophobia. The purpose of these studies was to develop and initially validate a scale of neoliberal attitudes from a wide range of existing instruments that reflect anti-neoliberal theory. A series of three studies resulted in a 25-item instrument—the Anti-Neoliberal Attitudes Scale (ANAS)—that exhibits initial evidence of construct validity, internal consistency, and test–retest reliability. Exploratory factor analysis with students from two universities revealed a four-factor structure of Racism and Sexism Awareness, Communitarian Values, Multicultural Ideology, and Inequality Consciousness. However, a confirmatory factor analysis with an independent sample of undergraduate students suggests a bifactor model in which the general factor explains most of the variance and that the instrument should be treated as a single scale, rather than independent subscales. Significant correlations with measures of right-wing authoritarianism and social dominance orientation suggest convergent validity. Temporal stability was established via a test–retest analysis in an independent sample of undergraduate students. Finally, responses from a sample of MTurk workers provided evidence of the ANAS’s incremental validity when compared to an existing measure of neoliberal beliefs. Implications for future empirical work on the psychological dimensions of neoliberalism are discussed.
Participants (n = 36) with consistent Pre-conformist ego development levels during multiple adolescent assessments were studied to determine
whether and how their ego levels had changed at age 25. Those (n = 12) whose ego levels remained at the Pre-conformist level were assigned to a life-course-persistent profound ego development arrest trajectory group; those (n = 24) whose ego levels reached the Conformist or Post-conformist level at age 25 were assigned to an adolescence-limited profound ego development arrest trajectory group. Analysis of predictors and age 25 correlates of group membership revealed that selected age 14 family interaction
behaviors differentiated the two groups. At age 25, members of the adolescence-limited group showed superior performance on
several measures of interpersonal and intrapersonal functioning.
The broader context of relational aggression in adolescent romantic relationships was assessed by considering the ways such
aggression emerged from prior experiences of peer pressure and was linked to concurrent difficulties in psychosocial functioning.
Longitudinal, multi-reporter data were obtained from 97 adolescents and their best friends at age 15 and from adolescents
and their romantic partners at age 18. Teens’ relational aggression and romantic partners’ victimization were predicted from
levels of best friends’ pressuring behaviors toward teens in an observed interaction as well as from best friends’ ratings
of how much pressure teens experienced from their peer group. Romantic partner relational aggression and teen victimization
were predicted by pressure from teens’ peer group only. Adolescents’ romantic relational aggression and victimization were
also associated with elevated levels of depressive symptoms and increased alcohol use. Results are discussed in terms of the
connection of relational aggression in romantic relationships to the broader task of establishing autonomy with peers in psychosocial
development.
This article describes trends in suicide attempt visits to emergency departments in the United States (US). Data were obtained from the National Hospital Ambulatory Medical Care Survey using mental-health-related ICD-9-CM, E and V codes, and mental-health reasons for visit. From 1992 to 2001, mental-health-related visits increased 27.5% from 17.1 to 23.6 per 1000 (p < .001). Emergency Department (ED) visits for suicide attempt and self injury increased by 47%, from 0.8 to 1.5 visits per 1000 US population (p(trend) = .04). Suicide-attempt-related visits increased significantly among males over the decade and among females from 1992/1993 to 1998/1999. Suicide attempt visits increased in non-Hispanic whites, patients under 15 years or those between 50-69 years of age, and the privately insured. Hospitalization rates for suicide attempt-related ED visits declined from 49% to 32% between 1992 and 2001 (p = .04). Suicide attempt-related visits increased significantly in urban areas, but in rural areas suicide attempt visits stayed relatively constant, despite significant rural decreases in mental-health related visits overall. Ten-year regional increases in suicide attempt-related visits were significant for the West and Northeast only. US emergency departments have witnessed increasing rates of ED visits for suicide attempts during a decade of significant reciprocal decreases in postattempt hospitalization. Emergency departments are increasingly important sites for identifying, assessing and treating individuals with suicidal behavior. 相似文献
This paper seeks to explore some of the security and conflict dimensions of the China-Africa relationship, illustrating what the challenges are, why they are important and what has been done to meet them. Section one provides a brief overview of the different manifestations of conflict and insecurity on the African continent, highlighting that Small Arms and Light Weapons (SALW) proliferation is a problem that links them all. Section two explores the reasons why China has a stake in the peace and security o... 相似文献
Possessing social power leads to approach-related affect and behavior, whereas lacking power leads to inhibition (Keltner,
Gruenfeld, & Anderson, Psychol Rev 110:265–284, 2003). However, such effects should be moderated by whether an explanation is given for these power differences. Participants
were assigned to a low-power or high-power role and then interacted with a confederate in the opposite role. Participants
were told these role assignments were made for legitimate (expertise) or illegitimate (nepotism) reasons, or were given no
explanation. High-power participants showed more approach-related affect and behavior and reported less dissonance than low-power
participants, but many of these effects were moderated by the presence versus absence of an explanation. When no explanation
for power differences was provided, high-power participants exhibited more approach-related behavior than low-power participants
but also felt more guilt and unease. Implications for system justification theory and the literature on social power are discussed. 相似文献