Quantitation of Synthetic Cannabinoids in Plant Materials Using High Performance Liquid Chromatography with UV Detection (Validated Method)

Plant based products laced with synthetic cannabinoids have become popular substances of abuse over the last decade. Quantitative analysis for synthetic cannabinoid content in the laced materials is necessary for health hazard assessments addressing overall exposure and toxicity when the products are smoked. A validated, broadly applicable HPLC‐UV method for the determination of synthetic cannabinoids in plant materials is presented, using acetonitrile extraction and separation on a commercial phenylhexyl stationary phase. UV detection provides excellent sensitivity with limits of quantitation (LOQs) less than 10 μg/g for many cannabinoids. The method was validated for several structural classes (dibenzopyrans, cyclohexylphenols, naphthoylindoles, benzoylindoles, phenylacetylindoles, tetramethylcyclopropylindoles) based on spike recovery experiments in multiple plant materials over a wide cannabinoid contents range (0.1–81 mg/g). Average recovery across 32 cannabinoids was 94% for marshmallow leaf, 95% for damiana leaf, and 92% for mullein leaf. The method was applied to a series of case‐related products with determined amounts ranging from 0.2 to >100 mg/g.     

Using Game of Thrones to Teach International Relations

Despite the known benefits of long-term, game-based simulations they remain underutilized in Political Science classrooms. Simulations used are typically designed to reinforce a concept and are short-lived, lasting one or two class sessions; rarely are entire courses designed around a single simulation. Creating real-world conditions in which students operate often requires the development of distinct cultures and shared experiences that only long-term interactions can generate. These long-term interactions create a community where the past interactions of players matter when making decisions about future action. Long-term role-playing also gives students a forum to fully immerse themselves in the material resulting in deeper content comprehension. This article presents a framework for using a long-term, game-based simulation based on the popular television show Game of Thrones. The simulation uses an active learning approach to help students understand a variety of topics related to International Relations and related fields. The article concludes with a discussion on how the simulation can be modified to fit a variety of non-Political Science courses as well as provides the framework for an experimental design to test the effectiveness of the simulation.     

Exploring the Intersection of Theory and Practice of Arts for Peacebuilding

A rising number of public and nongovernmental organisation (NGO) leaders are employing the arts in efforts aimed at encouraging social change. Meanwhile, scholars have offered a number of theories concerning the character of political agency and its exercise, and contended that effective use of the arts may result in individual and group epistemic change. Far fewer analysts, however, have married such theorisations of aesthetics with empirical investigations of how professionals actually use the arts to promote such shifts. This article addresses this concern by studying the strategies adopted by two international nongovernmental organisations (INGOs), American Voices and Bond Street Theatre, that have worked to encourage peace through music and theatre-making in light of changing conceptions of agency and the power of aesthetics to stimulate its exercise. We outline the approaches these NGOs adopt to do so and the mechanisms by which their leaders believe their work catalyses changes in values at the individual and community levels. We argue that understanding these dynamics more thoroughly and in light of conceptions of agency and aesthetics leads to a stronger theorisation of whether and how arts-based peacebuilding efforts can lead to sustainable community cultural change.     

Steroid Use and School Violence,School Violent Victimization,and Suicidal Ideation Among Adolescents

School violence, school violent victimization, and suicidal ideation among adolescents are serious public health concerns. This pilot study investigated the influence of steroid use on problem behaviors. Secondary data analyses of the 2014 PRIDE Questionnaire were performed based on information collected from 38,414 high school adolescents. Results indicated high rates of school violence, school violent victimization, and suicidal ideation. Steroid use was directly related to all three problem behaviors. Results varied based on sex, race, grade level, and ethnicity. Health professionals, schools, and prevention specialists may benefit from the findings of this study. Examination of other factors related to steroid use in relation to the aforementioned problem behaviors is imperative.     

Analysis of 13 tetrameric short tandem repeat loci in a population of Tuscany (Central Italy) performed by means of an automated infrared sequencer

Allele frequencies for the 13 STRs of the Combined DNA Index System (CODIS) core were obtained from a sample of 188 unrelated individuals living in the area of Florence, Prato and Pistoia (Tuscany, Central Italy).     

Human Rights in the United States: The Unfinished Story of Political Prisoners and Cointelpro

For many years, black nationalists have tried to reopen the investigation into the FBI's COINTELPRO (COunter-INTELligence PROgram), which served to disrupt and destroy the black liberation movement and other progressive movements in the US. On September 14, 2000 in Washington, DC, Congressional Representative Cynthia McKinney (D-Georgia) convened a "brain trust" on this subject as part of the Congressional Black Caucus' Legislative Conference, a yearly series of forums and panel discussions on issues of importance to the communities represented by the Caucus. The title of the McKinney panel was "Human Rights in the United States: The Unfinished Story of Political Prisoners/Victims of COINTELPRO." Six panelists presented information on the history of COINTELPRO and its relevance to the cases of the approximately 100 + political prisoners in US custody at this moment. Some of these prisoners have served 30 or more years; all have exceedingly long sentences. While the US government denies that it holds any political prisoners, the facts of the cases—and the connection of many cases to COINTELPRO operations—indicate otherwise. Several current and past political prisoners, most notably Jalil Muntaqim (Anthony Bottom) and Dr. Mutulu Shakur, along with released political prisoner Herman Ferguson, have consistently urged that the illegalities committed under COINTELPRO be examined further, and that compensation be made to the victims of these acts. The panel presentations excerpted below all point to the necessity of such an examination—and of releasing all of the US-held political prisoners in order to redress the crimes committed against progressive political movements under the aegis of COINTELPRO and other FBI counterintelligence programs. The significance of this issue to the community was illustrated by the tremendous crowd that gathered and participated in the discussion following the panel.