An exploration of the legal and socio-ethical implications of predictive genetic testing of children

This article explores the current position in relation to predictive genetic testing of children, highlighting some of the legal and socio-ethical issues and complexities that such testing presents. It evaluates the existing regulatory framework for predictive genetic testing of children in Australia, including the possible role of the Family Court in protecting children from inappropriate testing, and suggests that introducing a more interventionist approach would create its own difficulties. The article also considers a particular issue arising in the context of predictive genetic testing of children which the ALRC/AHEC inquiry canvassed concerning disclosure obligations to insurers. The article argues that creating an exception to established principles of disclosure would mitigate the impact of predictive genetic testing of children and would be consistent with international instruments which seek to protect against unfair genetic discrimination.     

Adolescent women's developing identity: A study of self-definition in the context of family relationships

This study generated adolescent women's perception of their identity in relation to family members spanning three generations and related these perceived relationships to their sex-role orientation. Subjects were 20 firstborn university women from intact families. The methodology used multiple sources of information, including open-ended interviewing procedures, rating scales, and standard research measures of sex-role identity. Significantly more constructs empirically differentiated family by generation than by sex. Congruence of young women with both the parent and grandparent generation, relative number of masculine stereotypes produced, and personality traits of males and females were significantly influenced by the presence of a brother in the sibling generation. There was no relationship between family constellation and sex-role orientation. Feminine women were significantly more congruent with other females in their family than androgynous women. There was a linear trend for androgynous women to be increasingly individuated across the generations.Received her Ph.D. from Yale University. Research interests include observation of children and families in natural settings, longitudinal research with at-risk infants, and rural consultation.Received her Ph.D. from the University of Minnesota. Research interests include development of social competence in family, school, and community environment.Received his Ph.D. from Yale University. Research interests include the socialization of values, professional development, and studies of the family in religious and ethnic community contexts.     

Correlations on radioimmunoassay, fluorescence polarization immunoassay, and enzyme immunoassay of cannabis metabolites with gas chromatography/mass spectrometry analysis of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine specimens.

Results obtained from three commercial immunoassay kits, Abuscreen, TDx, and EMIT, commonly used for the initial test of urine cannabinoids (and metabolites) were correlated with the 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (9-THC-COOH) concentration as determined by GC/MS. Correlation coefficients obtained based on 26 (out of 1359 total sample population) highly relevant samples, are 0.601 and 0.438 for Abuscreen and TDx. Correlation coefficients obtained from a parallel study on a different set of 47 (out of 5070 total sample population) highly relevant specimens are 0.658 and 0.575 for Abuscreen and Emit. The immunoassay concentration levels, that correspond to the commonly used 15 ng/ml GC/MS cutoff value for 9-THC-COOH, as calculated from the regression equations are 82 ng/ml and 75 ng/ml for TDx and EMIT and 120 ng/ml and 72 ng/ml for Abuscreen manufactured at two different time periods. The difference of these calculated corresponding concentrations provides quantitative evidence of the reagent specificity differences.