排序方式: 共有54条查询结果,搜索用时 15 毫秒
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Zheng Zhang M.D. Meghan C. Burke Ph.D. William E. Wallace Ph.D. Yuxue Liang Ph.D. Sergey L. Sheetlin Ph.D. Yuri A. Mirokhin Ph.D. Dmitrii V. Tchekhovskoi Ph.D. Stephen E. Stein Ph.D. 《Journal of forensic sciences》2020,65(2):406-420
Recent reports have demonstrated that genetically variant peptides derived from human hair shaft proteins can be used to differentiate individuals of different biogeographic origins. We report a method involving direct extraction of hair shaft proteins more sensitive than previously published methods regarding GVP detection. It involves one step for protein extraction and was found to provide reproducible results. A detailed proteomic analysis of this data is presented that led to the following four results: (i) A peptide spectral library was created and made available for download. It contains all identified peptides from this work, including GVPs that, when appropriately expanded with diverse hair-derived peptides, can provide a routine, reliable, and sensitive means of analyzing hair digests; (ii) an analysis of artifact peptides arising from side reactions is also made using a new method for finding unexpected modifications; (iii) detailed analysis of the gel-based method employed clearly shows the high degree of cross-linking or protein association involved in hair digestion, with major GVPs eluting over a wide range of high molecular weights while others apparently arise from distinct non-cross-linked proteins; and (v) finally, we show that some of the specific GVP identifications depend on the sample preparation method. 相似文献
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Lawsuits against automakers, oil refineries, and power companies to recover damages allegedly attributable to greenhouse gas emissions are being filed across the country, and can present a real and expensive problem to businesses within these industries. This July, Steadfast Insurance Company sued its policyholder, AES, seeking a declaration that there was no coverage under its commercial general liability policy for a global warming lawsuit in which AES was a named defendant. Using the Steadfast litigation as a rubric, this article reviews the current state of climate change litigation, and evaluates some of the issues that may arise when seeking coverage for this litigation. 相似文献
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This article identifies the characteristics of police officers (officers' background attributes, arrest activity, and assignment) who most frequently receive complaints from citizens regarding the use of excessive force. The data for the study were obtained from a large mid-western municipal police department. The results show that arrest activity, officer age, and officer gender are most strongly related to the receipt of citizen's complaints about excessive force and differentiate high-complaint officers from low-complaint officers. Implications of the findings are discussed. 相似文献
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Meghan G. McDowell 《Contemporary Justice Review》2013,16(4):394-411
Environmental justice advocates have made visible the practice of disproportionately siting hazardous waste facilities in low-income communities of color throughout the USA. Typically, state-corporate actors decide where to place these environmentally undesirable projects, with an eye toward the bottom line rather than the health and safety of particular community members. Through an analysis of secondary data and archival materials, ranging from public hearings to court documents and newspaper accounts, a case study of state-corporate environmental crime and how one rural, historically African American town in Arizona organized to resist the siting of a fourth landfill in their community is explored. Theoretical concepts advanced by Ruth Wilson Gilmore, such as ‘forgotten places’, are put into conversation with the literature on state-corporate crime. An examination of the relationship between environmental inequality, state-corporate crime, and people’s capacity for resistance is presented. 相似文献
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Collaborative and supportive partnerships among academicians and community agency members represent one method of working
successfully toward ending violence against women. Members of academia and service agencies are uniquely poised to collaborate
with one another to foster both domestic violence and sexual assault research agendas as well as direct service to survivors.
This paper provides suggestions and methods of how to create positive, collaborative relationships between academicians and
service providers in the field of domestic violence (DV) and sexual assault (SA). Specifically, we will discuss the reasons
for collaboration, useful steps in developing a partnership, issues of trust and time investment, research methods, and giving
back. 相似文献
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Mitchell Meghan M. Fahmy Chantal Clark Kendra J. Pyrooz David C. 《Journal of Quantitative Criminology》2022,38(3):755-790
Journal of Quantitative Criminology - Longitudinal data offer many advantages to criminological research yet suffer from attrition, namely in the form of sample selection bias. Attrition may... 相似文献
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Meghan E. Rubado 《Public administration》2023,101(2):640-654
In the US system of decentralized federalism, competitive dynamics among local governments are not incompatible with successful interlocal collaboration. Municipalities often collaborate with competing jurisdictions in the same region to provide services and solve problems. Yet, competitive relations among municipalities are expected to complicate collaboration, escalating transaction costs due to divergent goals and lack of trust. This article uses the Institutional Collective Action framework to examine the conditions under which local governments are best able to surmount competition-related hurdles and successfully partner with their chief municipal competitors. An original survey of mayors and councilors is used to test potential predictors of collaboration among top competitors. Results show that municipalities often collaborate with their chief competitors but are less likely to do so when they are situated in municipally-fragmented regions, when they are located in a different county from their top competitors, and when they are fiscally strong. 相似文献