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Bromethalin is a neurotoxin found in some rodenticides. A delusional 21-year-old male presented to a hospital with altered mental status the day after ingesting a bromethalin-based rodenticide. He died 7 days after his self-reported exposure to c. 17 mg bromethalin (equivalent to 0.33 mg bromethalin/kg). His clinicopathologic course was characterized by altered mental status, obtundation, increased cerebrospinal fluid pressure, cerebral edema, death, and diffuse histologic vacuolization of the white matter in the central nervous system seen on microscopic examination at autopsy. The presence of a demethylated form of bromethalin in the patient's liver and brain was confirmed by gas chromatography with mass spectrometry. Clinical signs and lesions observed in this patient are similar to those seen in animals poisoned with bromethalin. This case illustrates the potential for bromethalin ingestion to result in fatal human poisoning.  相似文献   
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  • The past ten years have been marked by significant changes in technology, politics and economics. These changes have affected the social and regulatory environments in which public affairs (PA) officers operate. This paper describes how PA officers at 74 large US corporations perceive these environmental changes and how PA activities have changed from ten years ago.
  • The data reported in this paper were collected first in 1993, then again in 2003. The results show a rather even split between respondents: half (39) believe that their political/regulatory environment is simpler today than was the case ten years ago, half (33) believe that it has become more complicated; half (35) believe there is less social interest in their operations and half (32) believe there is more. The paper then examines the changes in PA activities and performance over the past ten years
  • Overall, PA officers are more pleased with their performance (at least in managing social issues and achieving social objectives) than they were in 1993.
Copyright © 2005 John Wiley & Sons, Ltd.  相似文献   
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Johnson  Bonnie J. 《Publius》2005,35(2):337-355
When discussing the biases of the U.S. Electoral College, researchersconclude that competitive states seem to occur randomly withoutany explanation. This study examines the consistency with whichthe same states have been competitive in presidential electionsfrom 1824 to 2000. It also identifies "spectator" states. Spectatorstates are those that have not been competitive for ten presidentialelections in a row. A statistical analysis illustrates thatthe identities of competitive states have become more unpredictable.In addition, few states have been spectators for long periods.In terms of representation, the facts that competitive statesare not consistent and that there are few spectators mean differentstates are in the presidential spotlight at different times.As opposed to any biases associated with the Electoral College,the changes in consistency coincide with the rise of candidate-centeredpolitics and decreasing voter loyalty to parties. The highlychangeable nature of competitive states strengthens the federalismargument for continuation of the Electoral College.  相似文献   
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Homicide-suicide forms a distinct form of homicide. An analysis of cases in the Yorkshire and Humberside region of England between 1991 and 2005 revealed 37 episodes with 42 victims. Previous studies have shown a high rate of use of firearms. Over the last 2 decades firearms legislation has become more restrictive. In this study all assailants were male, mean age 46.8 years. The commonest method of homicide was strangulation (36%) with 16% killed by firearms. This is a reduction compared with a previous study in the same region. All killers who shot their victims killed themselves with firearms. There were no multiple killings with firearms in this study and no stranger killings. Hanging was the commonest method of suicide. During the same period the use of firearms as a method of homicide increased in England and Wales with handguns, the most common weapon. Nationally, suicide after homicide has remained at a similar rate over the half century and is an uncommon phenomenon. Firearms use remains low in both homicide and homicide-suicide episodes in England, and further analysis is required to determine changes in patterns of killing.  相似文献   
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This research investigates low religiosity as a predictor of violent victimization. The theoretical framework the authors present here posits that religiosity should help structure daily activities in such a way as to (a) limit exposure to offenders by encouraging contact with peers who are less deviant, (b) lessen one's target suitability by inhibiting grievance-causing delinquent activity, and (c) enhance guardianship by fostering stronger bonds with parents and school. Thus, although researchers expect religion to be a bivariate predictor of violent victimization, its influence should be indirect. The authors investigate these claims using two waves from the public-use version of the National Longitudinal Study of Adolescent Health (Add Health). The results indicate that religiosity is a correlate of violent victimization. Consistent with these theoretical claims, the effect of religiosity is not direct, but instead occurs indirectly primarily through its influence on self-reported delinquency and peer deviance.  相似文献   
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