Comparative Toxicology of Intentional and Accidental Heroin Overdose*

Abstract: The demographic and toxicological characteristics of deliberate (SUI, n = 50) and accidental (ACC, n = 927) fatal heroin overdose cases were examined. SUI cases were more likely to be female, had lower body mass indices, were more likely to be enrolled in treatment and less likely to have hepatic pathology. The median blood morphine concentration of SUI cases was significantly higher than that of ACC cases (0.70 vs. 0.40 mg/L, p < 0.001). Blood morphine concentrations of >1 mg/L were seen among 38.0% of SUI cases compared to 13.9% of ACC cases. Being a member of the SUI group remained a significant independent predictor of higher morphine concentrations after controlling for the effects of potential confounders (p < 0.001), other significant predictors being the absence of alcohol (p < 0.001), the presence of methadone (p < 0.05), and the presence of cocaine (p < 0.05). The current data are consistent with the view that suicide forms a small, but distinct, category of heroin overdose cases, rather than overdose being a parasuicidal phenomenon per se.     

Exposure to Interparental Violence and Childhood Physical and Emotional Abuse as Related to Physical Aggression in Undergraduate Dating Relationships

The present study examined whether witnessing interparental violence and experiencing childhood physical or emotional abuse were associated with college students’ perpetration of physical aggression and self-reports of victimization by their dating partners. Participants (183 males, 475 females) completed the Adult-Recall Version of the Revised Conflict Tactics Scale (CTS2-CA; Straus 2000), the Exposure to Abusive and Supportive Environments Parenting Inventory (EASE-PI; Nicholas and Bieber 1997), and the Revised Conflict Tactics Scale (CTS2; Straus et al. 1996). Results of zero-inflated Poisson (ZIP) regressions demonstrated that being female and having experienced higher levels of childhood physical abuse were associated with having perpetrated physical aggression at least once. Among women, exposure to mother-to-father violence and childhood physical abuse were related to the extent of dating aggression. Among men, witnessing father-to-mother violence and childhood emotional abuse were associated with the extent of dating aggression. Witnessing interparental violence and experiencing childhood physical abuse increased the likelihood that women would report victimization, whereas childhood emotional abuse decreased the likelihood that respondents reported dating victimization. Viewing father-to-mother violence and experiencing childhood emotional abuse increased the extent that men reported being victimized by their dating partners, whereas witnessing mother-to-father violence and experiencing physical abuse decreased the extent that men reported being victimized by their dating partners. Results suggest the importance of parent and respondent gender on dating aggression.     

Bankruptcy: Past Puzzles, Recent Reforms, and the Mortgage Crisis

This paper discusses four bankruptcy-related policy issues.First, what is the economic rationale for having a bankruptcyprocedure at all and what defines an economically efficientbankruptcy procedure? Second, why did the number of U.S. bankruptcyfilings increase so dramatically between 1980 and 2005? Third,a major bankruptcy reform went into effect in the United Statesin 2005—what did it do and how did it affect credit andmortgage markets? Finally, the paper discusses the mortgagecrisis, the high social cost of foreclosures, and the difficultyof avoiding foreclosure by voluntarily renegotiation of mortgagecontracts, even when such renegotiations are in the joint interestof debtors and creditors. I also discuss the pros and cons ofgovernment programs to refinance mortgages and the argumentfor giving bankruptcy judges new power to change the terms ofresidential mortgage contracts in bankruptcy.     

Adaptation and evaluation of the PrepFiler™ DNA extraction technology in an automated forensic DNA analysis process with emphasis on DNA yield, inhibitor removal and contamination security

Within the initial step of the forensic DNA analysis process, the DNA extraction efficiency and especially the removal of potential PCR inhibitors is crucial for subsequent steps, e.g. quantification by real-time PCR and amplification of short tandem repeats (STRs). The protocol of the PrepFiler™ Forensic DNA Extraction Kit was optimized for the application on a Tecan liquid handling workstation Freedom EVO^® 150. This modified application of the PrepFiler™ technology was compared with respect to DNA yield, sensitivity and the ability to remove potential PCR inhibitors to an established routine method working on the same liquid handling workstation based on ChargeSwitch^® Technology (CST) from Invitrogen.     

Using Administrative Data to Monitor Racial/Ethnic Disparities and Disproportionality Within Child Welfare Agencies: Process and Preliminary Outcomes

Child welfare administrative data are increasingly used to identify racial/ethnic disproportionality and disparities at various levels of aggregation. However, child welfare agencies typically face challenges in harnessing administrative data to examine racial/ethnic disproportionality and disparities at meaningful levels of analysis due to limited resources and/or tools for reporting. This article describes the process through which a multi-state workgroup designed and developed management reports to monitor racial/ethnic disparities and disproportionality using a web-based child welfare administrative data reporting system. The article provides an overview of the process, outcome, and challenges of the group’s work with the goal of offering a starting point for discussion to others who may be seeking to monitor racial/ethnic disparities and disproportionality, regardless of their reporting system.     

The Role of Postmortem Computed Tomography in the Evaluation of Strangulation Deaths

We explored the value of postmortem computed tomography (PMCT) to augment autopsy in evaluating strangulation fatalities. A literature search identified 16 studies describing autopsy findings in 576 deaths and two studies describing autopsy and PMCT findings in six deaths. Similar cases were identified from our institution, yielding 130 deaths with autopsy findings and 14 deaths with both autopsy and PMCT findings. The presence of laryngohyoid fracture and soft tissue hemorrhage was compared from autopsy and autopsy+PMCT cases. The detection rates of fractures in autopsy and autopsy+PMCT cases were not significantly different. PMCT identified all fractures observed at autopsy and five fractures not identified. While PMCT may not detect soft tissue injuries in decomposed remains or subtle internal hemorrhages in neck injury, it is equally able to detect bony injuries as autopsy and might surpass autopsy in detecting subtle fractures. We conclude PMCT is useful to supplement autopsy in strangulation cases.     

Who’s Your Daddy?

This paper provides a brief explanation and illustration of the phenomenon of semiotics. It then describes the conceptual tools of semiotics and how lawyers can use semiotics in law to create compelling arguments. Last, the paper applies the tools of semiotics to the Pennsylvania Supreme Court case Ferguson v. McKiernan, 940 A.2d 1236 (Pa. 2008), to reveal the shift in social context that made the lines of legal reasoning behind the outcome appear “self-evident.”     

Does Urban Public Housing Diminish the Social Capital and Labor Force Activity of Its Tenants?

This paper investigates the effect of urban public housing on the social capital and labor force activity of its tenants using cross‐sectional survey data from the Multi‐City Study of Urban Inequality (MSCUI). A structural equation model of the hypothesized direct and indirect effects of public housing and neighborhood disadvantage on social capital and labor force activity is specified and fitted to these data. The modeling results suggest that urban public housing is strongly associated with neighborhood disadvantage but has little or no direct effect on either social capital or labor force activity. And while public housing may have indirect effects on social capital and labor force activity through neighborhood poverty, these indirect effects appear to be small. These findings have implications for the current emphasis in urban public housing policy on moving residents into the private housing market and reducing poverty concentration. © 2001 by the Association for Public Policy Analysis and Management.