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This study presents evidence on the cross-cultural generalizability of differential association/social learning theory by testing whether the causal processes of learning attitudes toward deviance, posited by the theory, are equally applicable, and the causal links, specified by the theory, are equally strong in two diverse cultures—the USA and Japan. Drawing on the literature concerning cultural variability in individualism-collectivism, we predicted that the effects of peer reactions to deviance and peer deviance on a person’s attitudes toward deviance should be stronger in Japan than in the USA, and that the mediating effect of a person’s attitudes on the relationship of peer reactions and peer deviance to a person’s deviance should be weaker among Japanese than among Americans. Analyses of comparable survey data from college students in the USA (N?=?625) and Japan (N?=?591) provide generally supportive, but somewhat mixed, evidence regarding our predictions. In both countries, peer reactions to deviance predicted student attitudes toward deviance more strongly than did peer deviance. Peer deviance strongly predicted student deviance, while peer reactions to deviance predicted less strongly, and the effects were mediated by student attitudes in both countries. Contrary to the hypotheses, peer reactions and peer deviance did not predict student attitudes more strongly in Japan than in the USA. Also, peer deviance predicted student deviance more strongly in the USA than in Japan. In agreement with the expectations, the relation between student attitudes and student deviance was stronger in the USA than in Japan.

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Therapeutic antibodies targeting the programmed cell death protein 1 (PD‐1) pathway function as immune checkpoint inhibitors, allowing the immune system to recognize tumors which otherwise escape immune surveillance. However, these agents can also elicit an autoimmune response by inhibiting the ability of non‐neoplastic tissues and regulatory cells to suppress the immune system. Here we present a fatal case of active myocarditis in a 55‐year‐old man with non‐small‐cell lung cancer which occurred following monotherapy with the PD‐1 inhibitor nivolumab (Opdivo). He presented with acute right‐sided heart failure and died 1 day after admission. Postmortem examination revealed multiple gelatinous lesions in the myocardium of the interventricular septum and the bilateral atria and ventricles which had microscopic features diagnostic of myocarditis. Subsequent studies failed to identify an infectious cause. Immune checkpoint inhibitors are an increasingly common addition to anticancer regimens and they should be considered in the evaluation of acute myocarditis.  相似文献   
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This study sought to examine the psychometric properties of the Grooming subscale of the Computer Assisted Maltreatment Inventory (CAMI) in a sample of adult survivors of child sexual abuse. There are currently no other research measures that examine grooming events as experienced by survivors, which underscores the importance of a reliable and valid way of gathering this information. Participants (n?=?295) were adult survivors of child sexual abuse who completed this anonymous study online. The sample was collected through the use of adult survivor of child sexual abuse websites, trauma blogs, and survivor group pages on Facebook. Exploratory Factor Analysis, Confirmatory Factor Analysis, and Cronbach’s Alpha were used to ascertain the reliability and validity of this subscale. These analyses suggest that the Grooming subscale of the CAMI is a reliable and valid measure. This measure is an important addition to the body of research instruments that measure adult survivor of child sexual abuse experiences, particularly since this is the only instrument that examines grooming from this perspective.  相似文献   
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