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101.
Drug use histories were collected from 100 subjects recruited from the "dance scene" in and around Glasgow, Scotland. In addition, each subject donated a hair sample which was analyzed by gas chromatography/mass spectrometry (GC/MS) for amphetamine (AP), methamphetamine (MA), 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MD MA) and 3,4-methylenedioxyethylamphetamine (MDEA). The hair samples were analyzed in two 6 cm segments or in full, ranging from 1.5 to 12 cm depending on the length of the hair. Approximately 10 mg of hair was ground to a fine powder before treatment with beta-glucuronidase/aryl sulfatase. A solid-phase extraction procedure was carried out followed by derivatization with pentafluoropropionic anhydride (PFPA). All extracts were analyzed by gas chromatography/mass spectrometry (GC/MS). Of the 139 segments analyzed, 77 (52.5%) were positive for at least one of the five amphetamines. The drug concentrations found in the hair were compared with the self-reported drug histories. A concordance of greater than 50% was found between the self-report data and levels detected in hair. However, no correlation was found between the reported number of "ecstasy" tablets consumed and the drug levels detected in hair. An increase in the average drug levels measured was observed from low to high use (number of "ecstasy" tablets/month). A large number of false negatives and a low number of false positives were observed.  相似文献   
102.
The concepts of 'lesson drawing' and 'policy transfer' have become increasingly influential ways of understanding public policy, especially in the UK. However, the main proponents of the concepts, Rose for 'lesson drawing' and Dolowitz and Marsh for 'policy transfer', have difficulty in providing convincing answers to three questions that are important for them and those engaged in similar studies. First, can they be defined as distinctive forms of policy- making separate from other, more conventional, forms? 'Lesson drawing' is very similar to conventional accounts of 'rational' policy-making and 'policy transfer' is very difficult to define distinctly from many other forms of policy-making. Second, why does 'lesson drawing' and 'policy transfer' occur rather than some other form of policy-making? The proponents of 'policy transfer' put a set of diverse and conflicting theories under a common framework, obscuring differences between them. Third, what are the effects of 'lesson drawing' and 'policy transfer' on policy-making and how do they compare to other processes? Whilst the effect of more 'lesson drawing' seems to be more 'rational' policy-making, the effect of 'policy transfer' on policy 'success' and 'failure' is less clear. Dolowitz and Marsh redescribe aspects of 'failure' as different forms of 'transfer' rather than giving independent reasons for outcomes based on features of transfer processes. Overall, particularly in the case of 'policy transfer', researchers may be better off selecting from a range of alternative approaches than limiting themselves to these conceptual frameworks.  相似文献   
103.
While several studies have documented how evidence‐based policy instruments affect public policy, less research has focused on what causes changes over time in the analyses mandated by the instruments, especially in Britain. Thus, we take the analytical content of a pivotal regulatory reform instrument (impact assessment) as a dependent variable, draw on learning as a conceptual framework, and explain the dynamics of learning processes across departments, policy sectors, and time. Empirically, our study draws on a sample of 517 impact assessments produced in Britain (2005–2011). Experience and capacity in different departments matter in learning processes. Guidelines also matter, but moderately so. Departments specialize in their core policy sectors when performing regulatory analysis, but some have greater analytical capacity overall. Peripheral departments invest more in impact assessment than core executive departments. The presence of a regulatory oversight body enhances the learning process. Elections have different effects, depending on the context in which they are contested. These findings contribute to the literature on regulation, policy learning, and policy instruments.  相似文献   
104.
This article develops and tests a parliamentarian‐centred decision model of the collaboration between interest groups (IGs) and parliamentarians. We posit that parliamentarians face a trade‐off when deciding on IG ties that offer them either political (policy support and votes) or financial benefits (additional income). We theorise the balance in this trade‐off to be moderated by ideology and tenure because both introduce variations in IG ties’ utility across politicians. Using Swiss longitudinal data from 1985 to 2015 on 743 parliamentarians and their 5,431 IG board positions, we show that parliamentarians become more financial benefit‐seeking over time. This holds in particular if they belong to right‐leaning parties. We also find self‐imposed restrictions for new and left‐leaning parliamentarians on seeking financial benefits. This highlights that parliamentarians are responsive to their partisan constituents when building their IG tie portfolio.  相似文献   
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106.
Collaborations between nonprofit and public sector organizations have become an increasingly important phenomenon in state and local public service delivery since the publication of the Winter Commission report in 1993 . This article focuses on one of the less studied types of public–nonprofit collaborations, those in which philanthropic support from nonprofit organizations supplements the resources and activities of public agencies. Drawing on the case of “nonprofit‐as‐supplement collaborations” that support park services in New York City, this article documents the benefits and drawbacks associated with such collaborations. While they can provide increased resources and encourage management innovations, they also can lead to inequities in the availability and quality of services, the preponderance of particularistic goals over the broader public interest, and the politicization of previously bureaucratic decision making. The authors offer two strategies for public managers to realize more effectively the benefits yet mitigate the shortcomings of these collaborations.  相似文献   
107.
A method for the determination of morphine is post-mortem blood by HPLC with electrochemical detection is described. Blood morphine levels in post-mortem cases are reported and the importance of these in causing death is discussed. These post-mortem levels are compared further with morphine levels in the blood of patients receiving morphine as an analgesic.  相似文献   
108.
Remedial technologies consume energy, produce atmospheric, solid- and liquid-based waste streams and do not always destroy or remove contaminants from the environment. The following discussion reviews those factors associated with the environmental impacts of conducting land quality remediation works with particular focus upon the carbon calculating of different remediation technologies. This work seeks to challenge the conventional paradigm of paying hearsay to the term “sustainability” and challenges the selection of remediation technologies at specific sites in favor of sustainability versus time for non time critical problem holders. By promoting often simple changes to the ways in which we deliver remediation, then added value to society may be delivered while also driving changes in the behavior of market sector thinking.  相似文献   
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110.
Recent debates about the problem-solving capacity of supranational governance within the EU form the background of this paper, which explores the causal conditions for correct and timely transposition of EU directives. In this context, some scholars have pointed to the degree of fit or misfit between European demands and existing national structures and traditions as one of the major factors determining implementation performance. On the basis of empirical evidence from the transposition of six labor-law directives in four member states, the paper demonstrates the limited explanatory power of this approach. Instead, it stresses the importance of domestic party politics and discusses the implications of this finding for the governance capacity of the EU.  相似文献   
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