Sudden unexpected death following exercise and congenital anomalies of coronary arteries. A report of two cases

Two cases of anomalous origin of the left coronary artery from the pulmonary trunk with unusually prolonged post-childhood survival are presented. In both cases, death was associated with physical exertion. The pathological findings included enlarged right coronary ostium, myocardial hypertrophy, endocardial fibrosis, and focal myocardial scarring.     

Freedom,Choice and Public Well-Being: Some Psychological Perspectives

Optimization of well being with minimal regulations seems like a reasonable goal. The problems (and recent progress) in measuring well being are described. The complex meanings of freedom are discussed, with a contrast between “actual” and perceived freedom. Then, the limitations of humans as decision makers in the current complex world in which decisions may have global impact, are described. For the domain of regulations related to food and public health, it is noted that our current scientific knowledge is limited, and policy is influenced by political as well as scientific factors. The risks of misguided regulations are substantial. Finally, the determinants of decisions are described, with particular emphasis on moralization: the historical conversion of a preference into a moral value, as with cigarette smoking in the United States. The consequences and causes of moralization are considered.     

Predicting Phenotype from Genotype: Normal Pigmentation*

Abstract: Genetic information in forensic studies is largely limited to CODIS data and the ability to match samples and assign them to an individual. However, there are circumstances, in which a given DNA sample does not match anyone in the CODIS database, and no other information about the donor is available. In this study, we determined 75 SNPs in 24 genes (previously implicated in human or animal pigmentation studies) for the analysis of single‐ and multi‐locus associations with hair, skin, and eye color in 789 individuals of various ethnic backgrounds. Using multiple linear regression modeling, five SNPs in five genes were found to account for large proportions of pigmentation variation in hair, skin, and eyes in our across‐population analyses. Thus, these models may be of predictive value to determine an individual’s pigmentation type from a forensic sample, independent of ethnic origin.     

Investigation of Different Ways in Which the CODIS 7.0 May be Used in Mass Disaster Identification

DNA analysis is a key method for the identification of human remains in mass disasters. Reference samples from relatives may be used to identify missing persons by kinship analysis. Different methods of applying the CODIS in disaster victim identification (DVI) were investigated. Two searches were evaluated: (i) relating family relatives to a pedigree tree (FPT) and (ii) relating unidentified human remains to a pedigree tree (UPT). A joint pedigree likelihood ratio (JPLR) and rank were calculated for each search. Both searches were similar in average JPLR and rank. In exceptional cases, namely the existence of a mutation different from the CODIS model, a nonbiological father, a mistake in STR, or incorrect profile association, the UPT search returned one true rank, whereas the FPT search returned no results. This paper suggests a novel strategy to overcome these limitations and increase efficiency in conducting identification of mass disaster victims.     

Flying high: A case study of Japanese industrial policy

Japan's policies with respect to industry promotion consist of much more than picking winners and subsidizing them to ensure their success. The highly flexible and adaptive character of Japan's policies is illustrated by the country's efforts to enter the world aerospace industry, an industry in which Japan is handicapped by the absence of a substantial domestic market. To meet the challenge, Japan has concentrated its efforts on altering the very structure of the world market in which it hopes to compete. Japan has participated systematically in international consortia, hoping to use such consortia as a conduit for acquiring access for foreign technology and foreign markets.     

Amoxapine fatalities: three case studies

Amoxapine (Asendin), a recently introduced dibenzoxazepine, has been effective in clinical studies for the treatment of various types of depression. Three amoxapine-related deaths are reported. Quantitation of amoxapine was carried out by gas chromatography using 3% OV-17 column. Blood amoxapine concentrations were 11.5 mg/l, 2.8 mg/l, and 0.89 mg/l. The concentrations are many-fold higher than the reported therapeutic serum concentrations of 0.21 mg/l. These cases illustrate the potential toxicity and lethality of amoxapine overdose and the need for caution in prescribing a large amount of amoxapine to patients with suicidal tendencies.     

Death during transforaminal epidural steroid nerve root block (C7) due to perforation of the left vertebral artery

Treatment for individuals suffering from migraines and pain due to an inflammation or impingement of a nerve range from noninvasive methods such as massage, physical therapy, and medications to invasive methods such as epidural steroid injections and surgery. Each method of treatment has an associated level of risk. While minor to moderate complications from such procedures do occur, deaths are very rare. We report the first cited case of a death associated with the pain management procedure called nerve root block, also referred to as a transforaminal epidural steroid injection. We present the medical history and autopsy findings of a 44-year-old white female who died of massive cerebral edema secondary to the dissection of the left vertebral artery and subsequent thrombosis due to the perforation of that artery by a 25-gauge spinal needle during a C-7 nerve root block.     

Coalition-Targeted Duvergerian Voting: How Expectations Affect Voter Choice under Proportional Representation

Inspired by analyses of majoritarian systems, students of consensual polities have analyzed strategic voting due to barriers to party success, namely, district magnitude and threshold. Given the prevalence of coalition governments in proportional systems, we analyze a type of strategic voting seldom studied: how expected coalition composition affects voter choice. We identify Duvergerian behavior by voters targeted at the coalition formation stage. We contend that when voters perceive their preferred party as unlikely to participate in the coalition, they often desert it and instead support the lesser of evils among those they perceive as viable coalition partners. We demonstrate our argument using data on coalition expectations from the 2006 Israeli elections. We find an appreciable albeit differential effect of coalition expectations on voter choice. Importantly, results hold controlling for ideological and coalition preferences. Lastly, we explore a broad cross-national comparison, showing that there is less, not more, proximity voting where coalitions are prevalent.     

Honor and Dignity in the Film Unforgiven: Implications for Sociolegal Theory

This article calls attention to "honor" and "dignity" as two fundamental, antithetical bases of unique value systems, both highly significant to social orders and legal systems in the contemporary Western world. The article argues that in this comparative context, the relatively new dignity-based value system may be better defined and articulated; at the same time, the overlooked, traditional honor-based value system, which underlies much of contemporary reality, can be better identified and replaced or at least modified by a dignity-based one. Rather than look to specific sociolegal realities, the article presents this line of thought from a "law-and-film" perspective, i.e., through the close reading of a single feature film: Clint Eastwood's Unforgiven . This contemporary, widely familiar, and immensely popular Western exposes the ugly face of the honor-based value system at the heart of the Western film genre; further, it subversively undermines this value system, replacing it with a dignity-based one. In so doing, the film expresses deep faith in the human capacity to transform, calling on real-world social and legal systems to follow in its footsteps and apply the same critical analysis and reformative activism to Western law and society at large.     

Interethnic contacts in an alternative educational environment: The Israeli Shelef project

The purpose of the study was to examine the unique interethnic contact situation provided by the Israeli Shelef project and its consequences in changes of ethnic stereotypes among Shelef participants. The study population consisted of all 49 Shelef members during the academic year 1979–1980, who resided in seven different development towns. They responded to an anonymous questionnaire which solicited information concerning their personal background and measures of interethnic relations. The data indicate that the tendency to generalize and to relate to people categorically decreased over the year and was replaced by a more individualistic approach to people different than one's own. Also, Shelef members' valuation of eastern Jews and development townspeople became higher, and their readiness to associate with them became complete and unconditional at all levels of intimacy. The implications of the project for providing adolescents with meaningful experiences, bringing the school and the real world closer together, are also discussed.Received Ph.D. in sociology from the Graduate Center of the City University of New York. Main interests are sociology of education, political socialization, and sociology of the family.Received M.A. in the sociology of education from Tei-Aviv University. Currently working in teachers' training in the social sciences.