Restriction fragment length polymorphism analysis of forensic science casework in the People's Republic of China.

Restriction fragment length polymorphism (RFLP) analysis for the purpose of individualization is now being used in casework in the People's Republic of China. This report describes the use of the multilocus minisatellite probe 33.15 to solve three cases, including two homicides and a rape. In the third case, fetal tissue was analyzed to prove that the alleged rapist was, in fact, the father. In each case, analysis of deoxyribonucleic acid (DNA) resulted in a positive match. The probability of chance association of the DNA fingerprint was calculated as 5.6 x 10(-12), which is similar to the figures reported in the literature.     

A LOG‐MULTIPLICATIVE ASSOCIATION MODEL FOR ALLOCATING HOMICIDES WITH UNKNOWN VICTIM‐OFFENDER RELATIONSHIPS*

This research note critically evaluates conventional methods for allocating homicides with an unknown victim/offender relationship to meaningful categories, and it proposes an alternative approach. We argue that conventional methods are based on a problematic assumption, namely, that the missing data mechanism is “ignorable.” As an alternative to these methods, we propose an imputation algorithm derived from a log‐multiplicative model that does not require this assumption. We apply this technique to estimate levels of homicides disaggregated by victim/offender relationship using the Federal Bureau of Investigation's Supplementary Homicide Report (SHR) data for 1996 and 1997, and we compare the resulting estimates with those obtained from the application of conventional procedures. Our results yield a larger proportion of stranger homicides than are obtained from the conventional methods.     

大鼠液压冲击脑损伤TGF-β1及其受体TβR I的表达

目的观察脑损伤后TGF-β1及其受体TβRI蛋白表达及其时序性变化,探讨脑损伤的分子机制及法医学脑损伤时间推断。方法用免疫组织化学方法观察大鼠液压冲击脑损伤后TGF-β1及其受体TβRI蛋白在伤后不同时间(30 min、1 h、3 h、6 h、12 h、1 d、3 d、7 d)的表达情况,以正常大鼠及手术大鼠作为对照。结果 (1)正常及手术对照组大鼠脑组织内有低水平的TGF-β1及TβRI表达;(2)脑损伤后1～3d,大脑皮质和脑干TGF-β1/TβRI蛋白表达逐渐增加,7 d时仍维持在高表达水平;(3)海马冲击后12 h～1 d逐渐增加,3 d时仍处于高表达水平,7 d时已开始下降。结论脑损伤可诱导TGF-β1/TβRI基因在脑内表达,其时序性改变可望用于法医学脑损伤时间推断。     

The individuality of fibres used to provide forensic evidence--not all blue polyesters are the same.

Fibres used in forensic casework suffer from a disadvantage common to other forms of trace evidence--it is not possible to state with absolute certainty that they originate from a specific source. Target fibre studies, population studies and research on 'blocks of colour' have effectively demonstrated the polymorphism of textile fibres (particularly man-made ones) and have shown that when a fibre is believed to have a specific putative source, the chance that it has originated from a different source purely by coincidence is extremely remote. A study by Houck MM (Houck MM, Inter-comparison of unrelated fibre evidence. Forensic Science International 2003; 135: 146-149) has shown that no coincidental matching fibres were recovered from items of clothing examined in 20 unrelated crimes. The study involved over two million comparisons. This work goes a step further, and using the example of blue polyester fibres shows that even within a very narrow segment of the whole general fibre population, many examples of a specific colour/type of man-made fibre taken from random sources can be compared and the chance of any two being the same is very low. These studies should help to show the specificity and value of transferred fibres in providing forensic evidence.     

Doctors in Extremity

Book Reviews in This Article:
Robert Jay Lifton, The Nazi Doctors: Medical Killing and the Psychology of Genocide.
Eric Stovcr and Elena O. Nightingak, eds., The Breaking of Bodies and Minds: Torture, Psychiatric Abuse and the Health Professions.
Elliot S. Valenstein, Great and Desperate Cures: The Rise and Decline of Psychosurgery and Other Related Treatments for Mental Illness.