The entrepreneurial puzzle: explaining the gender gap

We document the substantial gender gap that exists among university scientists with regard to entrepreneurial activity using a variety of measures and explore factors leading to the disparity. We focus particularly on the biomedical sciences. The contextual explanation that women are under-represented in the types of positions from which faculty typically launch entrepreneurial activity is the most obvious. But the data suggest that for the biomedical sciences context is not sufficient in explaining the entrepreneurial gap. We look elsewhere to factors affecting supply and factors affecting demand. The former include gender differences in attitudes towards risk, competition, “selling” of “science,” type of research and geographic location. The latter include the role of networks, preferences of venture capitalists and “gender discounting.” We explore the associated hypotheses. We provide few tests and conclude that the research agenda is wide open and interesting.

Fatal intoxication with tianeptine (Stablon)

Tianeptine (Stablon), although structurally similar to tricyclic antidepressants, acts by enhancing the reuptake of serotonin. A fatal case is presented involving a 26-year-old man, found lying in bed with a "mushroom of foam" around his mouth. Empty blister packs of Stablon and a suicide note were found next to the body. A liquid-liquid extraction procedure with n-hexane: ethyl acetate and n-hexane: 2-propanol, followed by LC-DAD-MS analysis, using positive mode electrospray ionization was performed. The detection limit was 0.001 microg/mL. The toxicological results revealed the following tianeptine concentrations in the post-mortem samples: blood 5.1 microg/mL; urine 2.0 microg/mL; liver 23 microg/g; stomach contents 22 mg. Femoral blood analyses also revealed an ethanol concentration of 0.53 g/L. The present method was also developed and validated for the other post-mortem specimens, since no previous published data had confirmed the post-mortem distribution of tianeptine. The absence of other suitable direct causes of death (macroscopic or histological) and the positive results achieved with the toxicological analysis led the pathologist to rule that death was due to an intoxication caused by the suicidal ingestion of tianeptine in combination with alcohol.