What are the best quorum rules? A laboratory investigation

Public Choice - Many political systems with direct democracy mechanisms have adopted rules preventing decisions from being made by simple majority rule. The device added most commonly to majority...     

Revisiting the choice model of Ponzi and Pyramid schemes: analysis of case law

This exploratory study operationalizes the variables comprising the choice model of white collar crime through analyzing cases decided by federal courts, the Securities and Exchange Commission (SEC), and the Federal Trade Commission (FTC). Cases were extracted from the LEXIS-NEXIS, WESTLAW, and the NERA Economic Consulting databases and categorized according to the indicators of the choice model: size of pool of criminally predisposed, supply of lure, prevailing beliefs about credibility of external oversight, internal oversight and self-restraint, and supply of criminal opportunities. The findings show that unequal access to information among the investors and misuse of trust and affinity relationships affected the size of the pool of criminally tempted individuals. Supply of lure was affected through advances in modern technology and promises of wealth and material success at low costs and risks. Prevailing beliefs about the credibility of external oversight and internal corporate regulatory controls were affected by the efficiency and effectiveness of enforcement authorities. Variables described by the choice model of white collar crime can be operationalized through analysis of existing case law.     

Disaffected democrats: Political attitudes and political action in Portugal

Three decades after the fall of the Portuguese authoritarian regime, support for democracy has become widespread among the mass public. However, similarities between Portugal and other more established democracies should not be overestimated. In most of the latter, several studies have found increasing political and civic activism on the part of pro-democratic and politically sophisticated citizens, who are nevertheless increasingly dissatisfied with democratic performance. However, the most prevalent and consequential attitudinal-behavioural syndrome in Portugal is less one of ‘democratic dissatisfaction’ than one of ‘democratic disaffection’, entailing low levels of political engagement and participation.     

Social Norms and the Paradox of Elections’ Turnout

People vote although their marginal gain from voting is zero.We contribute to the resolution of this paradox by presentinga model for equilibrium configuration of attitudes regardingthe decision to vote. Each individual is seen as an element ofa social network, within which pairs of individuals expressideas and attitudes, exerting mutual influence. We model therole of such networks in propagating the mutual influenceacross pairs of individuals. We show that it may suffice thata small set of individuals have a strong feeling about showingup to vote to generate a significant turnout in elections.     

Influence of multiple injections of human chorionic gonadotropin (hCG) on urine and serum endogenous steroids concentrations

Since it is established that human chorionic gonadotropin (hCG) affects testosterone production and release in the human body, the use of this hormone as a performance enhancing drug has been prohibited by the World Anti-Doping Agency. Nowadays, the only validated biomarker of a hCG doping is its direct quantification in urine. However, this specific parameter is subjected to large inter-individual variability and its determination is directly dependent on the reliability of hCG immunoassays used. In order to counteract these weaknesses, new biomarkers need to be evidenced. To address this issue, a pilot clinical study was performed on 10 volunteers submitted to 3 subsequent hCG injections. Blood and urine samples were collected during two weeks in order to follow the physiological effects on related compounds such as the steroid profile or hormones involved in the hypothalamo-pituitary axis. The hCG pharmacokinetic observed in all subjects was, as expected, prone to important inter-individual variations. Using ROC plots, level of testosterone and testosterone on luteinizing hormone ratio in both blood and urine were found to be the most relevant biomarker of a hCG abuse, regardless of inter-individual variations. In conclusion, this study showed the crucial importance of reliable quantification methods to assess low differences in hormonal patterns. In regard to these results and to anti-doping requirements and constraints, blood together with urine matrix should be included in the anti-doping testing program. Together with a longitudinal follow-up approach it could constitute a new strategy to detect a hCG abuse, applicable to further forms of steroid or other forbidden drug manipulation.     

Assessment of age and sex by means of DXA bone densitometry: application in forensic anthropology

An effective way to reveal the history of drug abuse is to determine the parental drug and its metabolites in hair. Here, a quantitative HPLC-Chip-MS/MS method was developed for simultaneous measurement of ketamine and its metabolite norketamine in human hair. Ketamine and norketamine were extracted from hair by acid hydrolysis, and then enriched by organic solvent extraction. The chromatographic separation was achieved in 15 min, with the drug identification and quantification by a tandem mass spectrometer. The linear regression analysis was calibrated by deuterated internal standards with a R(2) of over 0.996. The limit of detection (LOD) and the limit of quantification (LOQ) for ketamine and norketamine were 0.5 and 1 pg/mg of hair, respectively. The standard curves were linear from the value of LOQ up to 100 pg/mg of hair. The validation parameters including selectivity, accuracy, precision, stability and matrix effect were also determined. In conclusion, this method was able to reveal the present of ketamine and norketamine with less hair from the drug abusers, and which had the sensitivity of ～1000-fold higher than the conventional method. In addition, the amount of ketamine and norketamine being detected in different hair segments would be useful in revealing the historical record of ketamine uptake in the drug abusers.     

Psychological and behavioral adjustment in female youths with high or low psychopathic traits

The aim of the present study was to analyze the role of psychopathic traits in female juvenile delinquency. Using a sample of 236 young females from the Juvenile Detention Centers of the Portuguese Ministry of Justice and schools in the Lisbon area, a group of female youths with high psychopathic traits (n = 118; M = 15.84 years of age; range = 14–18 years of age) and a group of female youths with low psychopathic traits (n = 118; M = 15.77 years of age; range = 14–18 years of age) were formed based on the Portuguese version of the Antisocial Process Screening Device-Self-report (APSD-SR). The results showed that young females with high psychopathic traits start engaging in criminal activities and come into contact with the justice system earlier in life; exhibit higher levels of behavioral problems, conduct disorder, delinquent behaviors and serious criminality; and demonstrate lower levels of self-esteem and pro-social behavior. The importance of some variables in predicting group membership (high versus low psychopathic traits) was established through a binary logistic regression. Our findings reinforce the importance of the psychopathy construct for the early identification of potentially high-risk female youths and for the assessment of female youths who have already come into contact with the judicial system.     

Camouflaging Facial Emphysema: A new syndrome

Some cosmetic products manufactured in Korea for the treatment of eczema, seborrhea and psoriasis have been suspected to contain anti-inflammatory corticosteroids such as prednisolone, hydrocortisone, betamethasone, dexamethasone and triamcinolone acetonide without these ingredients being indicated on the label. Due to their severe side effects such as permenent skin atopy, these corticosteroids have to be monitored in cosmetic products from a forensic point of view. Many cosmetic product samples (N=65) have been collected from both local and online markets in Korea. The corticosteroid content of these samples was analyzed by LC-MS/MS with diagnostic ions (m/z). Linearity was studied with 0.1-10 μg/mL range in all corticosteroids. Good correlation coefficients (r(2)≥0.997) were found and the limits of quantification were 4.68-7.97 ng/mL for each of the corticosteroids. At three different concentrations spanning the linear dynamic ranges, mean recoveries were 97.2-113.5%and precisions (RSD) for intra-day and inter-day analysis were less than 8.9%. Also, accuracy (Bias %) was less than 11.8%. The results showed that between 0.76-0.94 μg/g levels of prednisolone were detected in four cosmetic products and triamcinolone acetonidewas detected with a concentration in the range of 11.5-272 μg/g in nine samples. This fact reveals that some manufacturers have arbitrarily added these corticosteroids in their cosmetic products without indicating them on the label. Thus, these cosmetic products have to be monitored and if proven illegal preparations removed from the market.     

Experimental forensic scenes for the characterization of ground-penetrating radar wave response

Over the last few decades, the use of non-intrusive geophysical techniques, which allows for coverage of an entire crime scene in a reasonable amount of time, in forensic investigation has increased. In this study, we analyze the effectiveness of ground-penetrating radar (GPR) in forensics. Experimental scenes were simulated and some of the most commonly buried items in actual crime scenes were introduced, such as bone remains, guns and drug caches. Later, a GPR survey was conducted on the experimental grids with a 500 MHz antenna. The final purpose was to characterize the radar wave response expected for each set of remains to assist with its identification in later actual investigations. The results collected provided promising information that can be used when surveying real cases. Nevertheless, there were some interpretational difficulties regarding the sizes of the items and the electromagnetic properties of the materials. For these cases, finite-difference time-domain modeling was employed to achieve an advanced interpretation of the field data. The simulated models used were built from accurate geometric data provided by photogrammetric methods, which replicate the experimental scenes in fine detail. Furthermore, this approach allowed for the simulation of more realistic models, and the synthetic data obtained provided valuable information for assisting in the interpretation of field data. As a result of this work, it was concluded that GPR can be an effective tool when searching for a variety of materials during a crime scene investigation.