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191.
目的:探讨益气活血方对气虚血瘀证局灶性脑缺血再灌注损伤大鼠Fas、FasL蛋白表达的影响。方法:采用气虚血瘀证局灶性脑缺血再灌注损伤大鼠模型,用线栓法阻塞大鼠大脑中动脉复制局部脑缺血再灌注模型,缺血2h后再灌注l,3,7d。用免疫组化染色法分别检测缺血皮质Fas、FasL蛋白表达。结果:与模型组比较。益气活血方组Fas、FasL蛋白表达显降低。结论:益气活血方可能通过抑制Fas、FasL蛋白表达,减轻气虚血瘀证局灶性脑缺血再灌注损伤。 相似文献
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Mylon Winn Assistant Professor 《国际公共行政管理杂志》2013,36(5):797-819
Discussions in the representative bureaucracy literature have tacitly assigned the responsibility of representing the interests of blacks to individual black administrators. Relying on black employee groups (or solidarity groups) to represent the interests of blacks is ignored. The possibility that black members of organizations have a group interest to be represented is not considered in the literature. Assigning there presentation responsibility to individual black administrators is rejected be cause of barriers that can be created by racial road blocks (to kenism and different perceptions of race relations). It is argued that solidarity groups are a more effective means of representing the interests of blacks. Assigning the responsibility to solidarity groups should: (1) neutralize the effects of racial road blocks; (2) limit individual representation activities and thus permit each black administrator to concentrate on job performance; and (3) shift the focus in there presentative bureaucracy literature away from the individual and start concentrating on the representation activities of solidarity groups. 相似文献
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Gray E. Robert Assistant Professor 《国际公共行政管理杂志》2013,36(7):1367-1394
Open meetings laws are designed to make the process of governmental decision making more accessible to the general public. The objective of this study is to explore the views of key governmental officials on the operation and effects of Florida's open meetings (sunshine) law. The interviews uncovered considerable dissatisfaction with many of its provisions. Florida's sunshine law is one of the most comprehensive in the country and can provide insight on the potential effects of other state or local sunshine laws. The analysis is based upon the administrative perspective of city managers, city clerks and city attorneys in Dade County, Florida. This convenience sample of Dade County administrators perceives that significant costs are imposed by the operation of the sunshine law. There is a clear consensus that the presence of the media alters the process of policy making, increases the amount and degree of political posturing, increases the time to reach consensus, and inhibits the candor and openness of the deliberations. The respondents report that the open meeting provisions are so burdensome that council and board members routinely violate its provisions in order to discuss sensitive issues in private. 相似文献
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