Norms and the Categories of Inaccurate Thinking

Two ways of thinking can be distinguished. The accurate way, based on causality and explanation, recognizes its ignorance on many items, but tries to organize and foster its knowledge on a solid basis. The innacurate way, based on indeterminacy, chance and free will, assumes with resignation there are segments of reality which cannot be known at all and does not try to go further on those items. Moral and legal discourses run the second way. That assumption tends to prevent them from fostering knowledge and leads normative sciences to irrationality and perplexity.     

One image is worth more than a thousand words: producing an atlas of medical signs for teaching clinical and forensic toxicology

Clinical and forensic toxicology are critically involved in the acquisition of basic skills to correctly suspect intoxication, collect biological and non-biological materials for toxicological analysis, comprehend the complexities inherent to laboratory activity, and understand the fundamentals of toxicokinetics and toxicodynamics that underlie the interpretation of results. This works presents a pedagogical innovation proposal for the teaching of clinical and forensic toxicology based on a compilation of more than 3 000 cases where the image was fulcra for suspicion. The experience in this article follows the model practiced in bachelors, masters, and PhD degrees, as well as in other continuing training courses, where we are teaching toxicology for more than 15 years. All these levels of education are considered fundamental to the sound development of this science. This approach aims also to offer strength to the intervention of the true toxicologist in all the toxicological phases, besides the classic analytical chemistry. Indeed, it is impossible to provide effective clinical and forensic toxicological interpretations without a proper and broad education, and not thinking exclusively in terms of laboratory techniques. In the future, it will be interesting to evaluate knowledge retention and to propose a database of videos of signs related to intoxications.     

Euvoluntariness and just market exchange: moral dilemmas from Locke’s Venditio

It is a maxim of Public Choice that voluntary exchanges should not be interfered with by the state. But what makes a voluntary market exchange truly voluntary? We suggest, contra much of the economics literature, that voluntary exchange requires consent uncoerced by threats of harm, but that this is not sufficient. In particular, a person pressured to exchange by the dire consequences of failing to exchange—e.g., dying of thirst or hunger—is still coerced, and coerced exchange cannot be voluntary. The weaker party’s desperation gives the other party unconscionable bargaining power. We argue for a distinction, based on a neologism: in the case of coercion by circumstance but not by threat, exchange is still voluntary in the conventional sense, but it is not euvoluntary (i.e., truly voluntary). We will argue that all euvoluntary exchanges are just, while non-euvoluntary exchanges may or may not be unjust; that in competitive markets all exchanges are just, even those that are not euvoluntary, while in bilateral monopolies some exchanges are neither euvoluntary nor just. We will propose a mental device, the “fictitious negotiation”, to determine the just price in non-euvoluntary market exchanges. A primitive version of these ideas can be found in a little known monograph by John Locke, which we will analyze in detail.     

The electoral connection in presidential systems: non-legislative actions inside the Chilean congress

The purpose of this article is to explore how the features of districts affect representation activities in the Chilean Congress. Based on an analysis of interventions by deputies in the so-called Incidents Hour (Hora de Incidentes), we argue that district conditions affect the kind of appeals that deputies make. Specifically, we test two main hypotheses: a) that the degree of rurality of districts predicts greater use of policy intervention at the local level (local credit claiming), and b) that distance from the centre is an incentive for deputies to taking a position on local issues (local position taking). This article contributes to an understanding of how institutional spaces in the Congress serve not only as instruments for legislation but also, and with equal relevance, for representing constituents at the district level.     

Assessing the impacts of a peer-to-peer training programme for women in Peru

This article reports on research that aimed to assess the economic and social impacts of a peer-to-peer training programme targeted to women in Peru, looking at overall and differentiated impacts according to design features, on a sample of 300 women in participant and non-participant communities. The study found significant positive impacts on women’s time devoted to work outside the house and in their saving propensity, although no significant change on time allocated to domestic activities. It also detected some effects on an index of family cohesion and on home improvements. Finally, there was evidence that some design features influence the magnitude and significance of these impacts.     

Near Infrared Spectroscopy Detection and Quantification of Herbal Medicines Adulterated with Sibutramine

There is an increasing demand for herbal medicines in weight loss treatment. Some synthetic chemicals, such as sibutramine (SB), have been detected as adulterants in herbal formulations. In this study, two strategies using near infrared (NIR) spectroscopy have been developed to evaluate potential adulteration of herbal medicines with SB: a qualitative screening approach and a quantitative methodology based on multivariate calibration. Samples were composed by products commercialized as herbal medicines, as well as by laboratory adulterated samples. Spectra were obtained in the range of 14,000–4000 per cm. Using PLS‐DA, a correct classification of 100% was achieved for the external validation set. In the quantitative approach, the root mean squares error of prediction (RMSEP), for both PLS and MLR models, was 0.2%w/w. The results prove the potential of NIR spectroscopy and multivariate calibration in quantifying sibutramine in adulterated herbal medicines samples.