The state of the discipline in American political science: be careful what you wish for?

This article is an attempt to survey and analyse current developments in American political science with particular reference to the current wave of institutionalist theory. The main thrust of this article is to argue that the current concerns of the field are hardly new issues, but rather perennial. We argue that the current 'state of the discipline' is in many ways more a function of recurrent intellectual dilemmas of a general social scientific nature than they are about the particulars of the current debates in the field. Most relevant to a British journal, we shall attempt to 'step outside the hermeneutic circle', and suggest which aspects of contemporary American political science are most relevant to British political scientists.     

From Sancitity to Screening: Genetic Disabilities, Risk and Rhetorical Strategies in Wrongful Birth and Wrongful Conception Cases

This analysis scrutinises the rhetorical strategies used by judges in wrongful life and wrongful birth actions as evidence for the assertion that the judicial reading of public policy in such cases has undergone a significant shift which is likely to accelerate as genetic knowledge grows and health care resources shrink. The implications of the predicted move towards increased genetic testing of prospective parents are traversed in relation to feminist analyses of the impact of genetics on reproductive technology. These are viewed as forming a nexus with the current social constructions of disability and the contemporary cultural preoccupation with risk, in a context of the increasing commercial importance of genetic information. It is argued that women cannot make free and informed choices about genetic testing and pregnancy unless legal and social mechanisms which protect those choices are in place. This revised version was published online in August 2006 with corrections to the Cover Date.     

Successful DNA typing of ultrafiltered urines used to detect EPO doping

Endogenous and exogenous erythropoietin (EPO) present in urine can be distinguished according to their isoelectric profiles. This methodology requires urine samples to be concentrated about 200 to 1000 times with manipulations that should remove most of the cells occurring in the original sample. In this study, we tried to obtain DNA profiles from 10 ultrafiltered urines (retentates) in order to evaluate whether a formal genetic identification was technically feasible. No nuclear DNA profiles could be established from retentates, despite 34 PCR-cycles amplifications. Contrastingly, mitochondrial DNA (mtDNA) profiles were obtained for 9 out of the 10 retentates. Apart from some particularities, retentate mtDNA profiles were all distinct and matched mtDNA profiles of corresponding reference samples.     

Pre-nuptial Agreements the end of romance or an invaluable weapon in the wealth protection armoury?

Media attention directed at high profile divorce cases has emphasizedthat trust assets may be included in divorce settlements andthe advantages which pre-nuptial and similar agreements canplay in achieving acceptable and less traumatic settlements.This article examines the role that pre-nuptial agreements andsimilar measures can play in achieving an acceptable settlement.     

Neighborhood Socioeconomic Deprivation in Early Childhood Mediates Racial Disparities in Blood Pressure in a College Student Sample

The influence of childhood contexts on adult blood pressure is an important yet understudied topic. Using a developmental perspective, this study examines the association between neighborhood socioeconomic disadvantage in early childhood (0–5?yrs), middle childhood (6–12?yrs) and adolescence (13–18?yrs) on subsequent blood pressure in young adulthood. Data were from 263 college students (52% Black; M_age?=?19.21 years) and neighborhood socioeconomic disadvantage was measured using a tract-level Area Deprivation Index. Neighborhood disadvantage in early childhood was significantly associated with diastolic blood pressure and explained 22% of the race difference between Black and White adults. The findings are consistent with the notion that early childhood may be a sensitive period for the effects of neighborhood disadvantage on blood pressure.

     

Law and Market Economy: The Triadic Linking of Law,Economics, and Semiotics

International Journal for the Semiotics of Law - Revue internationale de Sémiotique juridique -