Determination of methadone in human hair by radioimmunoassay

The concentrations of methadone in human hair were measured. The washed hair was cut in 1-mm pieces approximately, then incubated overnight at 45 degrees C with 0.1 m HCl. The extracts were alcalized by 1 m NaOH and diluted by phosphate buffer, pH 7.4. The methadone concentrations were determined by radioimmunoassay. The method is simple, rapid, and practicable for routine determination.     

Structural injustice and the legitimacy of the state-centric system

ABSTRACT

Catherine Lu’s seminal Justice and Reconciliation in World Politics is right to stress the enduring nature of some colonialist structural indignities. It is less clear, however, if structural injustices justify Lu’s demand for revolutionary changes of the global order. Before transforming the pluralist state-centric system, we need transparent criteria that help us agree on the severity of structural injustices. Considering Lu’s strong focus on the colonialist origins of contemporary injustices, one would also like to know if and how their historical background affects their present moral status. The essay concludes that, in a multicultural global society with diverse moral values, we should focus on tackling the most glaring injustices and on rectifying those where accountabilities are least controversial.     

Differential effects of general versus cued invitations on children’s reports of a repeated event episode

The ability to describe individual episodes of repeated events (such as ongoing abuse) can enhance children’s testimony and assist the progression of their cases through the legal system. Open-ended prompts have been advocated as a means to assist children in accurately retrieving information about individual episodes. In the current study, two subtypes of open-ended prompts (cued and general invitations) were compared for their effects on five- to nine-year-olds’ (n?=?203) reports about individual episodes of a repeated event. Interviews occurred 1–2 weeks after the last of 4 event sessions. Cued invitations assisted children to provide specific details about individual episodes of a repeated event, while general invitations were useful to elicit more broad happenings of the episodes. The accuracy of responses to general invitations was similar for children of all ages up to one week after the event, but at a longer interview delay younger children were less accurate than older children. There were no differences in the accuracy of responses to cued invitations as a function of age or interview delay. Results suggest that interviewers tasked with eliciting accounts of individual episodes from a repeated event, such as ongoing abuse, should consider the differential efficacy of each prompt-type on children’s reports.     

Specificity of sibship determination using the ABI Identifiler multiplex system

Fifty known siblings and fifty unrelated pairs were genotyped using the ABI Identifiler STR system and sibship indices computed for each pair. Combined sibship indices (CSIs) for the known siblings ranged from less than 10 to greater than 1 billion. CSIs for the unrelated pairs ranged from 4.5 x 10(-8) to 0.12. In the known sibling group the percentage of loci where both alleles matched was approximately 40%, while the percentage of loci where neither matched was approximately 10%. In the non-sibling group, the percentage of loci where both alleles matched was approximately 6%, while the percentage of loci where neither matched was approximately 45%. Interestingly, the percentage of loci where a single allele matched was the same in both the known siblings and unrelated pairs, approximately 50%.     

A possible source of reference DNA from archived treated adhesive lifters

During the course of a double murder trial, it became apparent that the two adhesive lifters from the two cadavers had been mislabeled before being presented in court. The question was raised whether DNA testing from the biological material remaining attached to the lifters could resolve this mix-up. In fatal shooting cases where a bullet has been fired through a body surface, an adhesive lifter is applied directly to the entrance wound. The total nitrite residues, as well as biological material surrounding the wound (blood, hair, tissue) are transferred to the adhesive lifter. The nitrite residues are used for estimating firing distance. In a worst-case scenario, the biological material on the lifter may be the only remaining reference material from a victim. In this paper, we examined whether the biological material retrieved from adhesive lifters could be used for DNA typing after the lifters had been treated for GSR pattern. In as much as the biological material found on the lifters can be typed and profiled following physical and chemical treatment, we submit that archived adhesive lifters can be used as a future source of reference DNA from cadavers where no other sample is available.     

Fatal craniocerebral trauma in a young child. I: Forensic documentation,model generation and geometric impact conditions

The aim of forensic biomechanics is the reconstruction of traumatic events based on the pathological findings in the victim's morphology and on the traces and shapes of the traumatizing tools. The introduction of Streifenlichttopometrie into forensic science enables 3-dimensional and proportionally accurate documentation of the victim's body and injuring agent with submillimeter precision. The advantages of this method of documentation are the possibilities of producing animated models which correspond exactly to the body's shape and injury topography, and of ascertaining the physical parameters (centers of mass, moments of inertia) of the various body parts and the geometrical impact conditions for the reconstruction of the injury dynamics. This way of proceeding thus enables more precise models than hitherto possible for kinetic and dynamic reconstruction. In the case of an infant who was fatally injured by a wooden sculpture the generation and application of computer aided 3-dimensional reconstruction models are shown.