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111.
Bruce Patsner 《The Journal of law, medicine & ethics》2009,37(2):305-317
The recent United States Supreme Court decision in Riegel v. Medtronic, Inc. affirmed the doctrine of pre-emption protection only for those medical devices reaching U.S. markets via the PMA (premarketing approval) process and preserved the previous Lohr v. Medtronic decision's lack of preemption protection for those medical devices marketed via the generally more abbreviated 510(k) clearance mechanism. This paper reviews the logic and faults of the Riegel decision and discusses the implications of the Riegel decision for pre-emption protection for other classes of FDA-approved medical products. 相似文献
112.
Selwyn Stanley 《Journal of family violence》2008,23(8):767-776
This study compared 75 wives of alcoholics with an equal number of wives of non-alcoholics matched on key socio-demographic
variables, using a cross sectional ex-post facto research design. Instruments to assess the extent of conflict and danger
perceived by them in their marital relationship, besides the communication apprehension experienced towards their partners
were administered. Analyses showed that the wives of alcoholics as a group had higher levels of conflict, perceived more danger
and experienced more apprehension in relating with their spouses, than the subjects of the reference group. Results indicate
the need to consciously focus on the spouse of the alcoholic and to help her resolve various marital issues with which she
is faced. Implications for therapeutic intervention with couples in alcohol complicated relationships to enable them overcome
their marital life deficits are discussed.
This study was funded by the University Grants Commission of India.
An erratum to this article can be found at 相似文献
113.
Recent years have witnessed growing research interest in citizen perceptions of the police. This was likely the result of the community policing movement, which sought to strengthen ties between citizens and the police, as well as to concerns about the legitimacy of the police. Most of this research focused on police agencies in the United States, and little research had been conducted on citizen perceptions of the police in Asian countries. This study sought to fill this void through an analysis of citizen perceptions of the police in South Korea. To address these issues, telephone interview survey data gathered from 11,500 randomly selected citizens were obtained in the rapidly industrializing country, South Korea. Several sets of multiple-regression models were estimated to assess the effect of urbanization, demographics, evaluations of police services, and perceived corruption on citizen satisfaction with police. The results suggested that citizens in small to mid-sized cities and large urban cities were less satisfied with police than were residents of rural areas. In addition, age, evaluations of police service, and perceptions of corruption were related to citizen satisfaction. The results were discussed in comparison to previous research in Asia and the United States and other Western countries. 相似文献
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Robert S. McLaren Martin G. Ensenberger Bruce Budowle Dawn Rabbach Patricia M. Fulmer Cindy J. Sprecher Joseph Bessetti Terri M. Sundquist Douglas R. Storts 《Forensic Science International: Genetics Supplement Series》2008,2(4):257-273
Several laboratories have reported the occurrence of a split or n − 1 peak at the vWA locus in PowerPlex® 16 and PowerPlex® ES amplification products separated on 4- and 16-capillary electrophoresis instruments. The root cause of this artifact is post-PCR reannealing of the unlabeled, unincorporated vWA primer to the 3′-end of the tetramethylrhodamine (TMR)-labeled strand of the vWA amplicon. This reannealing occurs in the capillary post-electrokinetic injection. The split peak is eliminated by incorporation into the loading cocktail of a sacrificial hybridization sequence (SHS) oligonucleotide that is complementary to the vWA primer. The SHS preferentially anneals to the primer instead of the TMR-labeled strand of the vWA amplicon. In addition, the n − 10/n − 18 artifact that may be seen at the vWA locus was determined to be due to double-stranded amplicon formed post-electrokinetic injection into the capillary. This was also eliminated by adding in two Complementary Oligo Targets (COT1 and COT2) in addition to the SHS oligonucleotide into the loading cocktail. These three oligonucleotides are complementary to the 33 bases at the 5′-end of the unlabeled vWA amplicon strand and the 60 bases at its 3′-end and therefore compete for hybridization to the TMR-labeled amplicon strand. Incorporation of these three oligonucleotides in the Internal Lane Standard 600 (ILS600) eliminate both the split peak and n − 10/n − 18 artifact in PowerPlex® 16 and PowerPlex® ES amplification products without affecting sizing of alleles at the vWA locus or any locus in the PowerPlex® 16, PowerPlex® Y, PowerPlex® ES, AmpFlSTR® Profiler Plus® ID, AmpFlSTR® Cofiler®, and AmpFlSTR® SGM Plus® kits. 相似文献
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There is a growing interest within universities in the operation of state and local governments, and in the services they provide. An example of this interest is the Program for Urban and Policy Sciences (UPS) at the State University of New York at Stony Brook.Since its inception two years ago, it has been the operating policy of the Program to direct its principal research activities to real and immediate problems facing state and local governments in the New York area. In each of the collaborative efforts undertaken with an outside agency, we have seen our role as that of both problem analysts and catalytic agents for bringing about change. This means our faculty and students actively participate in the policy formulation and policy implementation processes. A case study of a cooperative effort undertaken with the Environmental Protection Administration of New York City illustrates these ideas.We believe that a successful university program should combine research with real world experience; the university should encourage the faculty to broaden the scope of their activities; and students, particularly those from minorities, should be trained for professional careers as planning and program analysts.Work reported in this paper has been supported by the National Science Foundation under grant GI-5. A similar version of the paper was presented at the American Political Science Association Conference, September 6–11, 1971, Chicago, Illinois and at the ORSA Conference, October 28, 1971, Anaheim, California. 相似文献
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