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861.
An underlying assumption of proportional hazards models is that the effect of a change in a covariate on the hazard rate of event occurrence is constant over time. For scholars using the Cox model, a Schoenfeld residual‐based test has become the disciplinary standard for detecting violations of this assumption. However, using this test requires researchers to make a choice about a transformation of the time scale. In practice, this choice has largely consisted of arbitrary decisions made without justification. Using replications and simulations, we demonstrate that the decision about time transformations can have profound implications for the conclusions reached. In particular, we show that researchers can make far more informed decisions by paying closer attention to the presence of outlier survival times and levels of censoring in their data. We suggest a new standard for best practices in Cox diagnostics that buttresses the current standard with in‐depth exploratory data analysis.  相似文献   
862.
对预警信息的科学调控能够有效提升危机预警工作质量。本文以人口安全预警系统为例,建构了预警系统参与要素协作模型和预警临界值选择模型。在此基础上,从信息要素与信息流角度分析了预警系统的整体构成、要素协作机制与信号表达机制,并进而反思了危机预警中的政府信息管理角色和信息调控模式,提出了提升预警预测精度和时间效率的途径与方法。  相似文献   
863.
The balance between majority rule and minority rights is a central issue in the design and operation of democratic institutions and remains a contested issue in debates of policy‐making processes. Remarkably, public attitudes about this balance are not subjected to scholarly investigation. In this article, we report the findings of the first survey experiment in which the American public's attitudes about majority rule and minority rights in legislative bodies are explored. We find robust support for both majority rule and minority rights, discover that only a few Americans distinguish between the US House of Representatives and Senate in the application of these principles, and demonstrate that views of majority rule and minority rights can be moved once we introduce respondents to the partisan implications of procedural rules. Moreover, with conflicting theoretical expectations about the effect of political sophistication on attitudes about majority rule and minority rights, we find that higher levels of political sophistication are associated with stronger partisan effects on attitudes about the balance between majority rule and minority rights in Congress.  相似文献   
864.
Nicotine is a potent neurotoxin alkaloid and is used in e‐cigarette liquid. The LC/MS/MS method was linear over 0.01–1.0 mg/L (r2 = 0.992–0.995). Limit of detection and limit of quantitation were 0.001 mg/L (S/N = 3) and 0.003 (S/N = 10). The inaccuracy and imprecision were <13.2%. The recoveries were >99.3%. A 39‐year‐old dentist was found dead lying on the floor under the couch in his dental clinic. The concentration of nicotine, cotinine, and trans‐3′‐hydroxycotinine (heart blood/peripheral blood) was analyzed as follows: 87.2/85.2 mg/L (ratio 1.0), 1.4/1.1 mg/L (ratio 1.3), and 0.012/0.0089 mg/L (ratio 1.3), respectively. The concentration of nicotine was determined to be 6734.8 mg/kg in gastric contents and 7262.0 mg/L in remaining e‐liquid. Only, high concentration of nicotine was detected in the gastric contents as well as the two pieces of evidence collected from the death scene. This fatal case resulted from oral ingestion of e‐cigarette liquid. It is estimated that at least 714 mg of nicotine was orally ingested.  相似文献   
865.
Local governments commonly pursue environmental objectives that exceed state and federal minimum requirements. Although research informs our understanding of factors that lead cities to adopt such policy goals, the underlying mechanisms employed to achieve them are not well understood. This article examines factors that drive the choice of policy instruments that cities use to pursue local environmental objectives. The literature links the structure of the local governing body, characteristics of the community and target populations, and the nature of the policy problem to instrument selection. Building on this, the authors model the dynamics shaping cities' use of regulations, financial incentives, or combination thereof, to pursue a variety of different environmental objectives. Results indicate that community racial composition and political leaning influence instrument choice when policy targets the public at large. Alternatively, when policy targets particular stakeholder groups, such as developers, the characteristics of the local governing body are of greater importance.  相似文献   
866.
Sounman Hong  Nara Park 《管理》2019,32(3):421-439
Although administrative reorganization has been a major political instrument in many democracies, there has been limited research on its effects. Aiming to address this gap, this study examines the reorganization of Korean government ministries, specifically, the impact of reorganization in the form of a merger of ministries performing interrelated but dissimilar functions. Examining the salience of policy issues expressed in official government press releases during the 12‐year period from 2001 to 2012, we found that administrative reorganization in the form of a merger has a significant impact on the relative salience of government policy agendas. Specifically, the interrupted time series estimates indicate that the salience of science and technology policy issues (in relation to education policy issues) decreased by approximately 12% to 17% following the dissolution of the Ministry of Science and Technology. We explain this finding based on the bounded rationality view of bureaucratic information processing.  相似文献   
867.
Journal of Youth and Adolescence - Adolescents’ own vocational aspirations and those of parents for their adolescent children play significant roles in adolescents’ development. The...  相似文献   
868.
Asian Journal of Criminology - Numerous studies have analyzed the relationship between disorder and fear of crime, but few have focused on the impact of policing against disorder on fear of crime....  相似文献   
869.
在全面建设小康社会过程中,必须发挥工人阶级的创造作用,同时要努力提高职工队伍的整体素质.工会要围绕提高职工思想道德素质、科学文化素质和健康素质开展工作.  相似文献   
870.
Recently, adulterated supplements with phosphodiesterase-5 inhibitors (PDE-5i) have frequently observed. New synthetic analogues obtained from the chemical modification of parent compounds are frequently found in illicit products despite continuous efforts to inspect for these adulterants. A rapid and accurate method based on quadrupole-Orbitrap mass spectrometry was developed for simultaneously confirming and quantifying 85 PDE-5i and derived analogues present in illicit products for erectile dysfunction (ED). Common ions of PDE-5i according to their similar structures were proposed based on MS/MS fragmentations. These common ions could be an important diagnosis of their presence targets or new emerging analogues in supplements. Several validation parameters were employed, resulting in a limit of detection and quantification of 0.09–8.55 ng/mL and 0.24–17.10 ng/mL, respectively. The linear correlation coefficient (r2) was higher than 0.995, and mean recoveries of target compounds were in the range of 82–118%. A total of 187 illicit products, obtained from on/offline markets over a period of 3 years (2015–2017), were screened by the established method. Approximately 53% of them were adulterated with PDE-5i or derived analogues at concentrations of 0.1–726.0 mg/g in the illicit products. In the interests of public health, this study describes a rapid and accurate method to determine PDE-5i and new emerging analogues in adulterated products.  相似文献   
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