Last-ditch attempt to improve the EU patent system

The European Commission has proffered a compromise seeking torevitalize the ongoing debate on the patent system in Europeby enabling Member States to reach a consensus.     

Sex offender notification: An exploratory assessment of state variation in notification processes

Prior research suggested that when community members are notified that a sex offender is residing in their neighborhood they are likely to engage in precautionary behavior to prevent potential victimization. Since states employ different processes in notifying community members of the presence of a sex offender, it is important to examine the advantages and disadvantages of the various notification processes. The current exploratory study compared the proactive sex offender notification process in Hamilton County, Ohio, with the passive notification process in Jefferson County, Kentucky. Not surprisingly, study findings indicated that the proactive sex offender notification process used in Ohio resulted in better community dissemination of information.     

Jersey trusts and foreign divorce proceedings: The H Trust (2007) JRC 187

This is a second and important judgment in the H Trust litigation,which was first before the Royal Court in April 2006. At thathearing, the Royal Court directed the Jersey resident trusteeof the H Trust not to take any part in English divorce proceedingsbetween a husband and wife, both of whom were beneficiariesunder the H Trust, but to provide full information to the partiesfor use in the English High Court. The husband was the settlorof the H Trust. The Royal Court also encouraged the trusteeto assist in giving effect to any reasonable arrangement     

The urban household in Russia and the Soviet Union, 1900–2000: Patterns of family formation in a turbulent century

Starting from census data on co-residence and household composition, the authors analyse principles of family organisation and family formation in twentieth-century urban Russia and the Soviet Union. The article uses an adapted version of the classification of households developed by Peter Laslett and Eugene Hammel to study variation in household structure for successive population censuses. Changes in this variation between cross-sections are explained with the help of additional quantitative and qualitative data and are linked to the fundamental demographic, social and economic shifts which took place in Russian society in the course of the twentieth century. The article finds a family system characterised by a tendency towards nuclear family formation, but incorporating a fairly stable element of household extension. Co-residence of three generations was both an answer to a perennial housing problem and offered important advantages in the sphere of childcare and care for the elderly. Variation and fluctuation in household structure are found to be most pronounced during the turbulent first half of the century. After a period of stability during the post-war decades of Soviet rule, post-Soviet transformations provoke new changes.     

Identifying reliable ions for the statistical differentiation of structurally similar fentanyl analogs

Definitive identification of fentanyl analogs based on mass spectral comparison is challenging given the high degree of structural and, hence, spectral similarity. To address this, a statistical method was previously developed in which two electron-ionization (EI) mass spectra are compared using the unequal variance t-test. Normalized intensities of corresponding ions are compared, testing the null hypothesis (H₀) that the difference in intensity is equal to zero. If H₀ is accepted at all m/z values, the two spectra are statistically equivalent at the specified confidence level. If H₀ is not accepted at any m/z value, then there is a significant difference in intensity at that m/z value between the two spectra. In this work, the statistical comparison method is applied to distinguish EI spectra of valeryl fentanyl, isovaleryl fentanyl, and pivaloyl fentanyl. Spectra of the three analogs were collected over a 9-month period and at different concentrations. At the 99.9% confidence level, the spectra of corresponding isomers were statistically associated. Spectra of different isomers were statistically distinct, and ions responsible for discrimination were identified in each comparison. To account for inherent instrument variations, discriminating ions for each pairwise comparison were ranked based on the magnitude of the calculated t-statistic (t_calc) value. For a given comparison, ions with higher t_calc values are those with the greatest difference in intensity between the two spectra and, therefore, are considered more reliable for discrimination. Using these methods, objective discrimination among the spectra was achieved and ions considered most reliable for discrimination of these isomers were identified.