Autoerotic asphyxial death initially misinterpreted as suicide and a review of the literature.

Death during autoerotic activities is of special concern to law enforcement officials, medical examiners, the family of the decedent, and society in general. As in the probing of any violent demise, accurate identification, management, and preservation of all physical evidence; complete photographic documentation of the scene and the body; reconstruction of the scene; and interviews with the family and acquaintances (psychological autopsy) are mandatory for proper study, evaluation, and interpretation of the case. Because of a lack of knowledge on the part of many people, including professionals, about these activities and the fact that many autoerotic fatalities share common characteristics with suicide and homicide, these cases are often misinterpreted. The authors present a case of autoerotic accidental asphyxial death which was initially misinterpreted as suicide.     

巴西--发展中大国及其国际战略

这是本刊增设的一个栏目。顾名思义,“大使论坛”就是大使们的论坛。它是由中国社会科学院国际合作局与社科院其他研究所主办的一个论坛,而2005年8月18日由中国社会科学院国合作局和拉美所主办的“巴西的大国地位与大国战略”是首届大使论坛。在首届大使论坛上,巴西驻中国大使路易斯·奥古斯托·德卡斯特罗·内维斯先生作了题为《巴西———发展中大国及其国际战略》的报告并回答了与会者提出的问题。     

The liberian civil war: new war/old war?

The Liberian civil war has been portrayed as a primary example of ‘new wars’, drawing attention both to the economic motives and the global character of the conflict. However, to focus excessively on material explanations and greed-inspired motivations of actors may lead to one-sided explanations of conflict. This article suggests that there is little ‘new’ about the Liberian war. Rather, it can best be understood as a violent expression of the tendencies, organisation and attitudes towards identity, society and class that have underpinned Liberia since its formation in the 19th century. The ‘new war’ literature helps us to understand one important dimension of the Liberian conflict. However, too much emphasis on this dimension may also lead scholars and policy-makers to neglect the ideational aspect of conflict. These are of immense importance to a full understanding of civil war and its dynamics.     

The role of Salvadorean NGOs in post-war reconstruction

The Peace Agreement signed recently between the Government and FMLN guerrillas in El Salvador marks the end of a decade of civil war. As both sides of the conflict and the international donor community begin to add up the financial costs of reconstruction, the human, social and psychological costs are carried mainly by the poor of El Salvador. Social organisations and NGOs who became strategists of survival now face the challenge of transforming their accumulated experience into alternative proposals for the building of a more just society and a prosperous nation. This article explores the practical complexities of transition from war to peace; and from emergency aid to sustainable development based on the participation of communities, social organisations, NGOs, and international agencies; and the challenges of building on their experience.     

The post mortem alterations of myofibrilar proteins and adenosintriphosphatase activities of the skeletal muscles (author's transl)]

Immediately after the death of rabbits and at different times within 48 hours, we took out a part of the psoas muscle, from which we made myofibrilar preparations. The carcasses providing the muscle samples were held at two different temperatures. One group was held for 48 hours at 25 degrees C, imitating room temperature. The other group was held for 12 hours at 25 C degrees and at 25 C degrees and 12 hours at 10 C degrees, imitating daily temperature changes. Each myofibrilar sample was subjected to SDS-polyacrylamide gel electrophoresis. In addition we determined the Ca++ activated and the EGTA inhibited ATPase specific activity of the myofibrils. We found that within 48 hours the myofibrilar proteins were subjected to some characteristic proteolytic changes, which were dependant on the environmental temperature. The most interesting change was found in carcasses held constantly at 25 C degrees for 48 hours, where the EGTA inhibited ATPase activity was increased to about seven times its initial value, reflecting impairment of the troponin complex.     

Alcohol,illicit drugs and medicinal drugs in fatally injured drivers in Spain between 1991 and 2000

The aim of this study was to assess the presence of alcohol, illicit drugs and medicinal drugs among Spanish drivers involved in fatal road accidents between 1991 and 2000. Samples were obtained for 5745 drivers killed in road accidents from January 1991 to December 2000. Of the samples, 91.7% represented males and 8.3% females; 40.7% were under 30 years of age, 31.9% were under 31-50 years of age, 19.5% were over 51 years of age, and for 7.9% the age was unknown. Between 1991 and 2000, some type of psychoactive substance was detected among 50.1% of those drivers killed in road accidents, this being mainly alcohol (43.8%) and, less frequently, illicit drugs (8.8%) and medicinal drugs (4.7%). In all the cases, in which alcohol was detected, combined use with other substances accounted for only 12.5%, whilst in the case of illicit and medicinal drugs, figures representing combined use with other substances were 75.6% for the former and 65.8% for the latter. For one in every three cases (32.0%), a blood alcohol level over 0.8 g/l was recorded; cocaine (5.2%), opiates (3.2%) and cannabis (2.2%) were the three illicit drugs most frequently detected. Among medicinal drugs, were benzodiazepines (3.4%), anti-depressant drugs (0.6%) and analgesics (0.4%). The results show the frequent presence of psychoactive substances, particularly alcohol, among Spanish motor vehicle users involved in fatal road accidents. It should be pointed out that illicit and medicinal drugs in combination with other substances were a common feature.     

One-step liquid-liquid extraction of cocaine from urine samples for gas chromatographic analysis

An improved technique for cocaine extraction from urine samples for gas chromatographic (GC) analysis is described. Employing a simple liquid-liquid extraction (LLE) of cocaine with a mixture of ethyl ether:isopropanol (9:1) the method presents a mean recovery of 74.49%. Limit of detection (LOD) and limit of quantification (LOQ) were 5 and 20 ng/ml, respectively. The method is highly precise (coefficient of variation (CV) <8%) and linear from 20 to 2000 ng/ml. It can he applied to detect the presence of cocaine in urine as a marker of its recent use in drug abuse treatment protocols.     

A study on the effects of degradation and template concentration on the amplification efficiency of the STR Miniplex primer sets

In forensic DNA analysis, the samples recovered from the crime scene are often highly degraded leading to poor PCR amplification of the larger sized STR loci. To avoid this problem, we have developed STR markers with redesigned primer sequences called "Miniplexes" to produce smaller amplicons. To assess the effectiveness of these kits, we have tested these primer sets with enzymatically degraded DNA and compared the amplifications to a commercial kit. We also conducted sensitivity and peak balance studies of three Miniplex sets. Lastly, we report a case study on two human skeletal remain samples collected from different environmental conditions. In both types of degraded DNA, the Miniplex primer sets were capable of producing more complete profiles when compared to the larger sized amplicons from the commercial kit. Correct genotypes were obtained at template concentrations as low as 31 pg/25 microL. Overall, our data confirm that our redesigned primers can increase the probability of obtaining a usable profile in situations where standard kits fail.