Sample Mining and Data Mining: Combined Real-Time and Retrospective Approaches for the Identification of Emerging Novel Psychoactive Substances

Novel psychoactive substances (NPS) are synthetic drugs that pose serious public health and safety concerns. A multitude of NPS have been identified in the United States, often implicated in forensic investigations. The most common and effective manner for identifying NPS is by use of mass spectrometry and the true utility lies within nontargeted acquisition techniques. During this study, a liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) assay was developed, validated, and implemented for forensic toxicology testing. A SCIEX TripleTOF™ 5600 + with SWATH^® acquisition was used. Resulting data were compared against an extensive library database containing more than 800 compounds. The LC-QTOF-MS assay was applied to the reanalysis of biological sample extracts to discover emergent NPS. More than 3,000 sample extracts were analyzed, and more than 20 emerging NPS were detected for the first time. Among these were isopropyl-U-47700, 3,4-methylenedioxy-U-47700, fluorofuranylfentanyl, N-methyl norfentanyl, 2F-deschloroketamine, 3,4-methylenedioxy-alpha-PHP, eutylone, and N-ethyl hexedrone.     

Denouncing or Supporting the Chilean Dictatorship in West Germany? Local Associations of Solidarity and Their Transnational Networks Since the 1970s

After the coup of 11 September 1973 in Chile, the international solidarity movement, including Chilean exiles, that flourished on a global level not only tried to help the victims of the military junta with their material needs, but also carried out advocacy work in order to denounce the crimes committed by the regime and to collect documents and information that could be used as evidence in future court cases. At the same time, the junta also drew on a network of foreign supporters, including European ones. In order to analyze theses networks’ campaigns to denounce (or cover) the crimes perpetuated and their ongoing judicial and memory struggles in Latin America and Europe, from the 1970s until today, this article provides a study of mobilizations between Chile and West Germany, namely of the Forschungs- und Dokumentationszentrum Chile-Lateinamerika in West Berlin, the West German section of Amnesty International and the supporters of the German sect in Chile “Colonia Dignidad”.     

The Longitudinal Role of Self-Concept Clarity and Best Friend Delinquency in Adolescent Delinquent Behavior

Journal of Youth and Adolescence - Adolescence tends to be characterized by a temporary peak in delinquent behavior, and friends in particular play a key role in the initiation and the development...     

Discourses on countering violent extremism: the strategic interplay between fear and security after 9/11

This article explores the construction of extremism in media discourse, the factors driving specific constructions and the implications of these constructions for counterterrorism policy. We contend that extremism has predominantly and increasingly been framed as a security issue. This article explores the implications of this practice through the framework of securitisation. We measure the average intensity of security framing in 38,616 articles found in three major US newspapers, New York Times, Wall Street Journal and Los Angeles Times, between 20 January 1993 and 19 January 2017 comprising the Clinton, Bush and Obama presidencies, and look at factors influencing the shift in intensity over time. Through our analysis, we show that it is possible to return to a pre-9/11 discourse but that the confluence of real-world events and the strategic choices of political actors have so far prevented this from fully occurring. We then explore the effect of securitisation on public perceptions of the threat from terrorism, finding that increases in the intensity of security framing artificially increases the public’s worry about becoming a victim of terrorism. We conclude by discussing implications for the communication of counterterrorism policy and the requirements for an after, after 9/11 approach     

The star of David in a cedar tree: Jewish students and Zionism at the American University of Beirut (1908–1948)

The American University of Beirut's emergence as a hub of Arab national and cultural identity in the first half of the twentieth century has been well documented by historians. The simultaneous Zionist presence on campus has been largely overlooked. Zionist ideas were predominantly promoted by Palestinian Jewish students who formed a small but vocal minority at AUB prior to 1948. Faculty and non-Jewish students also regularly collaborated with and traveled to Zionist institutions in Palestine for academic, athletic, and leisure purposes. For Arab students on campus, therefore, Zionism was not an abstract concept, but rather a national identity embodied by fellow classmates and friends on campus. As the conflict in Palestine increased in the 1930s and 1940s, so too did political activism and tensions on campus between Zionist and Arab nationalist students. This article analyzes this unique period of exchange, collaboration, and friction at AUB, which came to a swift end with the outbreak of the 1948 War. By focusing on the interactions between Arab and Zionist Jewish students at AUB, I seek to extend the ‘relational’ approach towards Jewish-Arab contact beyond Palestine's borders.     

The Five Cs Model of Positive Youth Development: A Longitudinal Analysis of Confirmatory Factor Structure and Measurement Invariance

The understanding of positive development across adolescence rests on having a valid and equivalent measure of this construct across the breadth of this period of life. Does the Positive Youth Development (PYD) construct based on the Five Cs model have satisfactory psychometric properties for such longitudinal measurement invariance? Using longitudinal data derived from the 4-H Study of PYD, we assessed 920 youth (61.6% female) from a racially and ethically diverse sample (67.3% European American) who participated in three waves (Grades 8–10) of data collection. Building on prior findings that the Five Cs (i.e., Competence, Confidence, Connection, Character, and Caring) model of PYD was a robust measure that could be assessed comparably during early adolescence, we tested a hierarchy of second-order confirmatory factor analysis models to assess the extent to which PYD can be measured equivalently across middle adolescence. Evidence was found for strict measurement invariance across three measurement occasions, including equivalence of first-order and second-order factor loadings, equality of intercepts of observed variables, and equality of item uniqueness and disturbances of the first-order factors. These results suggest that PYD can be measured in the same way across measurement occasions, a prerequisite for the study of development. Implications for research and application of being able to measure PYD equivalently across adolescence are discussed.     

"A jazzed and patchwork modern": "future" girls and modern masculinities in the early popular romances of Berta Ruck

As a best-selling writer of popular romances during the first half of the twentieth century, Berta Ruck (1878-1978) has been characterised as a producer of 'omelettes of frivolity and sweetness' whose appeal was confined to adolescent girls and the servant classes. Closer attention to some of the early novels and to her own evaluation of her work, however, reveals her attempts to confront and articulate the impact of societal change upon a generation whose world was being irrevocably altered by the Great War and its aftermath. Her almost forensic attention to local detail and her treatment of contemporary questions of gender identity make her a compelling chronicler of the period and lend credibility to her claims of a broader readership than that generally associated with the genre.     

Not All Housing GSEs Are Alike: An Analysis of the Federal Home Loan Bank System and the Foreclosure Crisis

While the financial crisis of 2008 ultimately affected the range of U.S. financial institutions, it began with practices in home ownership finance. The Federal Home Loan Bank (FHLBank) System was the first instrumentality created by the U.S. government, in 1932, to sustain affordable home ownership finance. In this article, the authors ask what role, if any, the FHLBanks played in the subprime lending and securitization practices that precipitated the current crisis. The authors analyze publicly available FHLBank financial data in terms of a framework focused on the System's assets: advances; mortgage loans acquired from members; and investments, particularly in mortgage-backed-securities. They conclude that the FHLBanks did not contribute significantly to problematic practices. Nonetheless, they recommend consideration of three reforms to the FHLBanks to ensure a return to effective regulation and responsible, affordable home ownership finance.     

Leviathan resists: the endogenous relationship between privatization and firm performance

Using a panel dataset of privatized cement firms in Turkey, this paper models and finds support for the simultaneous relationship between privatization and firm performance. It is found that favorable short-run performance, weak market potential, higher employment, lower socio-economic development, concentrated voter preferences, and weaker representation of right-wing parties in the firms’ locality delay the timing of privatization. The paper also finds that privatization increases output in the medium-term by reducing the labor stock and promoting the adoption of more advanced technology, such that production shifts from constant to decreasing returns to scale.