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Influenza A virus infection complicated by fatal myocarditis 总被引:4,自引:0,他引:4
Nolte KB Alakija P Oty G Shaw MW Subbarao K Guarner J Shieh WJ Dawson JE Morken T Cox NJ Zaki SR 《The American journal of forensic medicine and pathology》2000,21(4):375-379
Influenza virus typically causes a febrile respiratory illness, but it can present with a variety of other clinical manifestations. We report a fatal case of myocarditis associated with influenza A infection. A previously healthy 11-year-old girl had malaise and fever for approximately 1 week before a sudden, witnessed fatal collapse at home. Autopsy revealed a pericardial effusion, a mixed lymphocytic and neutrophilic myocarditis, a mild lymphocytic interstitial pneumonia, focal bronchial/bronchiolar mucosal necrosis, and histologic changes consistent with asthma. Infection with influenza A (H3N2) was confirmed by virus isolation from a postmortem nasopharyngeal swab. Attempts to isolate virus from heart and lung tissue were unsuccessful. Immunohistochemical tests directed against influenza A antigens and in situ hybridization for influenza A genetic material demonstrated positive staining in bronchial epithelial cells, whereas heart sections were negative. Sudden death is a rare complication of influenza and may be caused by myocarditis. Forensic pathologists should be aware that postmortem nasopharyngeal swabs for viral culture and immunohistochemical or in situ hybridization procedures on lung tissue might be necessary to achieve a diagnosis. Because neither culturable virus nor influenza viral antigen could be identified in heart tissue, the pathogenesis of influenza myocarditis in this case is unlikely to be the result of direct infection of myocardium by the virus. The risk factors for developing myocarditis during an influenza infection are unknown. 相似文献
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The forensic analysis of soil organic by FTIR 总被引:3,自引:0,他引:3
In order to elucidate the discriminating power of various soil analytical techniques, over 100 soils samples were analyzed using conventional analysis (i.e., color, percent organic and density gradient) and a novel FTIR technique. The FTIR technique involves collecting a spectrum of a soil sample that has been oxidatively pyrolysed, and therefore all organic have been degraded. This spectrum is subtracted from the spectrum of the same sample that contained the organic prior to pyrolysis. This resultant IR spectrum represents the organic portion of the sample. The use of organic components increases the discrimination in soils that are otherwise similar. We have illustrated the usefulness of this technique by selecting four soil samples, which have identical Munsel color values but can be discriminated by subtractive ETIR. We propose that the ETIR spectra of the organic portion of soil serves a useful purpose in forensic investigations. 相似文献
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Since the end of the Cold War, globalization has become the
centralphenomenon in world politics. Civilizations, once geographically
based,are now loosened from fixed space, as migration of peoples andof ideas
has accelerated. A focus on the dimensions of intersubjectivitywill give some
understanding both of differences among civilizationsand on transformations
of civilizations. Attention is thus givento different forms of substantive
economies, to historical dominanceand subordination of civilizations and to
the reawakenings ofcultures; to what Sorokin called the sensate and
ideationaltypes of consciousness and to different forms of spirituality,and
to relative orientations toward time and space. Two propositionsare implicit
in a concern for civilizations: (i) that thereare alternatives for the human
future, and (ii) that if differentcivilizations do coexist, the problem of
mutual comprehensionbecomes paramount for the maintenance of world order. The
implicationsfor a research program are to study civil societies as the
sourcesof intersubjective meanings, the maintenance of the biosphereas the
basic material condition of existence of all civilizations,and world
governance as the modus vivendi of a plural world. 相似文献
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