Screening for Corticosteroid Adulterants in Korean Herbal Medicines

The objective of this study was to determine the presence of corticosteroids in illegal herbal medicines using ultra‐high‐performance liquid chromatography–tandem mass spectrometry. We collected 212 herbal medicine samples that were advertised as being effective for treatment of joint pain and bone aches. Samples were from the Korean commercial market during a span of four years (2010–2013), and the method was validated. The limits of quantification ranged from 0.47 to 15.0 ng/mL, and recoveries ranged from 80.6% to 119.5%. The intra‐ and interday precision ranged from 0.18% to 8.82% and from 0.09% to 8.96%, respectively. Among the samples, three samples (1.4%) were identified as adulterants. Dexamethasone was the only compound detected in the adulterated products. As the corticosteroid–adulteration of herbal medicines may become a major problem and lead to side effects, the continued development of screening procedures for herbal medicines is critical.     

Affect-ing discourse: towards an embodied discourse analytics

The contemporary retheorisation of affect is impacting on an increasingly wide range of disciplines/inter-disciplines in the human sciences. Of particular relevance for this paper are, on the one hand, the emphasis on embodiment and, on the other, the ideas of “flow”, “intensity” and “contagion”. Together, these challenge traditional views of affect as equivalent to emotion, emanating from the self and ending at the boundary of the self. Discourse studies has not yet been significantly influenced by the “affective turn” now taking place within social and cultural theory. It has largely maintained, albeit implicitly, the traditional view of affect. Yet, if all human interaction is inflected with affect, in the sense indicated above, a different model of discourse seems called for. This paper aims to make a contribution to the development of a new “affect-ed” discourse analytics by identifying a variety of linguistic and discursive phenomena that could contribute to such a project. We draw primarily on the work of linguistics, bringing to notice a range of phenomena that may be unfamiliar either because of their technicality or because of the problematic status of linguistics in much cultural theory. The paper proceeds via a brief genealogical account of current affect theory to note a range of language phenomena that have been or can be read in terms of individual feeling and suggests an analysis of several forms of interaction re-read in terms of affective contagion. This section of the paper constitutes a preliminary inventory of components of an affect-ed discourse analytics.     

Creating an enabling environment for housing: Recent reforms in Mexico

Abstract

A recent World Bank policy statement on housing advocates the reform of government policies, institutions, and regulations to enable housing markets to work more efficiently. The policy statement identifies several instruments that governments can use to address housing market constraints, and to improve the performance of the housing sector as a whole, while paying particular attention to the needs of the poor.

In recent years, the government of Mexico has employed many of the enabling instruments described in the World Bank's housing policy statement. This article reviews the role of housing in the Mexican economy and the major reforms that the Mexican government has implemented to improve the operation of the housing market so that private lenders and home builders can play an expanded role in addressing the country's housing needs. The World Bank has supported the government's reform program, and since 1985 it has lent more than $1.2 billion to Mexico for low‐income housing projects.     

Achieving Economic Self-Sufficiency Through Housing Assistance: An Assessment of a Self-Sufficiency Program of the Housing Authority of Champaign County,Illinois

ABSTRACT

This study examines the early impact of a Local Self-Sufficiency (LSS) program of the Housing Authority of Champaign County (HACC), Illinois, on recipients’ total annual household income and earnings, and employment. In 2013, HACC, through LSS, mandated work requirements for households with working-age, able-bodied adult members and imposed sanctions on those who did not meet the program requirements. We find that, between 2012 and 2014, the LSS program led to an average increase of $2,283 in earnings for an individual household. In aggregate, this allowed HACC to serve an additional 98 (9%) LSS-eligible households for a year. Also, LSS-eligible households experienced an increase in the employment–adult ratio by 11.6 percentage points. The LSS program also had a larger impact for more economically disadvantaged households with no prior work history.     

Collaborative Decision Making in Urban Regeneration: A Complex Adaptive Systems Perspective

In this paper we examine the processes and participants in urban regeneration with a view to identifying the nature of collaborative decision making in a particular policy arena. Recognizing that the environment in which public managers operate is a complex nexus of agency, structure, environment, and feedback processes, we apply a complex adaptive systems (CAS) framework comprised of agents, rules, outcomes, decision factors, and processes within the public policy arena—in this case urban regeneration in Ireland—in order to explore collaborative decision making in the public domain. The CAS framework draws particular attention to self-organizing features of the system under study and to the emergence of agents, order (“rules”), and outcomes. Using this framework, we found that three of the six urban regeneration projects (“systems”) in our study featured the emergence of project specific agents as important facilitators of collaborative decision making and as key contributors to the expansion of system scope.     

Disconnection and resistance: anti-terrorism and citizenship in the UK

The corroding impacts of anti-terrorism measures on citizenship have been much discussed in recent years. Drawing on qualitative research from the UK, this article argues that citizens do indeed frequently feel that aspects of citizenship – such as rights, duties, identity claims and the ability to participate in the public sphere – have been significantly dampened by developments in this policy area. At the same time, however, participants in our research also articulated a number of strategies through which they or others have sought to resist the logics, exercise and impacts of anti-terrorism powers. These included voicing explicit opposition to particular measures, resisting ‘outsider’ or ‘victim’ subject positions, and a refusal to withdraw from established forms of political engagement. Whilst such resistance should not be overstated, we argue that these strategies emphasise the co-constitutive rather than linear relationship between public policy and citizenship. Anti-terrorism powers do indeed impact upon citizenship claims, for instance in the curtailment of formal rights. Equally, the everyday, lived, experiences and practices of citizenship contribute to, and help shape, the perceptions and understandings of anti-terrorism policy from within the citizenry     

Improved gas chromatography-negative ion chemical ionization tandem mass spectrometric method for determination of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in hair using mechanical pulverization and bead-assisted liquid-liquid extraction

A gas chromatography-negative ion chemical ionization tandem mass spectrometric (GC-NCI-MS/MS) method was developed and validated for the determination of 11-nor-Δ(9)-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) in human hair. After decontamination, hair samples were weighed (25mg), mechanically pulverized with a bead mill, and incubated in 0.7 mL of 1.0M sodium hydroxide at 95 °C for 30 min. Bead-assisted liquid-liquid extraction was performed with n-hexane:ethyl acetate (9:1, v/v), a method developed in our laboratory. The extract was evaporated to dryness, derivatized with pentafluoropropanol and pentafluoropropionic anhydride, and analyzed by GC-MS/MS in the negative ion chemical ionization mode using methane as the reagent gas. The linear ranges were 0.05-10.0 pg/mg for THC-COOH with the coefficient of determination (r(2) = 0.9976). The intra-day and inter-day precisions were within 1.7 and 13.8%, respectively. The intra-day and inter-day accuracies were -4.8 to 10.0% and -3.9 to 3.8%, respectively. The limit of detection and quantification were 0.015 and 0.05 pg/mg, respectively. The recoveries were in the range of 79.4-87.1%. The results indicate that the proposed method is simple, rapid, accurate, and precise for determination of THC-COOH in hair. The method identified THC-COOH in hair specimens from suspected marijuana abusers.