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51.
This paper presents a disposable biosensor to detect serum alcohol concentration. The proposed biosensor is fabricated using the cross-linking method to immobilize Alcohol Dehydrogenase (ADH) and Nicotinamide Adenine Dinucleotide (NAD(+)) on the screen-printed electrode modified with Meldola's Blue (MB) absorbed on Nafion. It is based on the electrocatalytic properties of MB as an electron transfer mediator, which can catalyze the oxidation of NADH to NAD(+) at a low oxidizing potential, thus avoiding interferences due to the presence of oxidizable substances in the real serum samples. The biosensor response for alcohol is investigated in terms of pH, buffer solution, temperature and some interferents. It presents the good specificity, reproducibility, stability, accuracy and provides a fast response. The biosensor has been satisfactorily used for the measurement of serum alcohol. 相似文献
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This paper examines two recent examples of compulsory licensing legislation: one globally embraced regime and one internationally controversial regime operating under the same WTO rules. In particular, we consider Canadian legislation and the use of compulsory licensing for HIV/AIDS drugs destined for a developing country. This is then contrasted with the conditions under which Thai authorities are pursuing compulsory licenses, the outcomes of their compulsory licenses, as well as the likely impact of the Thai policy. Finally, we construct a rubric to evaluate characteristics of a successful regime. This is used to analyze the Canadian and Thai regimes and frame the expected implications of each national policy. It is hoped that the assessment will guide changes to compulsory licensing design to ensure that legitimate regimes are embraced while illegitimate ones are disallowed. 相似文献
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Elisabeth Porter 《政治学》1998,18(1):25-32
Increasing the political representation of women in Northern Ireland is part of fostering political pluralism. First, the political representation of women requires democratic participation and a justification of 'women' as a category. Second, specific factors of culture and the church unique to Ireland hinder women's participation in elected politics, and there are additional factors of class, violence, and nationalism that are peculiar to Northern Ireland. Third, gender quotas are successful elsewhere, but alone will not alter the powerful resistance to feminist change in Northern Ireland. Structures to encourage inclusionary politics must create spaces for political women to be transformative agents. 相似文献
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Elisabeth Jay 《Women's history review》2016,25(1):74-88
Viewing Constance Maynard's unwieldy life-writings within the tradition of spiritual autobiography reveals many of the irresolvable tensions with which she wrestled. Although she chose to see her public role as spearheading a crusade against modern rationalism, her inner life was as much concerned with the struggle to repudiate her parents’ ascetic Evangelical piety in favour of a more emotionally intense spirituality. Her conviction of conversion's centrality fostered a sense of mission which bolstered a sense of her own exceptionality as a ‘prophet’ chosen by God. This in turn nourished her belief that she was justified in exempting herself from the roles and relationships conventionally assigned to her gender, by pursuing same-sex desire and sexless motherhood. 相似文献
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Data from Swedish court judgments of all 124 women convicted of homicide during 20 years was analyzed. The typical pattern was an abused woman who kills her intimate partner at home with a knife, often with alcohol involved. A subsample (n = 66) was analyzed qualitatively, with a focus on intimate partner relationships. The findings indicate that female homicides usually take place after a long progression of violence and reflect women’s subordinate gendered position. Situational triggers finally lead up to the killing event. Gender equality and the so-called woman-friendly welfare state in Sweden do not appear to reduce women’s volatility in violent relationships. 相似文献