Incidental findings in CT colonography: literature review and survey of current research practice

Incidental findings (IFs) of potential medical significance are seen in approximately 5-8 percent of asymptomatic subjects and 16 percent of symptomatic subjects participating in large computed tomography (CT) colonography (CTC) studies, with the incidence varying further by CT acquisition technique. While most CTC research programs have a well-defined plan to detect and disclose IFs, such plans are largely communicated only verbally. Written consent documents should also inform subjects of how IFs of potential medical significance will be detected and reported in CTC research studies.     

Validation of Real‐time PCR Assays for Bioforensic Detection of Model Plant Pathogens

The U.S. agricultural sector is vulnerable to intentionally introduced microbial threats because of its wide and open distribution and economic importance. To investigate such events, forensically valid assays for plant pathogen detection are needed. In this work, real‐time PCR assays were developed for three model plant pathogens: Pseudomonas syringae pathovar tomato, Xylella fastidiosa, and Wheat streak mosaic virus. Validation included determination of the linearity and range, limit of detection, sensitivity, specificity, and exclusivity of each assay. Additionally, positive control plasmids, distinguishable from native signature by restriction enzyme digestion, were developed to support forensic application of the assays. Each assay displayed linear amplification of target nucleic acid, detected 100 fg or less of target nucleic acid, and was specific to its target pathogen. Results obtained with these model pathogens provide the framework for development and validation of similar assays for other plant pathogens of high consequence.     

Understanding the Authoritative Parenting–Early Adolescent Tobacco Use Link: The Mediating Role of Peer Tobacco Use

Eighth-grade students (N = 156) completed questionnaires in which they reported on their perceptions of parents' warmth, structure, and psychological autonomy granting (used to create an index of authoritative parenting) and their own levels of tobacco use. Adolescents were also asked to list the names of other students at their school with whom they spent time (friends). Independent reports obtained from these friends were used to form an index of the mean level of tobacco use among each adolescent's friends. Higher levels of authoritative parenting were associated with lower levels of tobacco use among target adolescents. The association between parental authoritativeness and adolescent tobacco use was mediated by levels of tobacco use among peers. An amplification effect was observed in which adolescents were particularly unlikely to use tobacco products when they both received authoritative parenting at home and were members of non-tobacco-using peer groups.     

THE POLITICS OF ROAD FUNDING: REMOTE ABORIGINAL COMMUNITIES AND FEDERALISM IN WESTERN AUSTRALIA

Abstract: This paper illustrates how remote Aboriginal communities shape rural road classification and funding policies in three Western Australian shires. The Australian federal system is characterised by a complex range of commonwealth and state governmental agencies competing for political space within different localities. Because Aborigines are constituents of the commonwealth and the state, a distinction is drawn between local government political activity, and politics that occur within the locality of a shire.
Success in influencing policy-making processes throughout the federal system stems from the participants' ability to exploit the system. The Aboriginal impact on road policy-making within remote localities is linked to electoral, bureaucratic, and sectional interest politics. These are features of governing and they provide a conceptual framework for the organisation of political activity by commonwealth, state, and local agencies, and Aboriginal communities.     

Spillover effects of inclusion of classmates with emotional problems on test scores in early elementary school

Over the last decade, the federal government has directed schools to provide educational instruction for students with special needs in general education settings to the extent possible. While there is mixed evidence on the effects of these inclusion policies on the students with special needs, research examining potential spillovers of inclusion on non‐disabled classmates has been scarce. There is particularly little research on the effects of inclusion policies on classmates during early elementary grades. This paper begins to fill in this gap by using a nationally representative, longitudinal survey of kindergartners. Cross‐sectional results suggest that having a classmate with an emotional problem decreases reading and math scores at the end of kindergarten and first grade by over 10 percent of a standard deviation, which is one‐third to one‐half of the minority test score gap. To control for nonrandom sorting of students to schools, as well as students to classrooms, this paper uses school‐level and then student‐level fixed effects. Results from the preferred empirical models suggest a decrease of approximately 5 percent of a standard deviation in math and reading scores, though the reading results are less robust. The results also indicate moderate racial and gender differences in the effects. © 2010 by the Association for Public Policy Analysis and Management.