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A case of fatal myocarditis in a 24-year-old otherwise healthy man is described. It was possible to cultivate Salmonella typhimurium from the alimentary tract, the blood, the liver and skeletal muscles. The possibility of a solitary myocarditis with fatal outcome due to Salmonella typhimurium infection is discussed. Such a case seems not to have been mentioned previously in the literature.The problems concerning the statistical registration of such a death are briefly discussed. 相似文献
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Jens Peter Frølund Thomsen 《Scandinavian political studies》2012,35(2):159-178
As European majority members are often hostile toward ethnic minorities, it is important to identify sources that reduce opposition to immigrants. First, focusing on Denmark, this article examines whether intergroup contact influences attitudes toward ethnic minority rights (henceforth: ‘ethnic tolerance’). Second, this study tests whether the contact‐tolerance relationship is mediated by self‐disclosure and symbolic threat. Furthermore, contact is measured as workplace contact in order to reduce self‐selection biases. The empirical tests are performed on a Danish high‐quality national probability sample from 2009 (N = 1,929). Analysis shows that intergroup contact generates ethnic tolerance because workplace contact weakens threat perceptions and stimulates disclosure of personal information. Generally, these results suggest that regular intergroup contact can improve ethnic relations in contemporary democracies. 相似文献
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Kingbäck M Karlsson L Zackrisson AL Carlsson B Josefsson M Bengtsson F Ahlner J Kugelberg FC 《Forensic science international》2012,214(1-3):124-134
Venlafaxine (VEN) is an antidepressant drug mainly metabolized by the cytochrome P450 (CYP) enzyme CYP2D6 to the active metabolite O-desmethylvenlafaxine (ODV). VEN is also metabolized to N-desmetylvenlafaxine (NDV) via CYP3A4. ODV and NDV are further metabolized to N,O-didesmethylvenlafaxine (DDV). VEN is a racemic mixture of the S- and R-enantiomers and these have in vitro displayed different degrees of serotonin and noradrenaline reuptake inhibition. The aim of the study was to investigate if an enantioselective analysis of VEN and its metabolites, in combination with genotyping for CYP2D6, could assist in the interpretation of forensic toxicological results in cases with different causes of deaths. Concentrations of the enantiomers of VEN and metabolites were determined in femoral blood obtained from 56 autopsy cases with different causes of death. The drug analysis was done by liquid chromatography tandem mass spectrometry (LC/MS/MS) and the CYP2D6 genotyping by PCR and pyrosequencing. The mean (median) enantiomeric S/R ratios of VEN, ODV, NDV and DDV were 0.99 (0.91), 2.17 (0.93), 0.92 (0.86) and 1.08 (1.03), respectively. However, a substantial variation in the relationship between the S- and R-enantiomers of VEN and metabolites was evident (S/R ratios ranging from 0.23 to 17.6). In six cases, a low S/R VEN ratio (mean 0.5) was associated with a high S/R ODV ratio (mean 11.9). Genotyping showed that these individuals carried two inactive CYP2D6 genes indicating a poor metabolizer phenotype. From these data we conclude that enantioselective analysis of VEN and ODV can predict if a person is a poor metabolizer genotype/phenotype for CYP2D6. Knowledge of the relationship between the S- and R-enantiomers of this antidepressant drug and its active metabolite is also important since the enantiomers display different pharmacodynamic profiles. 相似文献
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This article reports a study of the impact of marital status on interactional aspects of intimate partner violence (IPV) among
help-seeking women. Are there differences among marital status groups concerning (a) other sociodemographic variables, (b)
IPV categories, (c) interactional IPV variables, and (d) perception and interpretation of IPV? A representative sample of
157 women recruited from family counseling, the police, and shelters were interviewed. There was no significant sociodemographic
difference among the marital status groups. There were no significant differences pertaining to IPV categories, neither for
IPV severity, injury, duration, frequency, mortal danger, and regularity, nor for physical, psychological, or sexual IPV.
However, multivariate logistic regression showed that post-separation women were significantly more likely to have (a) had
longer duration since the last psychological and sexual IPV episode, (2) reported the physical IPV to be more predictable,
and (3) used more active coping strategies against physical IPV. However, our research was not able to determine if perception
and interpretation predict actual leaving behavior, or vice versa, or how the victim’s subjective perception and interpretation
of the IPV changes over time. 相似文献
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Choosing the number of seats in a legislature is a balancing act between efficiency and representativeness. This article focuses on representativeness and hypothesises that the larger the assembly, the higher the vote–seat proportionality, the higher the number of parties represented, and the higher the representation of otherwise under-represented groups. An approach using simulations of elections is introduced and applied in testing the hypotheses in the case of Danish local elections. Two thousand six hundred and forty-six elections are simulated, and a positive, but non-linear, relationship is demonstrated between number of seats and proportionality, number of parties, and percentage of women councillors. 相似文献