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排序方式: 共有198条查询结果,搜索用时 31 毫秒
81.
For highly degraded DNA samples of forensic casework, new miniSTR systems have been developed to supplement the current STR systems. In the present study, nine miniSTR loci were analyzed in 300 unrelated Koreans using three multiplex PCR systems (multiplex I: D10S1248, D14S1434 and D22S1045; multiplex II: D1S1677, D2S441 and D4S2364; and multiplex III: D3S3053, D6S474 and D20S482), and allele frequencies and forensic parameters were calculated. These data demonstrated that D10S1248, D2S441, D22S1045, D14S1434, and D6S474 are as highly informative as the CODIS STRs suggesting that the miniSTRs could be useful for forensic analysis of degraded DNA.  相似文献   
82.
In this paper I investigate how legislators behave in extremely pork-oriented, or pork-dominant, systems where virtually no party-line voting takes place and politicians strive to deliver individual/local benefits instead of national public policies. I argue that, in the pork-dominant context, most legislators vote with the president, who controls access to the pork pipeline, irrespective of their party affiliations. Thus, the president’s party legislators should have little incentive to vote against the president, regardless of voter demands for pork or policy; however, sometimes opposition-party legislators elected particularly from more-developed districts (where voters often desire policy over pork) should have strong incentives to vote against the president. These arguments are supported with quantitative studies of the post-authoritarian Philippine House of Representatives. It is found that, in the highly homogeneous legislature dominated by pork-seeking politicians, (1) most bills are passed with unanimous or near-unanimous consent, (2) governing-party legislators almost always vote with the majority of the members of the parliament, regardless of voters’ socio-economic conditions, and (3) opposition-party legislators, especially in more-developed areas, tend to vote against the parliamentary majority. These findings indicate that voters’ high socio-economic status promotes programmatic accountability, leading their representatives to undermine voting unity within the extremely cohesive pork-dominant legislature.  相似文献   
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Findings of a 3- to 4-year prospective investigation of personality, temperament, and behavioral factors predictive of the later development of disordered eating in an adolescent population are presented. The sample consisted of 726 girls and 698 boys who entered the study in grades 7–10 in year 1 or in grade 7 in year 2. Predictors of eating disorder risk score were determined separately by gender. For both girls and boys, the latent variable of negative affect/attitudes determined at study entrance was the only significant predictor of final-year risk score. Semistructured diagnostic interviews confirmed an eating disorder diagnosis in 52.8% of 36 female subjects in the high eating disorder symptom group. A substantial history of lifetime and current comorbidity also was noted in this group. The function of negative affect/attitudes as a generalized psychopathology vulnerability factor and as a specific factor increasing risk for disordered eating is discussed.  相似文献   
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A number of DNA marker types suitable for human identification and parentage testing have been developed, of which single nucleotide polymorphisms (SNPs) merit attention as they are abundant, genetically stable, and amenable to high-throughput automated analysis. In this regard, 24 highly informative SNP markers representing each 22 autosome and both sex chromosomes were selected, and the allele and genotype frequencies of these SNPs were determined in a group composed of 30 unrelated Koreans. Based on frequency data from this group, the estimated probability of identity (P(I)) and probability of paternity exclusion (P(E)) with 22 autosomal SNP loci were 1.905x10(-10) and 98.9%, respectively. The SNPs in this study offer a small but highly accurate database that will be an essential reference for SNP-based forensic application in the future.  相似文献   
88.
Forensic mitochondrial DNA analysis of 691 casework hairs   总被引:1,自引:0,他引:1  
A five year retrospective review of mitochondrial DNA (mtDNA) analysis on 691 casework hairs was carried out. A full or partial mtDNA profile was obtained for > 92% of hairs. With increasing age of the hair, the likelihood of obtaining a full profile decreased, although "mini-primer sets" could often be used to capture a partial profile. With increasing color and diameter of the hair, the likelihood of obtaining a profile increased. Full or partial profiles were obtained on more than 80% of 114 hairs < or = 1.0 cm. Mixtures were observed in 8.7% of hairs tested; mixtures increased with the age of the hair and were presumed to be due to exterior surface contamination that could not be sufficiently cleaned prior to extraction, since the overall level of laboratory contamination was low. The frequency of sequence heteroplasmy was 11.4%, and both hot-spot and novel sites were observed. In about one-third of these observations, another sample in the case showed either the same heteroplasmic site or a nucleotide substitution at that site.  相似文献   
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This paper attempts to contrast the industrial policymaking “styles” of the U.S. and Sweden. The study looks past the clutter of economic and trade issues into underlying political culture and institutional regime. The conceptual framework of pluralism versus managed pluralism is employed to examine some complex issues related to economic and industrial management, and to help explain the problem. A strategy to advance the long-term interests of a country must go beyond the “legislative pork barrel” approach, simply to create employment and to keep jobs. Industrial policy must have both institutional and policy linkages. Government-business cooperation at a sectoral level is essential in providing policy loans and tax incentives. The state, to facilitate policy implementation, has to pursue linkage developments between industrial, human resource, economic, and trade policies.  相似文献   
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