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51.
Lindberg L Brauer S Wollmer P Goldberg L Jones AW Olsson SG 《Forensic science international》2007,168(2-3):200-207
A new breath alcohol (ethanol) analyzer has been developed, which allows free exhalation, standardizes measured exhaled alcohol concentration to fully saturated water vapor at a body temperature of 37 degrees C (43.95 mg/L) and includes a built-in self-calibration system. We evaluated the performance of this instrument by comparing standardized alcohol concentration in freely expired breath (BrAC) with arterial (ABAC) and venous (VBAC) blood alcohol concentrations in fifteen healthy volunteers who drank 0.6 g of alcohol per kg body weight. The precision (coefficient of variation, CV) of the analyzer based on in vivo duplicate measurements in all phases of the alcohol metabolism was 1.7%. The ABAC/BrAC ratio was 2251+/-46 (mean+/-S.D.) in the post-absorptive phase and the mean bias between ABAC and BrAC x 2251 was 0.0035 g/L with 95% limits of agreement of 0.033 and -0.026. The ABAC and BrAC x 2251 were highly correlated (r=0.998, p<0.001) and the regression relationship was ABAC = 0.00045 + 1.0069 x (BrAC x 2251) indicating excellent agreement and no fixed or proportional bias. In the absorption phase, ABAC exceeded BrAC x 2251 by at most 0.04+/-0.03 g/L when tests were made at 10 min post-dosing (p<0.05). The VBAC/BrAC ratio never stabilized and varied continuously between 1834 and 3259. There was a proportional bias between VBAC and BrAC x 2251 (ABAC) in the post-absorptive phase (p<0.001). The pharmacokinetic analysis of the elimination rates of alcohol and times to zero BAC confirmed that BrAC x 2251 and ABAC agreed very well with each other, but not with VBAC (p<0.001). We conclude that this new breath analyzer using free exhalation has a high precision for in vivo testing. The BrAC reflects very accurately ABAC in the post-absorption phase and substantially well in the absorption phase and thereby reflects the concentration of alcohol reaching the brain. Our findings highlight the magnitude of arterio-venous differences in alcohol concentration and support the use of breath alcohol analyzers as a stand-alone test for medical and legal purposes. 相似文献
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While faculty members in universities are inventing and their universities are aggressively marketing the associated intellectual property, many universities have not been pleased with the financial results. Is it due to inadequacy of effort by the universities, or due to objective obstacles? This short article provides insights into some of the real and perceived challenges facing the Technology Transfer Offices of university, and brings relevant observations to the discussion. 相似文献
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Katherine A. Kuvalanka Camellia Bellis Abbie E. Goldberg Jenifer K. McGuire 《Family Court Review》2019,57(1):54-71
Family courts have lacked familiarity with evidence‐based recommendations regarding the best interests of transgender and gender‐nonconforming (TGNC) children, resulting in some affirming parents losing physical and/or legal custody. This exploratory, qualitative study with 10 affirming mothers of TGNC children who had experienced custody‐related challenges reported on salient themes, including “blame” for causing children's gender nonconformity, coercion by ex‐partners, bias in the courts, negative impact on children, emotional and financial toll on participants, and the critical importance of adequate resources. Findings indicate the need for better‐educated family court professionals, as well as socioemotional support and financial and legal assistance for affirming parents of TGNC children. 相似文献
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Megan Stubbs-Richardson H. Colleen Sinclair Rebecca M. Goldberg Chelsea N. Ellithorpe Suzanne C. Amadi 《American Journal of Criminal Justice》2018,43(1):39-66
The present study examines gender differences in bullying in high school. Unique contributions include comparisons of both victimization and perpetration rates across four subtypes of bullying: physical, verbal, relational, and cyber. Further, as we conceptualize bullying within the larger framework of literature on social rejection, we also address whether there are gender differences in experiencing social rejection–in the form of bullying–and responding with aggression, as opposed to asocial or prosocial behavior. The literature yields mixed findings across these three questions (i.e., gender differences in experiences with victimization and perpetration and responses to those experiences), suggesting sample variations (Archer Review of General Psychology, 8(4), 291–322, 2004; Archer & Coyne Personality and Social Psychology Review, 9, 212–230, 2005; Card, Stucky, Sawalani, & Little Child Development, 79, 1185–1229, 2008). Thus, we explored experiential differences in our sample, and hypothesized based on the tend and befriend model (Taylor et al., 2000) that girls would be more likely than boys to respond to bullying with prosocial behaviors. With regard to victimization and perpetration differences, we found that male students both experienced and perpetrated significantly more physical bullying. Boys were also significantly more likely to report experiencing verbal bullying than girls. No significant differences emerged for relational or cyber bullying. With regard to responses, social withdrawal was more common than aggressive responding, but consistent with the tend and befriend model, girls chose prosocial responses significantly more than boys, whereas boys were just as likely to choose antisocial responding as prosocial responding. These results suggest that gender should be considered in studies addressing the question of when experiences with rejection–in its many forms–results in antisocial versus prosocial behavior. 相似文献
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Pascal Sciarini Fabio Cappelletti Andreas C. Goldberg Simon Lanz 《Swiss Political Science Review》2016,22(1):75-94
While electoral research usually distinguishes voters from abstainers, in the Swiss direct democratic context one needs to take into account a third category of citizens, the selective voters, who decide anew at each vote whether they will participate or not. This article offers an investigation of this common but under‐researched form of participation. To that end, we take advantage of a unique data‐set linking official turnout data with survey data. Our results show that selective voters constitute the bulk of the electorate. While they form a heterogeneous group in terms of socio‐demographic characteristics, selective voters lean more towards abstainers than towards permanent voters with respect to political variables. We argue that this is not necessarily bad news in terms of democratic theory. 相似文献
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Andreas C. Goldberg 《Swiss Political Science Review》2014,20(2):305-329
The traditional cleavages like social class or religion are often reported to have lost explanatory power for the voting decision. Regarding the religious cleavage, the evidence is ambiguous depending on the choice of cases and indicators used. The present study tests the impact of religion for the preference to vote the Christian Democratic Party of Switzerland (CVP) using data from the 2007 and 2011 Swiss national elections. Additional to the inclusion of individual variables, a special focus lies on contextual effects. The estimated hierarchical linear models confirm a prevailing influence of the simple individual factors and the presence of a significant contextual effect. Statistical evidence is also presented for some of the supposed interaction effects between individual and contextual religious variables. 相似文献