共产党员理想信念建设机制创新探赜

<正>共产党员理想信念的确立、教育不是一劳永逸的。理想信念与社会生活之间有着紧密的联系并始终处于互动之中。社会历史条件的变化,总是不断把新的问题、新的矛盾提到理想信念教育面前。如果从精神文化发展的大视域去研究理想信念建设的理论和实践,需要进一步从现实人的发展、人的需求以及人在实践中的主体地位的角度探索构建共产党员理想信念建设的新机制问题。我们这里说的"理想信念建设的机制",指的是带观律性的理想信念建设模式。     

Development of a specific fragment pattern-based quadrupole-Orbitrap mass spectrometry method to screen adulterated products of phosphodiesterase-5 inhibitors and their analogues

Recently, adulterated supplements with phosphodiesterase-5 inhibitors (PDE-5i) have frequently observed. New synthetic analogues obtained from the chemical modification of parent compounds are frequently found in illicit products despite continuous efforts to inspect for these adulterants. A rapid and accurate method based on quadrupole-Orbitrap mass spectrometry was developed for simultaneously confirming and quantifying 85 PDE-5i and derived analogues present in illicit products for erectile dysfunction (ED). Common ions of PDE-5i according to their similar structures were proposed based on MS/MS fragmentations. These common ions could be an important diagnosis of their presence targets or new emerging analogues in supplements. Several validation parameters were employed, resulting in a limit of detection and quantification of 0.09–8.55 ng/mL and 0.24–17.10 ng/mL, respectively. The linear correlation coefficient (r²) was higher than 0.995, and mean recoveries of target compounds were in the range of 82–118%. A total of 187 illicit products, obtained from on/offline markets over a period of 3 years (2015–2017), were screened by the established method. Approximately 53% of them were adulterated with PDE-5i or derived analogues at concentrations of 0.1–726.0 mg/g in the illicit products. In the interests of public health, this study describes a rapid and accurate method to determine PDE-5i and new emerging analogues in adulterated products.     

Same Routines,Different Effects: Gender,Leisure, and Young Offending

The current study seeks to extend routine activity theory by examining how gender conditions the relationship between leisure activities and adolescent delinquency. Using OLS regression with a sample of high school students from Toronto (n = 2,209), we find that (1) engaging in more unstructured and unsupervised activities with peers is associated with delinquency more strongly for boys than for girls, but is associated with substance use equally across gender; (2) this pattern is likely due to gender differences in the locations or contexts of leisure activities; and (3) prosocial leisure activities are associated with less delinquency only for boys. In general, routine activity theory appears apt at explaining the substance use of boys and girls, but is less capable of explaining the property and violent offending of girls. We discuss our findings and their implications for the growing body of research extending routine activity theory to explain gender differences in delinquency.     

Identifying core topics in technology and innovation management studies: a topic model approach

The study of technology and innovation management (TIM) has continued to evolve and expand with great speed over the last three decades. This research aims to identify core topics in TIM studies and explore their dynamic changes. The conventional approach, based on discrete assignments by subjective judgment with predetermined categories, cannot effectively capture latent topics from large volumes of scholarly data. Hence, this study adopts the topic model approach, which automatically discovers topics that pervade a large and unstructured collection of documents, to uncover research topics in TIM research. The 50 topics of TIM research are identified through the Latent Dirichlet Allocation model from 11,693 articles published from 1997 to 2016 in 11 TIM journals, and top 10 most popular topics in TIM research are briefly reviewed. We then explore topic trends by examining the changes in topics rankings over different time periods and identifying hot and cold topics of TIM research over the last two decades. For each of the 11 TIM journals, the areas of subspecialty and the effects of editor changes on topic portfolios are also investigated. The findings of this study are expected to provide implications for researchers, journal editors, and policy makers in the field of TIM.     

The impact of an intensive inpatient violent offender treatment programme on intermediary treatment targets,violence risk and aggressive behaviour in a sample of mentally disordered offenders*

This study examined the impact of an intensive inpatient violent offender treatment programme, Life Minus Violence-Enhanced (LMV-E), on intermediary treatment targets, risk for violence, and aggressive behaviour during treatment in a sample of male mentally disordered offenders. Using quasi-experimental design, offenders who completed LMV-E and a comparison group showed reduced problems with impulsivity and anger regulation and improvements in social problem solving. Aggregate risk for future violence lessened in both treatment and comparison groups, although by a significantly greater degree for the comparison group. The aggressive behaviour of both groups reduced. Completion of the LMV-E conferred additional improvements in some facets of social problem solving and anger regulation. Neither group showed improvements in empathic responses, coping skills or problematic interpersonal style. Overall, these results suggest anger regulation, impulsivity and social problem solving are most amenable to change, that reductions in certain facets of these dynamic risk factors transpires with nonspecific psychiatric inpatient treatment, but that the LMV-E, a cognitive behavioural violence specific psychological treatment, confers greater change in some facets of social problem solving and anger regulation.     

Quasi-experimental designs for community-level public health violence reduction interventions: a case study in the challenges of selecting the counterfactual

Objectives

We highlight the importance of documenting the step-by-step processes used for the selection of comparison areas when evaluating a community-level intervention that targets a large-scale community.

Methods

We demonstrate the proposed method using a propensity score matching framework for an impact analysis of the Cure Violence Public Health Model in Philadelphia. To select comparison communities, propensity score models are run using different levels of aggregation to define the intervention site. We discuss the trade-offs made.

Results

We find wide variation in documentation and explanation in the extant literature of the methods used to select comparison communities. The size of the unit of analysis at which a community is measured complicates the decision processes, and in turn, can affect the validity of the counterfactual.

Conclusions

It is important to carefully consider the unit of analysis for measurement of comparison communities. Assessing the geographic clustering of matched communities to mirror that of the treated community holds conceptual appeal and represents a strategy to consider when evaluating community-level interventions taking place at a large scale. Regardless of the final decisions made in the selection of the counterfactual, the field could benefit from more systematic diagnostic tools that document and guide the steps and decisions along the way, and ask: “could there have been another way of doing each step, and what difference would this have made?” Overall, across community-level evaluations that utilize quasi-experimental designs, documentation of the counterfactual selection process will provide a more fine-grained understanding of causal inference.

     

关于工资集体协商机制有关问题的思考

推动“工资共决”,建立集体协商机制已经成为目前中国实现职工工资正常增长的主要途径和重要制度保障,并上升到了国家战略的高度.工资集体协商面临历史的发展机遇.但是,由于在实践这一制度的过程中,认识、主体、配套制度等方面存在的不足,产生一些“瓶颈”问题,如果不结合我国国情认真加以研究解决,将会影响全面推动建立工资集体协商机制...     

How does technology-based monitoring affect street-level bureaucrats' behavior? An analysis of body-worn cameras and police actions

Body-worn cameras may produce varying effects on police behavior, depending on the agency-specific accountability context in which the technology adoption is embedded. The cameras may encourage coercive police actions when acquired to incentivize performance, such as by protecting officers from false complaints. By contrast, when acquired to enhance procedural accountability, such as by enabling closer scrutiny of officer misconduct, the cameras may discourage coercive police actions. Based on this framework, this study examined the case of the New Orleans Police Department, an agency that implemented a body-worn camera program to enhance both performance and procedural accountability. Results of Bayesian structural time-series modeling with synthetic control show that the program increased the number of investigatory stops and follow-up measures (i.e., frisk, search, citation, arrest) while decreasing the ratio of more-to-less coercive measures during stops (i.e., arrest/citation-to-warning ratio and search-to-frisk ratio). However, the program had a null effect on the minority-to-White suspect ratio, despite the agency's bias-free policing initiative. The percentage of frisks and searches detecting drugs or weapons also declined. A broader implication of the findings is that technology-based monitoring mechanisms are important, but not a silver bullet for improving the behavior of street-level bureaucrats.     

复方银杏丹参颗粒对H9c2细胞氧化应激损伤的保护作用

目的 观察复方银杏丹参颗粒(Compound Yinxing Danshen Granules,CYDG)对大鼠心肌细胞氧化应激损伤的保护作用.方法 利用过氧化氢(hydrogen peroxide,H2O2)作为外源性自由基生成系统,体内模拟心肌细胞的脂质过氧化损伤,观察CYDG对H2O2致心肌细胞损伤的保护作用.结...     

Business model–dynamic capabilities and open innovation initiatives in research-intensive organisations: A case of Australia's national science agency

Publicly funded national science agencies create value as innovation catalysts and through their scientific and research missions, they tackle wicked problems. Understanding how dynamic capabilities and business model innovation enable research-intensive organisations to seize the market in the mission is key to translating bold new science that has impact. We qualitatively explore how Australia's national science agency—the Commonwealth Scientific Industrial Research Organisation (CSIRO)—has pursued open innovation to support business model–dynamic capabilities in an evolving publicly funded landscape. We reflect on the value of open innovation initiatives that have allowed the CSIRO to ambidextrously pursue world-class science while achieving impact.

Points for practitioners

• Dynamic capabilities and business model innovation are strategic tools for publicly funded national science agencies seeking to seize the market in the mission.
• We examine a case of business model–dynamic capabilities in CSIRO.
• Open innovation has been important for CSIRO as part of an ambidextrous approach.