Evaluation of the role of abstinence in heroin overdose deaths using segmental hair analysis

In the body heroin is rapidly metabolized to 6-acetylmorphine and morphine. Victims of lethal heroin overdose often present with fairly low blood concentrations of morphine. Reduced tolerance due to abstinence has been proposed to account for this finding. The aim of the present study was to examine the role of abstinence in drug-related deaths by comparing recent and past exposure to opioids using segmental hair analysis with the postmortem blood morphine concentrations in deceased heroin users. The study included 60 deceased drug addicts in the Stockholm area, Sweden. In 32 cases, death was not related to heroin intake. In 18 of the 28 heroin fatalities, opioids were absent in the most recent hair segment, suggesting a reduced tolerance to opioids. However, the blood morphine levels were similar to those found in the 10 subjects that showed continuous opioid use. Hair and blood analysis disclosed an extensive use of additional drugs that directly or indirectly may influence the opioid system. The results suggest that abstinence is not a critical factor for heroin overdose death. Obviously tolerant subjects die after intake of similar doses. Other factors, particularly polydrug use, seem to be more causally important for these deaths.     

Standardized assessment of substance-related, other psychiatric, and comorbid disorders among probationers

This study examined the prevalence of alcohol- and substance-related disorders in a random sample of 627 adult probationers in Illinois. The investigation also explored the prevalence of major psychiatric disorders and their co-occurrences with alcohol and substance use disorders. To detect the presence of psychiatric disorders, researchers employed standardized assessment tools based on Diagnostic and Statistical Manual of Mental Disorders criteria. Overall, results showed that probationers had significantly higher rates of psychiatric disorders, substance use disorders, and co-occurring disorders compared with persons in the general population. In light of these findings, probation administrators are urged to invest more resources in treating drug use, mental illness, and codisorders, the latter of which is associated with a higher risk of violent behaviors.     

Meckel's diverticulum and intestinal obstruction--report of a fatal case

Meckel's diverticulum is an uncommon cause of intestinal obstruction in adult life. Rarely Meckel's diverticulum is complicated by a mesodiverticular band, which is believed to be a remnant of a vitelline artery. When this abnormality occurs it is associated with high mortality. We present a case of a 48-year-old man with increasing abdominal pain and vomiting for 3 days. Meckel's diverticulum was not taken into diagnostic consideration, and the man died. Autopsy revealed a Meckel's diverticulum with a mesodiverticular band and intestinal obstruction. Histological examination of cross sections of the mesodiverticular band showed the presence of an artery. Because of the high mortality of this rare anatomic anomaly in adults, we find the case of interest.     

Cross-sectoral strategies in global sustainability governance: towards a nexus approach

The recent shift from the Millennium Development Goals to the much broader Sustainable Development Goals has given further impetus to the debate on the nexus between the multiple sectors of policy-making that the Goals are to cover. The key message in this debate is that different domains—for instance, water, energy and food—are interconnected and can thus not be effectively resolved unless they are addressed as being fully interrelated and interdependent. Yet while this overall narrative is forcefully supported in the new UN 2030 Agenda for Sustainable Development and the 17 Sustainable Development Goals that are the main part of this agenda, many Goals still remain sectoral in their basic outlook. This now requires, we argue, a new focus in both policy and research on the nexus between different Sustainable Development Goals, especially with a view to reforms in the overall institutional setting that is required to sufficiently support such a nexus approach. This article thus examines the nexus approach in the context of the Sustainable Development Goals and identifies multiple avenues for its institutionalisation in global governance.     

Dental age in Central Poland

Precise evaluation of the developmental stage of a child is an integral part of both diagnosis and treatment of pediatric patients; it is also essential in forensic medicine and dentistry. Among radiological methods for dental age estimation in children the Demirjian's method is widely used, however original standards elaborated for the French-Canadian population are mostly not suitable for other populations. The aim of the study was to compare the dental age of children from the region of Mazovia (Central Poland) with the developmental standards presented by Demirjian, to analyse sexual dimorphism of dental age in the studied group and to estimate validity of the Demirjian's standards for the studied Polish population. The material consisted of clinical files and panoramic X-ray images of 994 children aged from 6 to 16 in good general health, without development impairments. Chronological ages of the patients were established. Next dental ages were estimated by means of the Demirjian method based on developmental maturity of seven left mandibular permanent teeth. It was found that the standards were significantly different from the chronological ages in the studied population, which means that dental development was considerably accelerated. The most significant acceleration was observed in girls aged 11 and 12, as well as in 13-year-old boys; in both groups a considerable acceleration of the dental age was seen in 6-year-olds. No statistically significant differences between dental ages of girls and boys were observed in particular age groups. There were devised gender-specific equations allowing for adaptation of original Demirjian's scores for estimation of dental age in the population of Mazovia (Central Poland). In conclusion, the developmental standards used by Demirjian are not suitable in the case of the population of children of Central Poland. Therefore, it is necessary to establish new tables for this population.     

The Sustainable Development Goals and REDD+: assessing institutional interactions and the pursuit of synergies

This paper analyzes potential synergies between two recent sustainable development initiatives, namely the Sustainable Development Goals (SDGs) and reducing emissions from deforestation and forest degradation (REDD+), a climate mitigation mechanism negotiated under the auspices of the United Nations Framework Convention on Climate Change. The paper elaborates a conceptual framework based on institutional interactions and distinguishes core, complementary, and supplementary synergies that may be realized between the SDGs and REDD+. Potential synergies are analyzed at the global level, as well as within two national-level contexts: Indonesia, with its long-standing REDD+ programme, and Myanmar, which is in the early stages of implementing REDD+. Both are now also engaging nationally with the SDG implementation process. Our research draws on literature review and document analysis, direct observations of global policy processes relating to REDD+ and SDGs, as well as extensive engagement (of one author) at national level in Indonesia and Myanmar. Our analysis reveals that there are currently significant opportunities to pursue synergies in the implementation of these international initiatives at the national level, although pro-active interaction management is necessary, especially to achieve complementary synergies.     

The Estonian way of deinstitutionalisation. Experiences from an ethnographic research in SOS Children’s Village

This study provides insight into change processes of child residential care as depicted by ethnographic research on Estonian SOS Children’s Villages (SOS CV). Through the analysis of daily life in substitute homes, this study aimed to gain an in-depth and contextualised understanding of this deinstitutionalisation process. The changing approach of SOS CVs from institutional village-life-based to community-based approaches where nonbiological children are raised is discussed. The interpretation of said changes as deinstitutionalisation and their complicated nature is outlined. The latter is attributed to the divergent effects of activities. The findings ultimately lead to the conclusion that such change processes result in both challenges and difficulties to the Estonian substitute care system.     

The Influence of Preburial Insect Access on the Decomposition Rate

Abstract: This study compared total body score (TBS) in buried remains (35 cm depth) with and without insect access prior to burial. Sixty rabbit carcasses were exhumed at 50 accumulated degree day (ADD) intervals. Weight loss, TBS, intra‐abdominal decomposition, carcass/soil interface temperature, and below‐carcass soil pH were recorded and analyzed. Results showed significant differences (p << 0.001) in decomposition rates between carcasses with and without insect access prior to burial. An approximately 30% enhanced decomposition rate with insects was observed. TBS was the most valid tool in postmortem interval (PMI) estimation. All other variables showed only weak relationships to decomposition stages, adding little value to PMI estimation. Although progress in estimating the PMI for surface remains has been made, no previous studies have accomplished this for buried remains. This study builds a framework to which further comparable studies can contribute, to produce predictive models for PMI estimation in buried human remains.     

A Closer Look at an Eye for an Eye: Laypersons’ Punishment Decisions Are Primarily Driven by Retributive Motives

According to recent research on laypersons’ punitive attitudes people’s sentencing decisions are primarily driven by a desire for retribution. The research designed to test this notion, however, can be criticized for suffering from several limitations. Three online-based studies were conducted with samples from Western Europe with the aim of replicating the findings of Carlsmith (J Exp Soc Psychol 42:437–451, 2006) in which participants’ punishment motives were inferred from their behavior in a process tracing task. In the present research, this approach was adopted and modified in order to provide a more conservative test for the notion that people mainly care about retribution. Although these modifications strongly influenced the overall pattern of results, retribution still was the most important punishment motive in all three studies.     

Partisan bias in inflation expectations

Public Choice - We examine partisan bias in inflation expectations. Our dataset includes inflation expectations of the New York Fed’s Survey of Consumer Expectations over the period June 2013...