A Three‐Locus,PCR‐based Method for Forensic Identification of Plant Material

Plant residue is currently an underutilized resource in forensic investigations despite the fact that many crime scenes, as well as suspects and victims, harbor plant‐derived residue that could be recovered and analyzed. Notwithstanding the considerable skill of forensic botanists, current methods of species determination could benefit from tools for DNA‐based species identification. However, DNA barcoding in plants has been hampered by sequence complications in the plant genome. Following a database search for usable barcodes, broad‐spectrum primers were designed and utilized to amplify and sequence the rbcL, trnL‐F, and rrn18 genetic loci from a variety of household plants. Once obtained, these DNA sequences were used to design species‐targeted primers that could successfully discriminate the source of plant residue from among the 21 species tested.     

Aromatic content in medium range distillate products--Part I: an examination of various liquids

Classification of ignitable liquids in accordance with voluntary consensus-based standards published by ASTM International has become increasingly specific, relying upon both the chemical composition and the boiling point range of submitted ignitable liquids. This classification system includes among others, specific classes for distillates and dearomatized distillates. In this study, a variety of medium-range ignitable liquids were analyzed by gas chromatography-mass spectrometry. Several methods of data analysis were utilized to examine the relative aliphatic and aromatic contents in these liquids. Results show that commercially available products in the medium range exhibit a broad range of compositions with respect to the relative proportion of aliphatic and aromatic compounds and that some liquids may not be easily classified. This study demonstrates the importance of examining the proportion of aliphatics:aromatics for classifying such liquids and suggests guidelines for differentiating medium range distillates, dearomatized distillates, and blended products.     

Anorectic sibutramine detected in a Chinese herbal drug for weight loss

In the presented case, a young healthy woman had ordered a Chinese herbal medicine, called "LiDa Dai Dai Hua Jiao Nang", via internet. She took this product for approximately 1 week, but on the second day she developed severe headache, vertigo and sensation of numbness. After discontinuing medication, symptoms disappeared within 2 days. For identification of the ingredients, a urine sample as well as a sample of the "LiDa" capsule were analysed by GC-MS and HPLC-DAD. One major ingredient was detected in urine as well as in the "LiDa" capsule and was identified as sibutramine. Quantification by HPLC-DAD yielded 27.4 mg sibutramine base, which is approximately two times the amount of the highest authorized single dose available on the pharmaceutical market in Germany. This case demonstrates a common problem with herbal medicines, where adulterations with synthetic therapeutic substances can lead to severe side effects and/or potentially fatal interactions with conventional medicines.     

Survival of severe amlodipine intoxication due to medical intensive care

We report the case of attempted suicide with amlodipine, chlorthalidone and mefenamic acid and subsequent medical intensive care measures which resulted in total recovery of a 42-year-old male. After admission to the medical intensive care unit the intoxicated patient was deeply hypotensive and needed fluid replacement, dobutamine and norepinephrine. Additionally insulin and calcium gluconate were given. Since hypotension persisted and the patient developed oliguria, terlipressin was applied and finally showed an effect on blood pressure and on urinary output. A volume overload of 7 L in the first 24 h resulted in a pulmonary edema. The patient was started on non-invasive ventilation with continuous positive airway pressure (CPAP) and frusemide was added to the therapy with good success. Quantitative determination of amlodipine in plasma samples was performed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The highest amlodipine concentrations was measured in the plasma sample collected approximately 8 h after ingestion of the drug, and was 393 microg/L. Four days later, it was possible to stop the treatment with catecholamines, at that time the amlodipine plasma concentration had declined to 132 microg/L, still tenfold higher than therapeutic (5-18 microg/L). Elimination half-life of amlodipine is approximately 55 h. After 6 days in the intensive care unit the patient was transferred to psychiatric treatment. Intensive care management and plasma levels in this intoxication case are compared to data from literature on other cases.     

Bedroom rape: sequences of sexual behavior in stranger assaults

This article examines the sequential, temporal, and interactional aspects of sexual assaults using sequential analysis. Fourteen statements taken from victims of bedroom-based assaults were analyzed to provide a comprehensive account of the behavioral patterns of individuals in sexually charged conflict situations. The cases were found to vary in the sexual severity of assault, distinguishing a variety of motivations and behavioral repertoires of offender and victim. Two quite distinct styles of offense were identified: multiple and single, which may have very different implications for research into rapist taxonomies and rape prevention strategies.     

Sixth Graders’ Conflict Resolution in Role Plays with a Peer,Parent, and Teacher

This study used conflict resolution role play vignettes and self-report surveys of 450 New York City 6th graders to examine associations between adolescents’ conflict resolution efficacy and social skills. Vignettes covered 3 social contexts, conflict with a peer (disagreement over activities), with a parent (raise in allowance), and with a teacher (low grade on report). Effective and ineffective strategies for resolving these conflicts were coded from the videotaped interactions. Adolescents were more often effective in resolving conflict with peers than with parents (χ²(1) = 7.10, p < .01). Strong communication skills cut across interpersonal context as associated with effective resolution. Assertiveness and absence of aggression were associated with effective conflict resolution in vignettes with peers. Assertiveness was also associated with effective conflict resolution in vignettes with parents, however nervousness was unexpectedly found to facilitate conflict resolution in vignettes with parents. Only skills observed within a particular context were associated with effective resolution in that context; self-report skills and cross-context observed skills were not associated with efficacy. Implications for implementation and evaluation of social skills curricula and conflict resolution process are discussed.An earlier version of this paper was presented at the meetings of the Society for Research on Adolescence, New Orleans, LA, April 2002Received Ph.D. in Developmental Psychology from Teachers College, Columbia University in 2004. Research interests include adolescent social competence and youth development programs.Received Ph.D. in Developmental Psychology from Pennsylvania State University in 1991. Research interests include the psychosocial correlates of puberty, stress reactivity, and health compromising behaviors and adjustment.Received Ph.D. in Developmental Psychology from Teachers College, Columbia University in 2002. Research interests include social competence, prevention research, and women’s health.Received Ph.D. in Developmental Psychology from Teachers College, Columbia University in 2002. Research interests include social competence, prevention research, and women’s health.Received Ph.D. in 1975 from University of Pennsylvania in Human Learning and Development. Research focus centers around designing and evaluating interventions aimed at enhancing the wellbeing of children living in poverty and associated conditions. Conducts research on transitional periods during childhood and adolescence, focusing on school, family and biological transitions in childhood, adolescence, and adulthood. Specific interests are in the factors that contribute to positive and negative outcomes, and changes inwell-being over these years.Received Ph.D. in Developmental Psychology from Columbia University in 1977. Research interests include tobacco, alcohol, and drug abuse prevention, violence prevention, AIDS risk reduction among adolescents, health promotion and disease prevention, smoking cessation.     

Why Voters Decide Late: A Simultaneous Test of Old and New Hypotheses at the 2005 and 2009 German Federal Elections

Against the background of a substantial rise of the number of late-deciding voters at recent elections the paper simultaneously tests four complementary hypotheses on the background of contemporary electors' timing of decision making. The traditional floating voter hypothesis fares best in this analysis: lacking partisan predispositions and a general detachment from politics appear as the main reasons why people take longer to make up their minds. Indifference and attitudinal ambivalence as well as mixed party-political signals from voters' social networks also lead to electors postponing their voting decisions. The hypothesis that late deciding is a consequence of increased availability and attention to mediated political information is refuted. Several long-term trends are discussed as reasons for the increase of late deciding.     

Power Resources of Parliamentary Executives: Policy Advice in the UK and Germany

This article compares the institutionalisation of policy advice inside offices which service chief executives in the UK and Germany. It focuses on the institutionalisation of ‘policy units’ during the early 1970s and late 1990s which reveals different patterns. Whereas British policy units are allowed to interfere in any departmental business and address a variety of issues, German policy units are narrowed to provide administrative support and avoid partisan issues. Applying a new institutionalist perspective and the veto approach, this article argues that institutionalisation processes as strategic interactions of organisational actors are affected by institutional features at the macro-level of parliamentary systems. These features include principles of cabinet decision-making and the electoral system with its effects on parliament and cabinet composition which both set veto positions in the executive and legislative decision arena. Next to these institutional features, the empirical evidence shows how organisational legacies account for the influential role of British policy units as power resource for the PM and the nearly irrelevance of German policy units as power resource for the Chancellor.