Validation studies of an immunochromatographic 1-step test for the forensic identification of human blood.

An immunochromatographic 1-step test for the detection of fecal occult blood was evaluated for applicability for the forensic identification of human blood in stained material. The following experiments were conducted: 1) determination of the sensitivity and specificity of the assay; 2) evaluation of different extraction media for bloodstains (sterile water, Tris buffer pH 7.5 provided in the test kit, 5% ammonia); 3) analysis of biological samples subjected to a variety of environmental insults; and 4) evaluation of casework samples. This immunochromatographic 1-step occult blood test is specific for human (primate) hemoglobin and is at least an order of magnitude more sensitive than previous methods for detecting human hemoglobin in bloodstains. The antigen is insensitive to a variety of environmental insults, except for exposure to certain detergents and household bleaches and prolonged exposure to certain preparations of luminol. The entire assay can be conducted in field testing conditions within minutes. When in the laboratory the supernatant from a DNA extraction is used for the assay, there is essentially no consumption of DNA for determining the presence of human hemoglobin in a forensic sample. The data demonstrate that this test is robust and suitable for forensic analyses.     

The tissue survival problem in using current methods of morphological study]

Time course of ultrastructural changes and RNA production in human brain and myocardial cells during the period between clinical and biological death is studied. Changes in the cytoplasm of brain neurons develop 4 hours after death, and 8 h post mortem the destructive changes in the cytoplasm and nuclei progress. During the period of 4-13 h post mortem the endotheliocyte nuclei are capable of producing RNA. Active production of RNA is on-going in the myocyte nuclei 4 h after death; the synthetic activity decreases by 8 h and by 13 h the synthetic activity in autopsy material is over.     

Evaluation of injuries features inflicted by shots from gas guns by emission spectral analysis

The authors describe a methodological approach to emission spectral analysis of material evidences aimed at evaluating the regularities of deposition of the shot metals at the site of injuries inflicted by gas guns. Injuries inflicted by gunshots with chemical cartridges and with shot cartridges, with and without obstructions, from different distances have been examined. The detected regularities may be useful in forensic medical expert evaluations by means of emission spectral analysis in cases with gas gunshots.     

The Israeli Patient's Rights Law: evidence for deprofessionalization?

In this paper, the Israeli Patient's Rights Law of 1996 is discussed within the framework of Haug's predicted process of deprofessionalization. It is argued that the law reflects global processes such as the diffusion of knowledge, consumerism, and values that emphasize human rights and democracy. By guaranteeing patients' access to medical information, by submitting medical decisions to extra-professional regulation, the law erodes professional power.     

Economic Outcomes and Voting Behaviour in a Multi-Party System: An Application to the Netherlands

This paper is an empirical study to the effects of economic outcomes on party choice for the Netherlands. In the first part of the paper we employ a multinomial logit model to examine the links between voters' characteristics and party choice. The results suggest that there are long-run movements in party choice which are unlikely be the result of changing economic outcomes. In the second part, we use time series analysis to determine the effects of economic conditions on short-run and medium-run movements in votes shares. The estimations results provide support for the responsibility hypothesis and for the predictions of the partisan voter model that left-wing (right-wing) parties benefit (suffer) from favourable economic growth prospects.