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We report the results of an inter-laboratory exercise on typing of autosomal single nucleotide polymorphisms (SNP) for forensic genetic investigations in crime cases. The European DNA Profiling Group (EDNAP), a working group under the International Society for Forensic Genetics (ISFG), organised the exercise. A total of 11 European and one US forensic genetic laboratories tested a subset of a 52 SNP-multiplex PCR kit developed by the SNPforID consortium. The 52 SNP-multiplex kit amplifies 52 DNA fragments with 52 autosomal SNP loci in one multiplex PCR. The 52 SNPs are detected in two separate single base extension (SBE) multiplex reactions with 29 and 23 SNPs, respectively, using SNaPshot kit, capillary electrophoresis and multicolour fluorescence detection. For practical reasons, only the 29 SBE multiplex reaction was carried out by the participating laboratories. A total of 11 bloodstains on FTA cards including a sample of poor quality and a negative control were sent to the laboratories together with the essential reagents for the initial multiplex PCR and the multiplex SBE reaction. The total SNP locus dropout rate was 2.8% and more than 50% of the dropouts were observed with the poor quality sample. The overall rate of discrepant SNP allele assignments was 2.0%. Two laboratories reported 60% of all the discrepancies. Two laboratories reported all 29 SNP alleles in all 10 positive samples correctly. The results of the collaborative exercise were surprisingly good and demonstrate that SNP typing with SBE, capillary electrophoresis and multicolour detection methods can be developed for forensic genetics.  相似文献   
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Women in policing have been the subject of considerable study for the past 20 years. While women perform as well as men in various patrol assignments and situations, they still face a significant amount of disapproval from the male police personnel population. Citizens, however, have shown a greater acceptance of women in this male-dominated occupation and a greater confidence in women’s abilities to effectively perform difficult patrol tasks. The purpose of the present research is to determine the perceptions that residents of two Kentucky counties have of female patrol officers and if those perceptions affirm previous findings. The socioeconomic foundations for those residents’ perceptions are also examined. The research instrument consisted of 17 closed-ended and matrix questions. Two hundred responses were obtained. The results of this study will indicate the public’s growing acceptance of women in this non-traditional gender role, which is a requisite development for the overall objective of attaining equality and equity for women in police work. Recommendations are presented for the purposes of explaining the inevitable changes in the gender makeup and purposes of police work and the need for police personnel and the public to accept those changes. Winner of 1995 Outstanding Undergraduate Paper Award, Southern Criminal Justice Association  相似文献   
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Corruption     
This article engages with the ways in which corruption has taken centre stage in much development policy making and rhetoric. It argues that there is a need to destabilise ‘taken for granted’ assumptions about what corruption is and how it operates. This means generating an understanding of how meanings of corruption vary, and how this variation is determined by the social characteristics of those engaged in corruption talk. It also means examination of how discourses of corruption and anti-corruption are translated from international to national and local stages – from the anti-corruption ‘establishment’ to the realities of bureaucratic encounters in diverse contexts.  相似文献   
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This article charts the constellation of vision and research that underpin a new era in the Family Court of Australia, focusing on the development and outcomes of two programs that have attempted to meaningfully reinforce the centrality of children's rights and needs in family court proceedings. The Less Adversarial Trial and its front‐end Child Responsive Program (CRP) both aim to minimise the potentially negative effects on parents of a litigation process by application of a more intensive case management model adopted with the intention of altering the parents’ experience of the journey. Key features of this approach include the adoption of inquisitorial techniques, which include direct consultation with children through the CRP, modified application of the rules of evidence, and strong judicial management rather than being party driven. Findings from two studies into the pilot Children's Cases Program (now the Less Adversarial Trial) and the CRP are discussed. Significantly, evidence is outlined around the capacity of the new processes to impact on both the co‐parenting and parent–child relationships and to influence short‐term adjustment of complex families in high‐conflict dispute. In encouraging a more active focus on children's needs and views and by facilitating a stronger voice for children in proceedings that affect them, both initiatives advance Australia's commitments under the United Nations Convention on the Rights of the Child.  相似文献   
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