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The problem of single parent/child paternity analysis--practical results involving 336 children and 348 unrelated men

In a certain amount of paternity investigations, only DNA from child and alleged father is analyzed, thus increasing the possibility of false paternity inclusions. The aim of this study was to determine how many wrong paternity inclusions could be detected in a rather small geographical area comparing empirical results from 336 children and 348 men (13-15 STRs were investigated per person). This comparison between each child and all unrelated men (i.e. all putative fathers from the other cases) with an especially designed computer program resulted in 116,004 man/child pairs. Less than three excluding STRs were found in 1666 child/unrelated man pairs (1.44% of the comparisons). At least one unrelated man with only two or less STR mismatches could be determined for 322 children (95.8% of all investigated children). In 26 comparisons no STR mismatches between a child and an unrelated man were detected, thus at least one and up to three "second father(s)" under 350 men could be found for 23 children, if the mother is excluded. Paternity probabilities between 95.475% and 99.996% were calculated. Our results underline the difficulties in motherless paternity cases using only STR analysis and advise great precaution in assigning verbal predicates such as "paternity proven" in those investigations.     

Alternative Ulster? Political Parties and the Non-constitutional Policy Space in Northern Ireland

This article uses data from a survey of the candidates in the 2003 Northern Ireland Assembly election to measure the policy positions of the Northern Irish political parties on scales that are the usual measurements of party policy in Western Europe, such as on economic and social issues, the European Union, morality issues, environmental issues and minority groups. These data were then used to test whether the Northern Ireland party system was conducive to integration or consociationalism, which is the current debate on conflict resolution in Northern Ireland. It argues that this debate has been under-theorised and that empirical data can be used to test the likelihood of either scenario. It concludes that, in most aspects, the Northern Ireland party system tends towards the consociational scenario but there are, nevertheless, aspects which suggest that an integrationist scenario could be produced in the long term.     

Determination of cathinone,cathine and norephedrine in hair of Yemenite khat chewers

A sensitive and reproducible method for the quantitative determination of cathinone (CTN), norpseudoephedrine (NPE, cathine) and norephedrine (NE) from hair was developed. The compounds were extracted for 4 hours with phosphate buffer pH 2.0, followed by a standard solid phase extraction procedure on a mixed phase column, derivatization with heptafluorobutyric anhydride (HFBA) and GC-MS separation and quantification using D(3)-ephedrine (D(3)-E) and alpha-aminoacetophenone (AAP) as the internal standards. The diastereomers NPE and NE were satisfactorily separated. In the validation, the limits of detection and of quantification were determined at 0.03-0.08 ng/mg and 0.10-0.24 ng/mg, respectively and the interday standard deviation was between 10 and 15%. The method was applied to hair samples of 24 Yemenite khat chewers. All three compounds were detected in 23 of these cases. The concentrations ranged from 0.57 to 23.9 ng/mg for NPE, 0.19-25.0 ng/mg for NE and 0.11-22.7ng/mg for CTN. A highly significant correlation was found between the self-reported data about the khat consumption habits of the volunteers (4-56h chewing per week) and the concentrations of norephedrine and norpseudoephedrine in hair.     

Regional Leaders in the Diffusion of Tort Innovations among the American States

Many studies have analyzed the diffusion of legislative policies,but relatively little work has been done on the spread of judicialinnovations. An analysis of the spread of eight tort doctrinesamong the American states indicates that there were clear regionalleaders, including some states that were not early adoptersof the innovations but still served as leaders for their neighbors.There was little relationship between being a regional leaderfor legislative adoptions and being a regional leader in judicialadoptions, indicating that different processes influenced diffusionin these two arenas of state political activity.     

Validity Beliefs and Ideology Can Influence Legal Case Judgments Differently

Jurors sometimes enter a case both with prior beliefs about its likely validity and with more general ideologies that are relevant to the case. Although prior validity beliefs may serve as heuristics, directly biasing decisions when cognitive capacity is low, we hypothesized that ideology may bias systematic thought even when cognitive capacity is high. This experiment studied simulated individual juror decisions in a sex-discrimination case, measuring validity beliefs about such cases as well as feminist ideology, and exposing participants to 1 of 3 case versions under time pressure or no time pressure. Validity beliefs had a direct, heuristic impact on judgment only under time pressure. However, feminist ideology had a mediated influence on judgment via valenced thoughts about the evidence, even under no time pressure. Also, people with initially proplaintiff beliefs judged a woman's sex-discrimination suit more negatively than did prodefendants if the evidence was weak. The results suggest that when jurors can fully process information, validity expectancies might backfire if not supported by case evidence, but ideology can have a more pervasive influence on the decision-making process.     

Y-chromosomal STR haplotypes in Macedonian population samples

Eleven Y-chromosomal short tandem repeats (STRs), DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439 were typed in DNA samples from Macedonian population (n = 150).     

Evaluation of haplotype discrimination capacity of 35 Y-chromosomal short tandem repeat loci

The haplotype discrimination capacity of the 9 Y-chromosomal short tandem repeat (Y-STR) loci comprising the so called minimal haplotype together with additional 26 recently described single-copy Y-STRs was evaluated within 391 males from Germany, The Netherlands, and Turkey. The aim of this study was to identify the minimum number of Y-STRs needed in addition to the recommended 9 minimal haplotype loci or the 11 SWGDAM loci for individualizing male lineages. Highest gene diversities were shown for DYS385 loci, DYS449, DYS481, DYS570, DYS447, DYS576, DYS389-II, and DYS390 (D=0.7518-0.8746). The five Y-STRs DYS447, DYS449, DYS481, DYS570, and DYS576 comprised the smallest set of loci in addition to the previously recommended standard Y-STRs leading to the individualization of all males from each single population group. Complete resolution of the pooled population was achieved by the additional genotyping of two further loci, DYS446 or DYS505 and DYF406S1 or DYS522.