Social science research and experimentation in Australian criminal proceedings: prejudicial pre-trial publicity and psychological research

Using the decision of Barr J in Attorney-General (NSW) v John Fairfax Publications [1999] NSWSC 318, the authors analyse the need for external validity and relevance in social science evidence adduced in the courts. They argue in favour of the rigour employed within Barr J's judgment and contend that a constructive legacy of the decision should be a greater sensitisation on the part of researchers to the kinds of factors that can distance experimental scenarios from curial contexts to a point where generalisations from the former become strained and even spurious. A number of these considerations have the potential to be addressed to a significant extent by improved methodologies. However, the authors warn against an excess of purist fervour in demanding complete comparability of scenarios, lest the fruits of social science be denied to the courts and decision-making be adversely affected by the absence of expert insights falling short of complete replication of conditions between experiments and forensic reality.     

An improved method for post-PCR purification for mtDNA sequence analysis

Mitochondrial DNA (mtDNA) analysis of forensic samples typically is performed when the quantity and quality of DNA are insufficient for nuclear DNA analysis or when maternal relatives may be the only reference source. Many of the steps required in the analytical process are both lengthy and labor intensive. Therefore, improvements in the process that reduce labor without compromising the quality of the data are desirable. The current procedure requires purification of the amplicons by centrifugal filtration after PCR and prior to cycle sequencing. Because this method requires several manipulations to perform, alternate cleanup procedures were investigated. These include the use of 1) Qiagen QlAquick PCR Purification columns, 2) Concert Rapid PCR Purification columns, and 3) ExoSAP-IT reagent. When the yield of purified amplicons, quality of the sequence profile, and ease of assay were evaluated, the use of ExoSAP-IT reagent for post-amplification purification was chosen to replace the filtration method.     

Assisting altruism: evaluating legally binding consent in organ donation policy

The growing need for organ and tissue transplants has led a number of states to enforce a policy that views a donor's declared intent to be an organ donor as legally binding. This allows health officials to harvest organs without the permission of the next of kin. Legally binding consent is controversial because of concerns that it may anger family members, lead to negative publicity, and discourage potential donors. We use interviews and a pooled time-series data set of cadaveric donation rates in U.S. states to evaluate the effectiveness of this policy. Our research indicates that enforcement of legally binding consent has marginally increased cadaveric donations while not significantly affecting donor registration. We also find evidence that the effect of the policy might be greater if it were more fully implemented and coordinated with efforts to improve public acceptance and awareness.