High prevalence of 6-acetylmorphine in morphine-positive oral fluid specimens

Identification of 6-acetylmorphine, a specific metabolite of heroin, is considered to be definitive evidence of heroin use. Although 6-acetylmorphine has been identified in oral fluid following controlled heroin administration, no prevalence data is available for oral fluid specimens collected in the workplace. We evaluated the prevalence of positive test results for 6-acetylmorphine in 77,218 oral fluid specimens collected over a 10-month period (January-October 2001) from private workplace testing programs. Specimens were analyzed by Intercept immunoassay (cutoff concentration=30 ng/ml) and confirmed by GC-MS-MS (cutoff concentrations=30 ng/ml for morphine and codeine, and 3 ng/ml for 6-acetylmorphine). Only morphine-positive oral fluid specimens were tested by GC-MS-MS for 6-acetylmorphine. A total of 48 confirmed positive morphine results were identified. An additional 107 specimens were confirmed for codeine only. Of the 48 morphine-positive specimens, 32 (66.7%) specimens were positive for 6-acetylmorphine. Mean concentrations (+/-S.E.M.) of morphine, 6-acetylmorphine and codeine in the 32 specimens were 755+/-201, 416+/-168 and 196+/-36 ng/ml, respectively. Concentrations of 6-acetylmorphine in oral fluid ranged from 3 to 4095 ng/ml. The mean ratio (+/-S.E.M.) of 6-acetylmorphine/morphine was 0.33+/-0.06. It is suggested that, based on controlled dose studies of heroin administration, ratios >1 of 6-acetylmorphine/morphine in oral fluid are consistent with heroin use within the last hour before specimen collection. The confirmation of 6-acetylmorphine in 66.7% of morphine-positive oral fluid specimens indicates that oral fluid testing for opioids may offer advantages over urine in workplace drug testing programs and in testing drugged drivers for recent heroin use.     

Islam,immigration and group recognition 1

Islam generally, and Muslim immigrant communities in particular, have recently been targeted for criticism by Western academics and in popular Western media. This article explores the substance of these criticisms and weighs them against the beliefs and practices of Muslim immigrants in Western liberal democracies. The article addresses three distinct questions. First, what sorts of cultural adaptations is it reasonable for liberal democratic states and societies to expect immigrants to make, and what kinds of adaptation is it unreasonable to demand? Second, how vulnerable are Islamic beliefs and practices to the criticisms commonly leveled against them in the name of liberal democracy and gender equality? Finally, how strong are the parallels between the claims for political recognition and accommodation that issue from immigrant cultural communities and the claims for recognition and inclusion that issue from groups that have historically been marginalized within liberal democratic societies? Although the authors do not dismiss the notion that there may be tensions between the core commitments of liberal democratic societies and some Islamic practices, they conclude that these tensions are exaggerated by Western writers. Muslim communities generally pose no greater challenge to liberal societies than do other religious and immigrant communities. Western writers should be chary of rejecting their claims to toleration and accommodation too swiftly.     

The theory of economic regulation and public choice and the determinants of public sector bargaining legislation

In this study we used the theory of economic regulation and public choice to derive a model to explain the pattern of public sector bargaining laws among the states. We find this type of legislation is influenced by the following demand factors: (1) the extent of public sector union membership, which represents the interest group hypothesis, has a positive influence on pro-union legislation; (2) the extent of employer opposition to unions, as measured by unfair labor practice charges against employers in representation elections, has a negative effect on bargaining laws; (3) two taste variables — the salaries of public employees and the percent of nonwhite employment in the state — have a positive influence on these laws. A result which will be surprising to many people is that the extent of private sector union membership has no significant influence on the passage of public sector bargaining legislation.Our empirical analysis indicates that supply factors are also important in explaining the pattern of public employee bargaining laws across the state. We find that states are more likely to enact pro-union legislation under the following conditions: (1) constituents appear to hold pro-labor views as represented by their Congressmen's voting record; (2) neighboring states have passed mandatory bargaining laws; and (3) when competition is greater among the political parties.     

Fast Discrimination of Marijuana using Automated High-throughput Cannabis Sample Preparation and Analysis by Gas Chromatography–Mass Spectrometry

In the United States, federal law and many state laws differentiate between marijuana and industrial hemp through delta-9-tetrahydrocannabinol (THC) levels, whereby the latter is defined as ≤0.3 percent THC on a dry weight basis. Many traditional cannabis identification methods employed by crime laboratories cannot accurately determine total THC quantities in accordance with federal and state regulations, or do so with increased time, labor, and risks of instrument damage. In order to quickly distinguish positive marijuana samples, a method was developed to identify plant material with a total THC level >1%. This novel, automated dispersive pipette extraction (DPX) method uses tip-based technology and an automated liquid handler to enable fast, hands-free selective isolation of THC and its precursors for downstream gas chromatography–mass spectrometry (GC-MS) analysis. The workflow proceeds with no repetitive manual effort and reduced need for instrument maintenance while enabling crime labs to legally identify marijuana through the detection of total THC above 1%. Recovery of THC using the DPX extraction method was 93% at 30 µg/mL and 78% at 500 µg/mL. Similarly, THCA-A recovery was 100% at 30 µg/mL and 74% at 500 µg/mL. Samples evaluated in a blind study (proficiency, hemp, and nonprobative case samples) were all accurately identified as greater than or less than 1% THC, with samples containing <1% THC being identified as “cannabis” and subjected to more discriminative analysis as needed.     

The prevalence of compassion fatigue,compassion satisfaction and perceived stress,and their relationships with mental toughness,individual differences and number of self-care actions in a UK police force

ABSTRACT

Police personnel are likely to be affected by stress and compassion fatigue, which may have important consequences for health, well-being and job performance. There are certain individual differences which may protect against compassion fatigue, for example mental toughness, personality and self-care behaviours. However, there is little research examining all of these constructs in combination with policing. The current study aimed to gather information regarding the prevalence of compassion fatigue, compassion satisfaction and perceived stress within a large UK police force, and their relationships with personality, mental toughness and self-care activities. A questionnaire was completed by 605 police employees within a UK police force. The results demonstrated that 20% of personnel suffered from negative psychological outcomes and that these outcomes were predicted by individual differences and self-care activities. The requirement for shift work, and mental toughness scores, significantly predicted compassion satisfaction, compassion fatigue and perceived stress. The analyses also revealed a role for gender, tenure, personality and self-care in several aspects of well-being. The implications of these findings are discussed, considering the current contexts in which policing operates, with the aim of improving the psychological well-being of police officers and staff.     

Factor Structure and Criterion Validity of the Five Cs Model of Positive Youth Development in a Multi-University Sample of College Students

Journal of Youth and Adolescence - There is growing recognition that clinical and developmental outcomes will be optimized by interventions that harness strengths in addition to ameliorating...     

Empowering women through the positive birth movement

Childbirth has been positioned as a life changing event that has profound long-term psychological effects upon women. This paper adopts a community psychology approach to explore the role that the Positive Birth Movement (PBM) may have in tackling negative birth experiences by supporting women before and after birth. Six women who all regularly attend UK-based PBM meetings and had given birth to at least one child participated in one to one semi-structured interviews designed to explore the support they received before, during and after their birth, as well as their experiences with the PBM. A Foucauldian inspired discourse analysis explores themes relating to the lack of support and information provided by the NHS and the function of the PBM as a transformative community space which offers social support and information. Within these themes a focus on neoliberalism, choice and the woman’s position as an active consumer of health care is critically discussed. It is argued that the PBM has the potential to prepare women for positive birth experiences but more attention needs to be paid to the wider contexts that limit women’s ability to make ‘free’ choice.     

Parental Knowledge and Youth Risky Behavior: A Person Oriented Approach

Most studies isolate the effects of one knowledge-related behavior on youth outcomes. This study explores the relationship between subgroups of mother–youth dyads that use specific combinations of parental knowledge-related behaviors and youth risky behavior. Using a sample of 796 rural 6th graders (53 % female), we assessed mother and youth reports of maternal knowledge, active parent monitoring efforts, youth disclosure, parental supervision, and the amount of parent–youth communication to identify five knowledge latent classes: High-Monitors, Maternal Over-Estimators, Low-Monitors, Communication-Focused, and Supervision-Focused. Delinquency, antisocial peers, and substance use were associated with increased odds of membership in the Supervision-Focused class, relative to the High Monitors. Membership in the Low Monitors and Maternal Over-Estimators classes was associated with unhealthy attitudes towards substances and for Low Monitors, substance use. The discussion focuses on the value of using a person-oriented approach to understand parental knowledge and risky behavior during early adolescence and intervention implications.