Umbilical cord blood banking: beyond the public-private divide

Umbilical cord blood is a source of haematopoietic progenitor cells, which are used to treat a range of malignant, genetic, metabolic and immune disorders. Until recently, cord blood was either collected through donations to publicly funded cord blood banks for use in allogeneic transplantation, or stored in commercial cord blood banks for use in autologous transplantation. The line between public and private cord blood banking is being blurred by the emergence of "hybrid" models that combine aspects of both the public and private systems. The authors describe these hybrid models and argue that their emergence is explained by both market forces and public sector policy They propose that the future of the sector will depend heavily on several key developments that will differentially affect public, private and hybrid banking models.     

Incidental findings in human subjects research: what do investigators owe research participants?

The use of brain imaging technology as a common tool of research has spawned concern and debate over how investigators should respond to incidental findings discovered in the course of research. In this article, we argue that investigators have an obligation to respond to incidental findings in view of their entering into a professional relationship with research participants in which they are granted privileged access to private information with potential relevance to participants' health. We discuss the scope and limits of this professional obligation to respond to incidental findings, bearing in mind that the relationship between investigators and research participants differs fundamentally from the doctor-patient relationship.     

Correlates of subjective stress among drug court clients

Psychosocial stress is consistently found to promote initiation, intensification, and relapse in drug abuse. It would, therefore, be desirable to identify characteristics of offenders who are at heightened risk for stress-induced exacerbations of addictive behavior. In this cross-sectional, correlational, interview study, 500 clients of two Kentucky drug courts averaged 30 years of age and were predominantly male, White, employed, high school educated, single, and adjudicated in small- and medium-size cities. Five independent correlates of greater subjective stress emerged in stepwise multiple regression analysis (R2 = .395): use of escape-avoidance coping, positive reappraisal coping (inversely associated), more negative life events, better self-rated health (inversely associated), and access to social support related to work problems (inversely associated). Treatment interventions emphasizing effective coping styles and building of social support as well as managing of negative life events and perceptions of health may serve to lessen subjective stress and its consequences in drug-abusing criminal populations.     

Child physical abuse and self-perceived social isolation among adolescents

This research examines the connection between physical abuse and social isolation. Using data from the National Youth Survey, a measure of self-perceived social isolation was constructed indicating the extent to which respondents feel detached from their friends and from school. Those who had experienced violence were predicted to be more isolated than those who had not. Results strongly supported the hypothesis, controlling for theoretically relevant variables. Explanation is provided in terms of damage to attachment skills, social competence, and self-esteem concomitant to being a victim of abuse. Males were more socially isolated than females, and Hispanics more than Whites. Children with involved parents were less socially isolated; those whose parents experienced normlessness were more isolated. Children who recently experienced a stressful event or were from riskier neighborhoods were more isolated. The number of children in the family was positively related to isolation. Social isolation decreases between seventh and eighth grades.     

Media frenzy greets release of Newfoundland man from prison

Sensationalist media coverage greeted the release of a man convicted more than a decade ago for spreading HIV in Conception Bay North. Concerns have been expressed that the extensive coverage of the release will further stigmatize all people living with HIV/AIDS.     

Does a more centralized urban form raise housing prices?

This paper examines the relationship between various quantitative measures of urban centralization and urban housing prices through the use of a 2000 data set from the 452 Census designated urbanized areas in the United States. An empirical study of this type is necessary because: (1) the theoretical influence of creating more centralized urban areas—or what many would consider less “sprawl”—on what people pay for housing is indeterminate, (2) now popular “Smart Growth” policies advocate more centralized urban areas, and (3) some have argued that a cost of this centralization is an increase in the price of homes. After controlling for differences across United States urbanized areas in residents' economic status and demographics, number and type of households, climate, household growth, nonresidential land uses, and the structural characteristics of houses, we find that a more centralized area exhibits a lower median home value and percentage of homes in an upper‐end price category. Therefore, we offer no evidence to support the contention that a successful effort to further centralize an urban area raises the price of homes in that urban area. © 2006 by the Association for Public Policy Analysis and Management