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181.
Huberfeld N 《Journal of health law》2007,40(2):241-265
The pharmaceutical industry has been receiving greater scrutiny lately due in large part to the many public and private legal enforcement actions taken against pharmaceutical manufacturers. These enforcement actions, along with legal developments such as the OIG Compliance Guidance for Pharmaceutical Manufacturers, the Sarbanes-Oxley Act's statutory guidelines for public corporations, the HIPAA privacy regulations, and the Medicare Modernization Act, have the potential to encourage the pharmaceutical industry to self-regulate beyond the bounds currently required by the law. After a brief overview of enforcement actions and compliance programs directed toward the pharmaceutical industry, this Article reviews a similar situation the hospital industry faced when Medicare promulgated major reimbursement modifications. The Article proposes that the pharmaceutical industry, in the face of such intense scrutiny and uncertainty, should implement more rigorous self-regulation. Without more stringent self-regulation, this intense interest in the pharmaceutical industry may result in a regulatory push that establishes unanticipated and cumbersome measures for the industry. 相似文献
182.
Alex Watson 《Journal of Indian Philosophy》2010,38(3):297-321
The article considers what happened to the Buddhist concept of self-awareness (svasa?vedana) when it was appropriated by ?aiva Siddhānta. The first section observes how it was turned against Buddhism by being used to attack the momentariness of consciousenss and to establish its permanence. The second section examines how self-awareness differs from I-cognition (ahampratyaya). The third section examines the difference between the kind of self-awareness elaborated by Rāmaka??ha (‘reflexive awareness’) and a kind elaborated by Dharmakīrti (‘intentional self-awareness’). It is then pointed out that Dharmakīrti avails himself not only of intentional self-awareness but also of reflexive awareness. Some remarks on the relationship between these two strands of Dharmakīrtian Buddhism are offered. The conclusion points out that although self-awareness occurs in Buddhism as inextricably linked with anātmavāda, the doctrine of no-self, and sākāravāda, the view that the forms we perceive belong not to external objects but to consciousness, it is used by Rāmaka??ha to refute both of these views. An appendix addresses the problem of how precisely to interpret Dharmakīrti’s contention that conceptual cognition is non-conceptual in its reflexive awareness of itself. 相似文献
183.
Nicole L. Ledbetter M.S. Barbara L. Walton B.S. Pedro Davila B.S. William D. Hoffmann B.S. Richard N. Ernest B.S. Guido F. Verbeck IV Ph.D. 《Journal of forensic sciences》2010,55(5):1218-1221
Abstract: This article presents the novel instrumentation of nanomanipulation coupled to nanospray ionization‐mass spectrometry, which is used to directly probe trace analytes found on individual fibers. The low detection limits and sample volumes associated with nanospray ionization‐mass spectrometry make it the ideal instrument to implement for trace analysis. Nanospray ionization‐mass spectrometry, coupled with the nanomanipulator, allows for the direct probing of trace particulates on fibers. The technique is demonstrated by dissolving an electrostatic particle of cocaine from a fiber, collecting the analyte solution in a nanospray tip, and transferring the tip directly to the mass spectrometer to complete analysis. The utility of this technique is evident through the minimal sample preparation and short analysis time. The use of nanomanipulation coupled to nanospray ionization‐mass spectrometry could improve on current trace particulate analysis by reducing both detection limits and sample size required to complete analysis. 相似文献
184.
185.
Isabelle Montani Raymond Marquis Nicole Egli Anthonioz Christophe Champod 《Science & justice》2019,59(1):1-8
This paper explores procedural mechanisms to resolve differing conclusions when two experts have initially worked independently. These experts can be two human examiners or one of them may be a computer-based model. The resolving process is presented as part of the ACE-V protocol adopted widely in pattern recognition areas (e.g. fingerprints, footwear marks, toolmarks or handwritings/signatures comparisons). It set the conditions of operations and delineates a resolving process that is based on the principles of transparency and detailed argumentations. We predict a gradual but steady introduction of computer-based models in the forensic pattern recognition areas. In our opinion, the rules to resolve differing opinions ought to be articulated and documented in the form of standard operating procedures, before any deployment in casework practice. 相似文献
186.
H. Theodore Harcke M.D. Timothy Monaghan M.D. Nicole Yee B.S. Louis Finelli M.D. 《Journal of forensic sciences》2009,54(5):1123-1126
Abstract: Our objective is to document the recovery of DNA from the spinal cord or surrounding dura mater in 11 cases of severely burned human remains. Radiographs established that portions of charred tissue contained spine segments. Multidetector computed tomography (MDCT) revealed that each spine specimen contained an intact spinal cord remnant. A full DNA profile was obtained from seven specimens using spinal cord dura mater in six specimens and spinal cord medulla in one specimen. A partial profile was obtained from four specimens (spinal cord dura mater, 2; spinal cord medulla, 2). Bone and muscle surrounding the spinal cord appear to insulate nucleic acid containing tissue from critical thermal degradation. The spinal cord, which is easily identified by MDCT examination of remains and easily recovered at the postmortem examination, can be a source of DNA with extraction yields comparable with other tissue sources. Specimens of dura mater are preferable as processing time is faster than bone. 相似文献
187.
Little is known about the correlates of white-collar victimization, and even less is known about white-collar crime reporting. In this article, the extent to which predictors of fraud victimization are the same as the predictors of fraud reporting is examined. Using a national sample of fraud victims, these findings were consistent with prior research in that involvement in risky behaviors and age were found to be important predictors of fraud victimization. Additionally, the specific factors that are influential in predicting fraud victimization appear to vary across offense type. Unfortunately, little was revealed regarding the predictors of the official reporting of fraud victimizations. Future research needs to further unravel the importance of risky behavior in both victimization and reporting, as well as to focus on a broader array of white-collar crimes. 相似文献
188.
Globalization is changing the game of economic development, but the emerging rules and optimal strategies remain somewhat unclear. The Mercedes case discussed in this article illustrates the rough and uncertain nature of this transition. From the perspective of the traditional strategy, the price of the jobs initially promised by Mercedes seemed high; and the ultimate cost was increased by the intense competition among the bidding states. Yet from another perspective, the incentives offered by Alabama can be viewed as “table stakes” for the new global game of economic development. 相似文献
189.
The role of media in promoting political accountability and citizen participation is a central issue in governance debates. Drawing on research into the interactions between radio station owners, journalists, audiences and public authorities during Somali radio call-in programmes we argue that these programmes do not simply offer a new platform for citizens to challenge those who are governing but that they are also spaces where existing power structures reproduce themselves in new forms. We identify the ways the programmes are structured and the different motivations the audience has for participation. Three types of programmes are identified and their relationships with patronage, politics, and performance are examined. Rather than focusing on normative assumptions about the media as a tool of accountability, the article emphasises the importance of understanding radio programmes in their social and political environment, including the overlapping relationships between on-air and off-air networks. 相似文献
190.
Nicole L. Johnson Samantha C. Holmes Dawn M. Johnson 《Journal of family violence》2016,31(8):999-1003
The literature on gender differences in perpetration of physical partner violence (PV) consists of two opposing camps: those who emphasize gender symmetry, and those who emphasize gender asymmetry. We propose a both/and approach to this controversy by suggesting that the issue of gender symmetry is complex and dependent upon context. Furthermore, we discuss how the role of personal investment in political agendas contributes to this divide in the literature. We argue that this both/and approach to inquiry will significantly contribute to the understanding of gender differences in perpetration of PV, as well inform the development of interventions for PV. 相似文献