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Cocaine use and abuse, an ancient custom, is once again commonplace. While severe toxicity appears to be rare, overt poisoning including death can occur. This report documents nine cases of death associated with cocaine use; in three of these cocaine appears to be causative. Toxicologic analysis of body fluids and tissues was affirmative and levels are reported. Cocaine should be considered in serious drug overdose-reactions, especially after illicit injection.  相似文献   
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Influenza A virus infection complicated by fatal myocarditis   总被引:4,自引:0,他引:4  
Influenza virus typically causes a febrile respiratory illness, but it can present with a variety of other clinical manifestations. We report a fatal case of myocarditis associated with influenza A infection. A previously healthy 11-year-old girl had malaise and fever for approximately 1 week before a sudden, witnessed fatal collapse at home. Autopsy revealed a pericardial effusion, a mixed lymphocytic and neutrophilic myocarditis, a mild lymphocytic interstitial pneumonia, focal bronchial/bronchiolar mucosal necrosis, and histologic changes consistent with asthma. Infection with influenza A (H3N2) was confirmed by virus isolation from a postmortem nasopharyngeal swab. Attempts to isolate virus from heart and lung tissue were unsuccessful. Immunohistochemical tests directed against influenza A antigens and in situ hybridization for influenza A genetic material demonstrated positive staining in bronchial epithelial cells, whereas heart sections were negative. Sudden death is a rare complication of influenza and may be caused by myocarditis. Forensic pathologists should be aware that postmortem nasopharyngeal swabs for viral culture and immunohistochemical or in situ hybridization procedures on lung tissue might be necessary to achieve a diagnosis. Because neither culturable virus nor influenza viral antigen could be identified in heart tissue, the pathogenesis of influenza myocarditis in this case is unlikely to be the result of direct infection of myocardium by the virus. The risk factors for developing myocarditis during an influenza infection are unknown.  相似文献   
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Debates about public diplomacy have recently turned to the role of non-governmental organizations (NGOs) in what had been primarily a conversation about state-to-state affairs. We contribute to this conversation through an in-depth analysis of the Asia Society. Founded by John D. Rockefeller III in 1956, the Asia Society was established to educate Americans about Asia at a time when there was much less contact between the USA and Asia. Since then, the institution has undergone several reinventions, each contributing to and reflecting changing understandings of Asia and its relationship to the USA. We track the kinds of artwork the Asia Society collects and puts on display, the range of countries it categorizes as Asian, and the goals and content of its programming to reveal these shifts in scale and focus and demonstrate how they mirror and drive forward shifts in US-Asian relations. We argue that understanding how cultural institutions contribute to changing geographic imaginaries and geopolitics is an important, often overlooked aspect of public diplomacy. They are both a catalyst and reflection of changing political economic dynamics that, in turn, shape how citizens imagine their world and their nation’s place within it.

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Advances in robotic handwriting technology create new challenges for forensic document examiners. In the past, devices such as the autopen were used to replicate signatures of government officials and corporate companies. In today's technology, companies such as Bond utilize robots to create written documents, which mimic natural patterns of handwriting. They generate customizable written samples by simulating pen movements and letter formations. Four forensic document examiners were given various reproduced questioned documents and utilized a modified ACE‐V (analysis, comparison, evaluation, verification) methodology to determine their genuineness. Examiners were able to make a distinction between the human writing samples and the skilled robotic equivalents. Several distinct features that are not seen in natural handwriting, such as even pen pressure and the superimposition of letterforms were observed in the robotic samples. Careful examination of identifying features of the Bond produced documents resulted in an opinion of nongenuineness.  相似文献   
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Limited research exists on the impact of prison mother and baby unit (MBU) residence. Research in the UK suggests women in MBUs have lower prevalence of mental disorder. Higher rates of mother-child attachment for women in prison nurseries in the US have been reported. Eighty-five pregnant women were interviewed at baseline and 62 followed up in nine different prisons. The Edinburgh Postnatal Depression Scale (EPDS) was used to measure perinatal depression; the World Health Organisation Quality of Life (WHOQOL – BREF), for quality of life; and the Mother-to-Infant Bonding Scale (MIBS) for mother-child bonding. EPDS scores were higher at baseline than follow-up. Women admitted to MBUs had lower EPDS scores at baseline and follow-up, and this reduction was greater than for women not admitted to MBUs. WHO-QOL scores were higher at follow-up than baseline on all domains, except the social domain for those not admitted to MBUs. Findings suggest women with perinatal depression are less likely to be admitted to MBUs, and MBU placement may contribute to a reduction in perinatal depression. Increased QOL-BREF scores at follow-up suggest improved quality of life for all participants. Reduced support post-separation may contribute to lower social domain scores for women not admitted to MBUs.  相似文献   
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