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21.
Strano-Rossi S Castrignanò E Anzillotti L Serpelloni G Mollica R Tagliaro F Pascali JP di Stefano D Sgalla R Chiarotti M 《Forensic science international》2012,221(1-3):70-76
New Italian legislation on driving under the influence of drugs considers oral fluid (OF) as a possible alternative drug testing matrix. On this basis, the present research was carried out to evaluate the applicability of four commercial on-site OF drug screening devices, namely DDS(?), Drugtest 5000(?), Drugwipe 5+(?) and RapidSTAT(?), in a real operative context. Preliminarily trained police officers tested randomly stopped drivers with two different kits side-by-side during roadside patrols. A central laboratory confirmed on-site kits' results by UHPLC-MS/MS analysis of the saliva specimen remaining after the screening analysis. 1025 drivers were submitted to the OF tests: 11.6% were positive for cocaine and metabolites, 11.1% for THC, 6% for amphetamines and amphetamine-type designer drugs and 2.3% for ketamine. The sensitivities of the kits were 81% (RapidSTAT(?)), 82% (DDS(?)), 90% (Drugwipe 5+(?)) and 97% (Drugtest 5000(?)) for cocaine and 38% (DDS(?)), 47% (Drugwipe 5+(?)), 72% (RapidSTAT(?)) and 92% (Drugtest 5000(?)) for THC. Drugtest 5000 was the only kit showing an acceptable sensitivity for on-site application. Only Drugtest 5000(?) and RapidSTAT(?) could be evaluated for amphetamines and methamphetamines: Drugtest 5000(?) showed a sensitivity of 100% in the case of amphetamines and 86% for methamphetamines, while RapidSTAT(?) 90% and 76% respectively. Nowadays, ketamine is not included in the target analytes of any on-site devices, but it was systematically included in the UHPLC-MS/MS confirmatory analysis. To ensure adequate reliability, MS confirmation of on-site OF screening tests is anyway always necessary, due to the presence of a significant number of false positive results even when using the commercial kit with the best performance. 相似文献
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Municipal Support for Social Entrepreneurship 总被引:3,自引:0,他引:3
This study examines how cities help social entrepreneurship—the activity of private individuals and organizations taking initiative to address social challenges in their communities. Based on a national survey and in-depth interviews among jurisdictions with populations over 50,000, the authors find that municipalities help social entrepreneurs by increasing awareness of social problems, and by helping them to acquire resources, coordinate with other organizations, and implement programs. Nearly three-quarters of cities provide active or moderate support, which is positively associated with the perceived effectiveness of nonprofit organizations in their communities. 相似文献
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This article examines Navajo Indian representation on the governingboards of six county governments in Arizona, New Mexico, andUtah. External pressures, especially decisions by the federalgovernment, have encouraged increased Navajo representationand changes in county policies that benefit people on the reservation.Beyond this, the findings for individual counties are consistentwith previous research in suggesting that the size of the Navajopopulation as a percentage of the county population is an importantfactor affecting Navajo success in winning seats and the allocationof benefits to reservation residents. Yet, opposition to Navajorepresentation, the ability of Navajos to secure office, andthe policy significance of their representation are far morecomplex than usually suggested by the relevant literature basedlargely on black and Hispanic experiences. 相似文献
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Sabina Low Joshua R. Polanin Dorothy L. Espelage 《Journal of youth and adolescence》2013,42(7):1078-1089
Despite the veritable influence of the peer context on the elaboration of adolescent aggression, few studies of relational aggression have directly identified and measured peer groups, limiting our ability to draw formal conclusions about the level and nature of peer influence. The current study used a developmental framework to examine peer group influence on individual levels of physical and relational aggression over a year with 6th and 7th grade students (n = 346, 51 % female). A multilevel network approach was used in which peer groups were identified via social network analysis, and peer group influence was evaluated with hierarchical linear modeling (HLM). HLM analyses indicated that peer group aggression (physical and relational) at time 1 was predictive of individual aggression levels at time 2 after controlling for other peer group characteristics as well as other individual risk and protective factors. Although both forms of aggression were embedded in peer networks, findings suggest that physical aggression is relatively less endemic to peer networks, and is more likely to occur in smaller, predominantly male networks. The current study highlights the importance of understanding the influence of peer group membership on adolescent aggression and points to important implications for prevention. 相似文献
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This study assesses perceptions of managerial emotional intelligence in local government, as well as the practices and polices affecting it. Though few cities offer training programs for managers that are called "emotional intelligence," many cities engage in activities that target or address EI skills. This study finds improvement opportunities for managers to become better attuned to the feelings of others and themselves, to better know their own strengths and weaknesses, to better deal with their negative emotions and increase their adaptability, and to improve their communication and relationship skills. Feedback and mentoring processes are directly associated with increased perceptions of EI, while other practices such as training, selection and policy development are only indirectly associated with perceptions of EI. This study contributes to the knowledge base by increasing awareness about managerial EI skills, and providing specific examples of practices to further managerial EI. 相似文献
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Although trial attorneys typically choose to have defendants testify on their own behalf, there are data from studies using simulated juries which suggest that the presentation of favorable testimony by defendants might be harmful. Data from these studies are suspect, however, because subjects' verdicts had no realworld consequences. In the present study the real-world consequentiality of subjects' verdicts (some vs. none), the presence of mitigating testimony (some vs. none), the source of the mitigating testimony (defendant vs. third party), and the credibility of mitigating testimony (high vs. low) were all manipulated in order to test their effects on the severity of penalities subjects assigned. The results showed that among subjects whose decisions were of no consequence, none of the other manipulated variables produced any reliable differences. On the other hand, among those who thought their decisions were of real consequence, less severe penalties were given when mitigating testimony was presented as opposed to when it was not, and more interestingly, this was true regardless of the testimony's source. The results are seen as underlining the importance of inducing a sense of consequence in simulated jury studies. 相似文献