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391.
In this article, I probe an example of high‐technology medicine as a case study in the problems of the regulation of advancing technology. Specifically, I address the implications of pharmacogenomics—an emerging form of population‐based health care intervention—for public policies designed to eliminate racial disparities in health. Using the case of BiDil, a historical precursor to pharmacogenetic technology, I offer a framework for further studies of high‐technology medicine in which policy analysis is part of a social review based on the justice standard of ex ante mutual advantage. It is the contention in this article that the most just and reasonable deployment of pharmacogenomics is as a compensatory tool to alleviate health disparities.  相似文献   
392.
Thousands of Central American families are fleeing from violence in their own countries and seeking protection in the US. However, once they enter the country they are immediately confined in temporary holding cells – also called hieleras (iceboxes) due to their extremely low temperatures, where they undergo violence and neglect. The hieleras become the site where the categories of the asylum-seeker, the immigrant, and the criminal become conflated. Asylum-seekers entering the country also enter an already existing racialized structure where Latina/o subjects have been criminalized. This article analyzes the hieleras through a Foucauldian and a transnational feminist lens, and argues that these holding cells work as a site for punishing border crossers and deterring them (and others like them) from pursuing the asylum process; which are displays of both sovereign power and disciplinary power.  相似文献   
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Adverse childhood experiences and pessimistic future expectations about college attendance or mortality are established risk factors for problem behaviors among youth. Data were from the National Longitudinal Study of Adolescent to Adult Health (N?=?14,800; 49?% female). Participants were 11–17-years-old at baseline and 24–32-years-old at outcome. Adolescents’ college expectations and fatalistic expectations mediated the effect of childhood adversity on violent behavior in young adulthood. Neither college nor fatalistic expectations were significant mediators in models predicting substance use and nonviolent antisocial behaviors. Although observed mediational effect sizes were small, they survived models that included multiple controls designed to rule-out alternative explanations. Intervening on adversity-exposed adolescents’ college and fatalistic expectations may reduce risk for violent behaviors.  相似文献   
395.
Hopeful expectations for the future have been shown to play an important role in the positive development of youth, including youth contributions to society. Although theory and some research suggest that familial socialization may influence future-oriented cognitions, little work has focused on the possible interrelation of parent–child relationships and the development of hope, particularly during adolescence. Accordingly, the first goal of this study was to identify developmental profiles of youth with respect to hopeful future expectations (HFE) and parental trust across adolescence. Next, we explored whether these developmental trajectories were related to youth Contribution, indexed by community leadership, service, and helping attitudes and behaviors. We used growth mixture modeling to simultaneously examine trajectories of adolescents’ perceived connections with parents (indexed by parent trust) and HFE among 1,432 participants (59 % female) from Waves 3 through 6 (Grades 7 through 10) of the 4-H Study of Positive Youth Development. A four-profile model provided the best fit to the data, with the following profiles: Moderate HFE/U-shaped Trust; Moderate HFE/Increasing Trust; Both Decreasing; and Both High Stable profiles. We then explored whether hope-trust profiles were related to youth Contribution in Wave 7. Contrary to hypotheses, results indicated that the profile reflecting the greatest discrepancy in HFE and trust across early to middle adolescence (i.e., Moderate Hope/U-shaped Trust) was associated with the highest mean Contribution scores. The implications of the findings for future theory and research are discussed.  相似文献   
396.
ABSTRACT

Over the last two decades, the expansion of oil palm and sugarcane plantations in the Polochic Valley (Guatemala) has exacerbated the historical struggle of Maya-Q’eqchi’ peoples for land rights. Based on a mixed-methods approach, I examine the dynamics of the conflict between 1998 and 2014, focusing on the visibility, manifestation and intensity of violence and the role of Non-Governmental Organizations (NGOs) and peasant organizations in opposition to oil palm and sugarcane plantations. I show that the evolution of the conflict can be explained by changes in the strength of organizations' alliances due to tensions and lack of coordination, as well as the fear of state repression and the funding context of these organizations. These results allow me to discuss how violence, the role of these organizations and the dynamics of related events have influenced the visibility of the conflict associated with the expansion of oil palm and sugarcane plantations in the Polochic.  相似文献   
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As is well known, women labored under severe disabilities in the Renaissance court system. It was especially difficult for married women to litigate on their own behalf. Widows litigated more frequently, often to address issues of property or inheritance. To date, little attention has been given to the depiction of women at trial in the plays of the period. Unexpectedly, when we look at the trial scenes in the plays, the women are anything but shy and retiring. In the trial scenes examined, married women litigants prove to be forceful advocates of their position, often accusing hegemonic figures of injustice and unfair process. In conclusion, it is suggested that through the vehicle of presumptively vulnerable women defendants, the playwrights could dramatize the problem of overbearing, partial judges, and other problems that plagued the Renaissance legal system.  相似文献   
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