Sudden cardiac death due to giant cell inflammatory processes

Granulomatous inflammation of the myocardium may occur in a number of systemic disease processes including those with infectious etiologies such as fungal, mycobacterial and parasitic infections, as well as hypersensitivity reactions, and rarely autoimmune disorders. In many of these disorders, giant cells are components of the inflammatory infiltrate. Systemic granulomatous processes of unknown pathogenesis, most notably sarcoidosis, may also be associated with involvement of the myocardium. Occasionally, these disorders are associated with sudden death due to pathologic involvement of the heart. In contrast, giant cell myocarditis, also known as idiopathic myocarditis, a rare, frequently fulminant and fatal disorder of unknown etiology, is isolated to the heart and lacks systemic involvement. This disorder is most commonly diagnosed at autopsy. We present two cases in which sudden death resulted from a giant cell inflammatory process affecting the myocardium. Both individuals lacked antemortem diagnoses and collapsed at their respective places of employment. These cases compare and contrast the clinical and pathologic issues involved in the differential diagnoses of the subgroup of sudden cardiac deaths resulting from giant cell inflammatory processes that affect the myocardium, as well as the value of histologic examination and immunohistochemical studies.     

EU GDPR or APEC CBPR? A comparative analysis of the approach of the EU and APEC to cross border data transfers and protection of personal data in the IoT era

This article examines the two major international data transfer schemes in existence today – the European Union (EU) model which at present is effectively the General Data Protection Regulation (GDPR), and the Asia-Pacific Economic Cooperation (APEC) Cross Border Privacy Rules system (CBPR), in the context of the Internet of Things (IoT).While IoT data ostensibly relates to things i.e. products and services, it impacts individuals and their data protection and privacy rights, and raises compliance issues for corporations especially in relation to international data flows. The GDPR regulates the processing of personal data of individuals who are EU data subjects including cross border data transfers. As an EU Regulation, the GDPR applies directly as law to EU member nations. The GDPR also has extensive extraterritorial provisions that apply to processing of personal data outside the EU regardless of place of incorporation and geographical area of operation of the data controller/ processor. There are a number of ways that the GDPR enables lawful international transfer of personal data including schemes that are broadly similar to APEC CBPR.APEC CBPR is the other major regional framework regulating transfer of personal data between APEC member nations. It is essentially a voluntary accountability scheme that initially requires acceptance at country level, followed by independent certification by an accountability agent of the organization wishing to join the scheme. APEC CBPR is viewed by many in the United States of America (US) as preferable to the EU approach because CBPR is considered more conducive to business than its counterpart schemes under the GDPR, and therefore is regarded as the scheme most likely to prevail.While there are broad areas of similarity between the EU and APEC approaches to data protection in the context of cross border data transfer, there are also substantial differences. This paper considers the similarities and major differences, and the overall suitability of the two models for the era of the Internet of Things (IoT) in which large amounts of personal data are processed on an on-going basis from connected devices around the world. This is the first time the APEC and GDPR cross-border data schemes have been compared in this way. The paper concludes with the author expressing a view as to which scheme is likely to set the global standard.     

The Short-Term Dynamics of Peers and Delinquent Behavior: An Analysis of Bi-weekly Changes Within a High School Student Network

Objectives

To analyze short-term changes in peer affiliations, offending behavior and routine activities in order to evaluate three different processes: peer selection, peer socialization and situational peer influences.

Methods

The short-term longitudinal TEENS study was conducted among a cohort of students from one mid-sized high school in Kentucky, as part of the larger Rural Substance Abuse and Violence Project. The study sample consists of one complete network of 155 ninth graders who completed surveys about their peer affiliations, routine activities and offending behaviors over the course of five waves of data collection during the beginning of the school year. The measurement intervals were no more than 2 weeks long. Longitudinal network analysis (SIENA software that enables actor-oriented stochastic modeling) was used to estimate peer selection, socialization, and situational effects.

Results

Peer networks, offending, and routine activities appeared to be very volatile over the research period. Peer selection effects were found for structural network properties, demographics and delinquent values, but not for peer delinquency. We did not find significant peer socialization effects within the research period, but instead found that changes in offending were related to situational changes in unstructured socializing, alcohol use and marijuana use.

Conclusions

The results suggest that traditional time lags of one year or six months between measurements may fail to capture short-term relations between peers and behavior. Long-term peer influence processes like socialization may be less important in the short run, while situational peer effects might be more salient.

     

SIDESTEPPING A QUAGMIRE: RUSSIA,SYRIA, AND THE LESSONS OF THE SOVIET-AFGHAN WAR

Russia's military intervention in Syria (2015-present) has ensured the Assad regime's survival to date. Why though has Russia succeeded in achieving its objective? This article provides an analysis of Russia's involvement in the Syrian civil war in comparison to the Soviet Union's military debacle in Afghanistan (1979-89). Accordingly, by avoiding the USSR's mistakes in Afghanistan, this article posits that Russia has not become entangled in a protracted conflict in Syria. In Syria, Russia has militarily intervened to buttress the Assad regime, not to reorganize the host government's leadership and assume control over the war effort. Meanwhile, Syrian opposition forces lack concerted international support and Russia has allies that are assisting the embattled Syrian government. Lastly, Russia intends to ‘freeze’ the Syrian civil war in place by (i) pressuring opposition forces to submit and other countries to re-embrace Damascus in a diplomatic forum, (ii) endorsing Syria's claim to sovereignty, and (iii) relying upon a small military presence to deter others from destabilizing Assad's rule.     

The tragedy of academic criminal justice

Criminal justice Ph.D. programs in the United States are unusually behavioristic in their structure, concentrating attention on quantitative methodologies and strongly pressuring students to construct studies that utilize acquired skills. As a result, Ph.D. students take on a strongly conservative cast, seldom asking larger, more philosophical questions about the field as a whole and its place in its context, which is that of the American polity. Instead, students look for methodologically manageable problems within the given and accepted system. The result is the creation of a generation of American Ph.D. holders who have practically no critical perspective on the system.     

"For us it is like living in the dark": Ethiopian women's experiences with domestic violence

This article discusses the experiences of domestic violence among Ethiopian refugees and immigrants in the United States. A subset (n=18) of the larger study sample (N=254) participated in three focus groups with Amharic-speaking survivors of domestic violence who were currently in or had left abusive relationships. The research was conducted through a public health department, University, and community agency partnership. Findings show domestic violence as taking place within a context of immigration, acculturation, and rapid changes in family and social structure. Participants expressed a need for language and culture-specific domestic violence support and advocacy as well as education programs regarding U.S. laws and resources.     

Queer pleasures: Some thoughts

Queer praxis is often conceptualized as a creative construction of alternative ways of being; a strategic practice of self‐(trans)formation. The practice of queer pleasures constitutes one such mode of possibility. Within this model, queer pleasures represent the threshold of a politics that promises a radical confrontation with inhibiting normalities. Yet by applying political priorities to pleasure, and by incessantly equating pleasure with the sexual, there is a risk of re‐establishing hierarchies and conventions, and, moreover, of reinforcing a notion of the subject as self‐transparent, autonomous and intentionally motivated. This paper explores some of the dimensions of pleasure that this politics tends to ignore—the trivial, quotidian, accidental, embarrassing, boring, insignificant, mediocre—and asks whether this overlooking is accidental or a structural inevitability. I will explore queer's investment in the politics of pleasure, and speculate about alternatives