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Correlation between plasma and bone marrow tricyclic antidepressants has not been studied before. Two groups of rabbits were given 10 and 20 mg of desipramine/kg body weight, respectively. Desipramine was administered to the animals once daily by mouth for 5 days. On the fifth day the animals were sacrificed and blood and bone marrow samples were collected and analyzed using a high performance liquid chromatographic (HPLC) method. Data showed that a correlation exists between bone marrow and blood desipramine. The bone marrow desipramine concentration increased as its blood levels increased. The average ratio of bone marrow to blood desipramine +/- S.D. (standard deviation) in both dosage groups was 37.2 +/- 4.46 with a range of 30.99-44.82. This investigation is promising and shows that bone marrow could be used as an alternative tissue in the absence of a suitable blood sample. 相似文献
35.
This paper addresses two neglected areas in the research on the relationship between family violence and violence outside the home: violence other than parent-child abuse and the effect of gender. Specifically, we consider both parental and sibling violence as independent variables, nonfamily violence as the dependent variable, and gender as the specification variable. The data were collected from a sample of 306 students in Introductory Sociology and Social Problems classes. The finding of particular importance is that the interaction between the gender of both the aggressor and the victim has a significant effect on the relationship between violence within the home and nonfamily violence. 相似文献
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W D Haglund D G Reichert D T Reay 《The American journal of forensic medicine and pathology》1990,11(1):35-43
The Green River Murder Investigation in King County, Washington, is currently the longest active serial murder investigation in U.S. history. During its course, over 26 separate scenes with from one to five victims each have been processed. The experience of the authors is presented in order to acquaint other agencies with techniques of outdoor scene processing that have evolved during recovery of remains from Green River and other skeletal cases. 相似文献
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The absence of a thoroughly developed, working class critique of criminological theory has resulted in bias in the creation
of knowledge regarding crime and deviance. Much as feminist writings illuminated the unique problems related to gender, and
works by those discussing racial and ethnic minorities highlighted the special concerns related to race and ethnicity, a working
class perspective can expose the particular issues having to do with class. A brief discussion will be presented dealing with
the portrayal of working class people in the media, and the complicity of academia in allowing working class stereotypes to
persist. A sketch of a working class perspective will then be developed, and it will be used to critique fourteen of the major
criminological theories today in terms of their relative sensitivities and considerations of the class factor in crime and
justice issues. The final section places each of the fourteen theories on a continuum from those that do not consider the
working class experience at all to those that give the working class experience full consideration.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
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J W Eisele J Frisino W Haglund D T Reay 《The American journal of forensic medicine and pathology》1987,8(3):208-209
The population-adjusted rate of teenage suicide in King County, Washington, was reviewed for the 26 years from 1959 to 1984. For the entire period, the rate did not change significantly. An abrupt change did occur during the middle of this period, but, for reasons discussed in the text, this may well represent a change in procedures and philosophy of death certification rather than a real change in rate. Reasons for the apparent discrepancy with national statistics are discussed. 相似文献
40.
William V. Pelfrey Jr. 《Journal of criminal justice》2007,35(3):313
Although law enforcement agencies across the nation have assumed part of the responsibility in the fight against terrorism, significant confusion exists as to the role of local law enforcement. While some agencies have taken steps towards terrorism prevention, little data has been collected on which agencies have taken the greatest steps, how those agencies have changed, and how other agencies should direct their activity. This case study of law enforcement census data from a single state considered variations in terrorism preparedness and predictors of preparedness. Agency size, presence of funding, and other variables significantly predict levels of terrorism preparedness. Important policy implications such as the distribution of funding and which agencies should be working towards terrorism preparedness are discussed. 相似文献