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Molecular characterization and Austrian Caucasian population data of the multi-copy Y-chromosomal STR DYS464 总被引:4,自引:0,他引:4
Berger B Niederstätter H Brandstätter A Parson W 《Forensic science international》2003,137(2-3):221-230
DYS464 is a multi-copy STR system with four positions on the Y-chromosome (DYS464a, b, c, and d) which was recently identified and characterized [Forensic Sci. Int. 130 (2002) 97]. The aims of our study were to perform a population study, to estimate the mutation rate and an extensive sequence analysis in order to confirm the nomenclature. Fourteen different alleles were found in an Austrian population sample with an allele length varying from 9 to 19 repeats. All alleles were cloned and sequenced. Alleles 9-19 showed the general repeat structure (CCTT)n...(CCTT)2...(CCTT)3...(CCTT)4...(CCTT)2...(CCTT)2. The nomenclature is based on the number of repeated units of the variable (CCTT)n-stretch only. In 13% of the samples intermediate alleles, namely 14.3A, 14.3B and 15.3 were detected. In these alleles the variable repeat block is interrupted by a CTT motif (14.3A: (CCTT)3CTT(CCTT)11; 14.3B and 15.3: (CCTT)7CTT(CCTT)7/8). A comparison with GenBank entries revealed the existence of a length variant due to a deletion of one cytosine in the 5' flanking region of the first repeat block. We designed an alternative forward primer to circumvent possible ambiguities in the allele designation. A total of 54 different genotypes were identified in 135 men corresponding to a discrimination capacity (DC) of 40% and a gene diversity (GD) of 0.97. These values are much higher than those of other Y-chromosomal short tandem repeats (Y-STRs). DYS464 has the same haplotype diversity (HD) as the combination of the five Y-STR loci with the lowest gene diversities of the Y-STR core set. On the other hand, a combination of the three most diverse loci (DYS464, DYS385 and DYS390) has the same capacity to distinguish between paternal lineages than the complete minimal haplotype (minHT) consisting of eight Y-STR loci. In our population sample the addition of DYS464 to the minHT increases the number of different haplotypes from 110 to 122. The mutation-rate estimate based on the 70 meioses analyzed amounts to 2.86 x 10(-2) (95% confidence interval 3.5 x 10(-3) to 9.95 x 10(-2)). This value is approximately 10 times higher than the average mutation-rate estimate for Y-STRs. 相似文献
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ABSTRACTThis paper studies emerging power configurations in Upper Guinea Coast societies which result from contemporary interactions of global and local models of governance. With empirical data on shifting meanings of chieftaincy and control of land, changing tax regimes and the rising importance of youth in domestic politics, modifications of legitimate authority across time are contrasted with the effects of international interventions and global discourses on socio-political change. Some of these interventions accelerate, others accentuate or counteract processes of change within local power configurations. Only by carefully considering the innate malleability of local concepts of authority, history, and tradition can contemporary processes of change be identified as either mere reconfigurations or genuinely new configurations of power. 相似文献
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Anita M. Weiss 《Citizenship Studies》1999,3(1):141-150
This article makes the argument that when women have organized themselves into groups with a political purpose, we have witnessed significant advancement in the construction of a civil society in Pakistan. It traces the role women's groups have played as intermediary groups, particularly as they play increasingly important political and social roles in countering the actions and inactions of the state. Importantly, it is in the ongoing effort to develop a National Plan of Action in Pakistan in response to the Beijing Platform for Action that women's groups are contributing in a significant way to a participatory, sensitized and increasingly decentralized national planning process which is encouraging regional and NGO inputs in unprecedented ways. 相似文献
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Anita Heber 《Trends in Organized Crime》2009,12(2):122-144
The building industry is a sector characterised by a large number of opportunities to commit economic crime. In Sweden, the
level of tax avoidance in the building trade is estimated to be substantial, and the use of black market labour extensive.
This article focuses on the organised use of black market labour in the building industry, which may be described as a form
of both economic and organised crime. To date only a very small number of criminological studies have examined the use of
black market labour in this sector of the economy. The article focuses on two of the central roles found in the context of
organised, black market labour: the “fixer” and the “criminal entrepreneur”. The fixer is an individual with expertise in
the methods of economic crime. The criminal entrepreneur acts first and foremost as a link between a client and the manpower
required by this client. In this paper, fixers and criminal entrepreneurs are studied on the basis of data from the Swedish
Register of Suspected Offenders. The analysis shows that the networks of fixers and criminal entrepreneurs overlap one another
to some extent. There are nonetheless a number of differences between the two groups and also between their respective networks.
The networks of the fixers are larger than those of the criminal entrepreneurs, and the individuals that comprise the fixers’
networks are suspected in connection with much larger numbers of offences. The fixers more often commit offences together
with others and also have larger numbers of suspected co-offenders than the criminal entrepreneurs. On the other hand, the
criminal entrepreneurs are suspected of having maintained their ties to suspected co-offenders for longer periods of time
than the fixers. The fixers appear to specialise in fraud and forgery offences, whereas motoring offences, smuggling and drug
offences are more common among the criminal entrepreneurs. The networks are highly male-dominated and on balance they are
comprised of much older individuals than those of traditional offenders. Many of the fixers and criminal entrepreneurs are
suspected of committing offences with the same co-offender for a long period of time. Further out in the networks, co-offenders
are replaced more often. Tax offences are very common in both types of network, both in those parts of the network that are
close to the fixers and criminal entrepreneurs, and also in more distant parts of the networks. In the more distant parts
of the networks, there is also an increase in the proportion of offences that individual network members are suspected of
committing. Judging from the material examined in the current study, violent offences do not appear to be very common among
either fixers or criminal entrepreneurs. The networks examined are largely comprised of individuals suspected of economic
offences. These individuals are linked together with one another by means of direct and indirect contacts that produce semi-legal
networks of individuals with knowledge of organised black market labour.
相似文献
Anita HeberEmail: |
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European Journal on Criminal Policy and Research - Illegal commerce in plants and their derivatives threatens and destroys numerous species and important natural resources, and may cause... 相似文献