A rapid and sensitive method for the identification of delta-9-tetrahydrocannabinol in oral fluid by liquid chromatography-tandem mass spectrometry

This paper proposes a new approach for automatic classification of counterfeit Viagra(?) and Cialis(?) tablets using image processing and statistical analysis. A high resolution VSC 5000 is used for image acquisition in a controlled environment, and the combination of a thresholding technique with morphological operators is used to segment the tablet from the background. A statistical model based on the RGB color components of original samples is built, and the detection of counterfeit tablets was performed by checking the adherence of a test sample to the obtained distribution using the Bhattacharyya distance. Our experimental results indicated that counterfeit tablets can be effective detected using the proposed approach.     

Parental problem-solving skills and child behavior problems: A comparison of physically abusive,neglectful, clinic,and community families

Failure to solve problems related to parenting and other aspects of daily living is hypothesized to result in frustration or inability to cope, and lead to deviant parental behavior such as aggression or neglect. The present investigation provided support for a procedure for measuring parental problem-solving skill and compared the problem-solving abilities and child behavior problems of maltreating and nonmaltreating parents. Subjects were 40 parents with at least one child between the ages of three and twelve. Subjects were assigned to one of four groups: (a) physically abusive parents (n = 9); (b) neglectful parents (n = 9); (c) nonmaltreating clinic parents seeking help for child behavior problems (n = 11); and (d) nonmaltreating, non-help-seeking community parents (n = 11). Abusive and neglectful parents were deficient in problem-solving skill as compared to clinic and community parents, yet there were many similarities in parental reports of child behavior problems for maltreating and nonmaltreating parents. Parental problem-solving skill did not correlate significantly with parental ratings of child behavior problems.     

The parental problem-solving measure: Further evaluation with maltreating and nonmaltreating parents

Inability to solve problems related to parenting and other aspects of daily living is hypothesized to result in frustration or inability to cope, and contribute to the occurrence of problematic parental behavior such as physical abuse or neglect. The present investigation evaluated the Parental Problem-Solving Measure (PPSM), a procedure for measuring parental problem-solving skill of maltreating and nonmaltreating parents. Subjects were 60 parents with at least one child between the ages of 2 and 12. Subjects belonged to one of three groups: (a) physically abusive and/or neglectful parents (n=27); (b) nonmaltreating clinic parents seeking help for child behavior problems (n=12); and (c) nonmaltreating, non-help-seeking community parents (n=21). Results demonstrated the interrater reliability, internal consistency, and temporal stability of the PPSM and its five subscales. Support is also provided for the convergent and discriminant validity of the measure.     

Impurities, adulterants and diluents of illicit heroin in Denmark (Jutland and Funen)

The contents of impurities, adulterants and diluents in 77 samples of illicit heroin were determined by a combination of high-performance liquid chromatography and gas chromatography. The origin of each sample was characterized by calculating the content of the opium alkaloids in relation to the heroin content. The routes of distribution were compared by determination of the contents of caffeine, procaine and sugars. The results were used as a "chemical fingerprint" of each sample. The results indicate that it is difficult to prove, with certainty, that two samples are identical. However, in most cases, by determining the amounts of impurities, adulterants and diluents in heroin samples, it will be possible to ascertain whether two samples are different and, in many cases, to determine with reasonable certainty whether two samples are identical.     

Regional Transboundary Cooperation Efforts in Centralist States: Conflicts and Responses in France and Mexico

France and Mexico have long traditions of highly centralizedgovernment. Nevertheless,in each case, populations in borderregions, which are distant from the national capital, have closeinformal cultural and economic ties with neighboring populationsin adjacent nations. In France, tensions between central authoritiesand local and regional authorities over greater internationalcooperation at the local and regional levels have been especiallyevident in Alsace, France's "window" on Europe's economic heartland.Administrative decentralization measures now being implementedin France will probably enhance transborder cooperation, thoughFrance still has not formally endorsed the European OutlineConvention on Transfrontier Cooperation. The Mexican governmentmaintains its historic resistance to dependency on the UnitedStates, and emphasizes policies to integrate its border citiesmore closely with the rest of Mexico. However, Mexico, likeFrance, could give greater attention to the development of internationalagreements that respect national sovereignty as well as thewishes of border peoples for closer transborder cooperation.     

Reviews

László Csaba, ed., Systemic Change and Stabilization in Eastern Europe. Aldershot, and Brookfield, NY: Dartmouth Publishing Co., 1991, x + 141 pp. £30.00.

Christopher T. Saunders, ed., Economics and Politics of Transition. New York: Macmillan Press, 1992, x + 419 pp., £50.00.

David Lane, Soviet Society under Perestroika, Completely revised edition. London and New York: Routledge, 1992, xvi + 441 pp., £15.99.

Judith B. Sedaitis & Jim Butterfield, eds, Perestroika from Below: Social Movements in The Soviet Union. Boulder, CO, San Francisco, CA, and Oxford: 1991, xii + 220 pp., $23.00 h/b.

Michael J. Sodaro, Moscow, Germany, and the West from Khrushchev to Gorbachev. London: I. B. Tauris, 1991, xiv + 423 pp., £29.95.

Örjan Sjöberg, Rural Change and Development in Albania. Boulder, CO, San Francisco, CA, and Oxford: Westview Press, 1991, xi + 199 pp., £21.95 p/b.

Anthony Kemp‐Welch, ed., The Ideas of Nikolai Bukharin. Oxford: Clarendon Press, 1992, 209 pp., £27.50.     

Lipids in the proximal tubules of the kidney in diabetic coma

Vacuolization of the renal tubular epithelial cells (the Armanni-Ebstein lesion) associated with diabetic hyperglycemia is usually regarded as an accumulation of glycogen. In a case of death of diabetic coma, the vacuoles were stained strongly for lipids. This observation may have both clinical and therapeutic consequences, and may increase our knowledge of the metabolism in diabetes.