Field-portable detection of fentanyl and its analogs: A review

The need to detect fentanyl and its analogs in the field is an important capability to help prevent unintentional exposure or overdose on these substances, which may result in death. Many portable methods historically used in the field by first responders and other field users to detect and identify other chemical substances, such as hazardous materials, have been applied to the detection and identification of these synthetic opioids. This paper describes field portable spectroscopic methods used for the detection and identification of fentanyl and its analogs. The methods described are automated colorimetric tests including lateral flow assays; vibrational spectroscopy (mid-infrared and Raman); gas chromatography–mass spectrometry; ion mobility spectrometry, and high-pressure mass spectrometry. In each case the background and key details of these technologies are outlined, followed by a discussion of the application of the technology in the field. Attention is paid to the analysis of complex mixtures and limits of detection, including the required spectral databases and algorithms used to interrogate these types of samples. There is also an emphasis on providing actionable information to the (likely) non-scientist operators of these instruments in the field.     

Forensic isoscapes based on intra-individual temporal variation of δ18O and 206Pb/207Pb in human teeth

Isotopic signatures used in the georeferencing of human remains are largely fixed by spatially distinct geologic and environmental processes. However, location-dependent temporal changes in these isotope ratios should also be considered when determining an individual’s provenance and/or trajectory. Distributions of the relevant isotopes can be impacted by predictable external factors such as climate change, delocalisation of food and water sources and changes in sources and uses of metals. Using Multi-Collector Inductively-Coupled Plasma Mass Spectrometer (MC-ICP-MS) analyses of ²⁰⁶Pb/²⁰⁷Pb in tooth enamel and dentin from a population of 21 ± 1-year-old individuals born circa 1984 and isotope ratio mass spectrometry (IRMS) of δ¹⁸O in their enamel, we examined the expected influence of some of these factors. The resulting adjustments to the geographic distribution of isotope ratios (isoscapes) found in tooth enamel and dentin may contain additional useful information for forensic identification, but the shifts in values can also impact the uncertainty and usefulness of identifications if they are not taken into account.

KEY POINTS

• Isoscapes of ²⁰⁶Pb/²⁰⁷Pb and δ¹⁸O used for geolocation are not static.
• Within a few years, the enamel and dentin of a person may exhibit measurable differences in ²⁰⁶Pb/²⁰⁷Pb even without changing locations.
• Changes in climatic patterns tied to rising temperatures are more significant than the direct effect of increasing temperature on δ¹⁸O fixed in tooth bioapatite.
• Third molar (M3) enamel mineralisation includes material incorporated from before formal amelogenesis takes place.

     

Distinctly Neoliberal: A Latent Profile Analysis of Neoliberal Ideology and Its Associations with Sociopolitical Actions and Sexual Attitudes

Social Justice Research - Scholars warn that neoliberalism erodes investment in the well-being of others by prizing the self-interested individual. To empirically investigate this claim, we...     

Opportunity for A Better World

The coronavirus crisis should make us appreciate our common humanity The novel coronavirus disease(COVID-19)is now a truly global crisis,which has spread from public health to the economy and governance.With more than 460,000infections reported globally as of March 26 and the fatalities rising its impact in Europe has been particularly hard.Italy,Spain and Germany have been profoundly affected.     

Fictional power and control and the reality of abusive behaviour

In response to recent sociological studies that suggest that the seriousness of psychological, emotional and verbal abuse are not only dismissed but are also the least identified in dating relationships, this article undertakes an analysis of these underexplored, ‘less visible’, elements using Ellen Pence and Michael Paymar’s ‘Power and Control’ and ‘Equality’ wheels, it compares Stephanie Meyer’s 10th anniversary re-release of Twilight, and Life and Death: Twilight Reimagined, which tells the same story as Twilight, but with the genders reversed are compared using the ‘Power and Control’ and ‘Equality’ wheels. The author argues that Life and Death is not just a simple swap of names and pronouns, as Meyer asserts, but that the alterations of thoughts and actions of the characters reflect commonly held ideas about gender, including the perpetration of psychological, emotional and verbal abuse in intimate relationships as hallmarks of masculinity. Moreover it shows that consistent with the feminisation of vampire Edythe Cullen and mortal Beau Swan, the intimate relationship in Life and Death more closely resembles that of a non-violent and equitable relationship, which significantly lessens the abuse, and reinforces traditionally socially accepted messages about gender in intimate relationships.     

Every Bag Counts

正Plastic. In these petroleum-based times, you can’t live with it, and you can’t live without it. Since this magical substance, with its plethora of manifestations, controls our city-dwelling lives to such a mas-sive degree, it pays to sit back and remember our day-to-day environmental responsibilities     

The Use of the Adult Attachment Scale with Domestically Violent Men

Empirical evidence highlights the utility of examining attachment styles in exploring the etiology of intimate partner violence perpetration, with insecure attachment styles regularly identified as underscoring domestically violent men. This study applied the 18-item self-report Adult Attachment Scale (Collins & Read, Journal of Personality and Social Psychology, 58(4), 644–663 1990) to 176 men entering a domestic violence perpetration counseling program. Factor analyses failed to result in the three factor model of the AAS. Subsequent item analyses indicated participants’ random and contradictory response style negated the possibility of any coherent factor structure. The results of this study caution investigators on the validity of self-report data with domestically violent men and offers both research and clinical/conceptual implications.