Interrogating genomic diversity of E. coli O157:H7 using DNA tiling arrays

Here, we describe a novel microarray-based approach for investigating the genomic diversity of Escherichia coli O157:H7 in a semi-high throughput manner using a high density, oligonucleotide-based microarray. This microarray, designed to detect polymorphisms at each of 60,000 base-pair (bp) positions within an E. coli genome, is composed of overlapping 29-mer oligonucleotides specific for 60 equally spaced, 1000-bp loci of the E. coli O157:H7 strain EDL933 chromosome. By use of a novel 12-well microarray that permitted the simultaneous investigation of 12 strains, the genomes of 44 individual isolates of E. coli O157:H7 were interrogated. These analyses revealed more than 150 single nucleotide polymorphisms (SNPs) and several deletions and amplifications in the test strains. Pyrosequencing was used to confirm the usefulness of the novel SNPs by determining their allelic frequency among a collection of diverse isolates of E. coli O157:H7. The tiling DNA microarray system would be useful for the tracking and identification of individual strains of E. coli O157:H7 needed for forensic investigations.     

It was not me: attribution of blame for criminal acts in psychiatric offenders

The current article addresses the psychometric qualities of the German Version of Gudjonsson's Blame Attribution Inventory (GBAI), a self-report scale for measuring attribution of blame for crime. The GBAI was administered to a criminal sample of forensic and criminal inmates (n=107). Findings indicate that the German version of the Gudjonsson Blame Attribution Inventory possesses acceptable test-retest stability and good internal consistency. Factor analysis reproduced the three basic dimensions of the GBAI: external attribution, mental-element attribution, and guilt-feeling attribution. Forensic patients had higher mental-element attribution and guilt-feeling attribution scores than the prison inmates. Interestingly, sexual offenders who were prisoners, showed the lowest guilt-feeling attribution, while sexual offenders who were forensic patients had the highest guilt-feeling attribution scores. Since earlier research reported a tendency of faking good in sexual offenders, we suggest that the forensic sexual offenders may demonstrate a social desirable response tendency in an attempt to gain sympathy and/or earlier parole. All in all, our data show that the German version of the GBAI is a valuable tool for measuring attributional styles of offenders.     

Judiciaries as crucial actors in Southern regulatory systems: A case study of Indian telecom regulation

This article addresses regulatory reforms in the Indian telecommunications sector and emphasizes the role of the Indian judiciary. Our claim is that when confronted with a series of disputes relating to the nascent telecom regulatory landscape, the Supreme Court of India sought to make a constructive contribution to both the actual disputes as well as the overall regulatory framework. Our reading of these cases suggests that in the sphere of telecom, the Supreme Court has been less interested in stamping its own authority on issues, and has instead sought to bolster the authority and legitimacy of the recently constituted telecom regulatory institutions. We seek to draw attention to the role of the Indian judiciary as marking an exceptional feature of evolving regulatory systems in the Global South. Conventional wisdom in the regulatory jurisprudence that has evolved in the Global North suggests that judiciaries should have little or no role to play in regulatory systems. We suggest that to overcome the special challenges that regulatory systems in the Global South confront, more established institutions and actors might have to lend credibility and legitimacy to enable nascent regulatory actors to develop over time. At least in the Indian case, this is one way to understand the Indian judiciary's interventionist actions in the sphere of telecom regulation.     

Prosocial Values and Performance Management Theory: Linking Perceived Social Impact and Performance Information Use

Performance management techniques are presented as control mechanisms to save money and hold bureaucrats accountable, consistent with negative agency theory assumptions of bureaucrats. We propose an alternative theory of performance management that rests on prosocial values. This theory argues that public servants who see the social impact of their work are more likely to use performance metrics. We operationalize performance information use in terms of purposeful use for internal organizational means, and political use for external legitimation. Those who perceive that their work has a strong social impact are likely to pursue both types of uses, to improve both the effectiveness of their services, and to maintain resources. The data come from a cross‐sectional survey of U.S. public and nonprofit employees.     

Imitating the West? Evidence on Administrative Reform from the Upper Echelons of Chinese Provincial Government

This article explores the attitudes of officials in the upper echelons in Chinese provincial and local government toward the origins of administrative reform. The authors examine the somewhat dichotomous argument that reform imitates the West or is indigenous and contend that both influences are present. Data drawn from a survey of party cadres and government officials show that cultural factors (time in government, overall knowledge of administrative reforms, together with familiarity with the move from a planned system of government to a market economy) and structural variables (upper echelon and familiarity with business management techniques) are correlated with learning from the West. Cadres and officials who spend more time managing outward and those who are familiar with performance assessment do not learn from the West. The theoretical and research implications of these findings—that learning from the West is an important influence on the adoption of administrative reforms in China—are discussed.     

The intellectual legacy of Gordon Tullock

Gordon Tullock is one of the world’s leading economists. Even more so than Chicago’s Gary Becker, Tullock has extended the rational choice model into areas previously judged to lie outside the realm of economics. This essay identifies Tullock’s contributions to constitutional political economy, public choice, bureaucracy, the law, and bio-economics. The essay focuses attention most especially on Tullock’s pioneering contributions to public choice, including his twenty-year editorship of Public Choice.     

The frontier revisited: displacement,land and identity among farm labourers in the Sundays River Valley

This paper aims to unpack the dynamics of displacement and the relationship of physical movement to elements of space (i.e. land) and place (or identity), in the Sundays River Valley, near the town of Kirkwood, in the Eastern Cape, South Africa. It primarily uses the motif of frontiers to cast light on displacement as an ongoing phenomenon and explore the different eras of occupation of land in the Sundays River Valley, from the early nineteenth century until 1970. It relates different layers of belonging and identity to the unfolding of capitalism and apartheid in South Africa. The article argues that ties to land are multiple, contested and based upon dispossession and physical movement rather than upon stability. While such a high degree of contestation of oral evidence in the Sundays River Valley might not give current claimants a detailed legal basis for restitution, it is an academically valuable idea to explore the origins of the inhabitants in the Sundays River Valley – because it can indicate the degree to which local identities are influenced by experiences of disruption and displacement. The paper argues that frontier relationships in the SRV are central in the formation of larger systems of relationships of race and class, and that this casts new light on displacement (both as a historical event and a contemporary experience), in the formation of identity and place in southern Africa.     

Histomorphological features of gunshot injuries to the calvarian bone in nephrogenic osteopathy

This histological study of calvarian bones with the injuries inflicted by a shot from an Osa traumatic non-lethal pistol revealed nephrogenic osteopathy in the preceding period. The pathologically altered bone tissue was damaged by a relatively mild tangential traumatic impact. It is concluded that the possibility of such pathological changes should be taken into consideration in the forensic medical expertise of any trauma including gunshot injuries.     

Sex estimation from the mastoid process among North Indians

Determination of sex from fragmentary crania is a critical problem in forensic anthropology. Osteometric analysis of mastoid can serve forensic anthropologists better in sex identification by virtue of the noticeable dimorphic characteristics. The present study aims to develop population-specific, sex-differentiating anthropometric standards for the mastoid process of North Indian skulls. Eight parameters of the mastoid region were measured on 138 adult crania (M/F 104:34, 22-65 years) and analyzed using SPSS 16.0. All parameters showed significant sexual dimorphism (p < 0.000). In stepwise analysis, asterion-mastoidale and mastoid breadth have provided an accuracy of 87%. Receiver operating characteristic curves were obtained for each variable to observe their overall performance in sex determination. Posterior end of incisura mastoidea-depression of suprameatal triangle was found to be the best variable with maximum area under curve and highest predictive accuracy (82.6%).