Organelle DNA haplotypes reflect crop-use characteristics and geographic origins of Cannabis sativa

Comparative sequencing of cannabis individuals across 12 chloroplast and mitochondrial DNA loci revealed 7 polymorphic sites, including 5 length variable regions and 2 single nucleotide polymorphisms. Simple PCR assays were developed to assay these polymorphisms, and organelle DNA haplotypes were obtained for 188 cannabis individuals from 76 separate populations, including drug-type, fibre-type and wild populations. The haplotype data were analysed using parsimony, UPGMA and neighbour joining methods. Three haplotype groups were recovered by each analysis method, and these groups are suggestive of the crop-use characteristics and geographical origin of the populations, although not strictly diagnostic. We discuss the relationship between our haplotype data and taxonomic opinions of cannabis, and the implications of organelle DNA haplotyping to forensic investigations of cannabis.     

Overview of: “Getting the Law Involved a Quasi-Experiment in Early Intervention Involving Collaboration Between Schools and the District Attorney's Office”

Research Summary Precursors to serious and chronic delinquency often emerge in childhood, stimulating calls for early interventions. Most intervention efforts rely solely on social service programs—often to the exclusion of the juvenile justice system. The juvenile justice system has been reluctant to become involved in the lives of relatively young children fearing net widening or further straining resources that could be used for older youth with documented delinquency histories. We report here the results of an early intervention program sponsored by and housed in a district attorney's office in Louisiana. Using a quasi-experimental design, we examined outcomes associated with program involvement as well as whether the obvious involvement of the prosecutor's office was associated with further reductions in problem behavior.

• 1 : The results revealed that significant reductions in problem behaviors of young children could be attributed to program participation.
• 2 : The obvious involvement of the district attorney's office, however, was associated with limited, albeit significant, reductions in specific problem behaviors.
• 3 : These findings show that successful early intervention efforts can be made part of the juvenile justice system and that in some limited situations prosecutorial involvement can result in positive outcomes.

Policy Implications The expansion of early intervention programming into the juvenile justice system offers opportunities to address early problem behavior. Our study and its results have the following policy implications.

• 1 : Closely coupled partnerships between schools and the juvenile justice system can effectively address, mitigate, and perhaps prevent an early onset of antisocial behavior.
• 2 : Even so, coupling early intervention efforts to the mission of the juvenile justice system warrants debate. Net-widening, resource diffusion, and the potential for officials to rely too heavily on the deterrent characteristics of the justice system represent serious threats to the integrity of effective early intervention programs.
• 3 : We suggest substantial debate and consideration is given before coupling early intervention efforts to the juvenile justice system.

     

Establishing forensic search methodologies and geophysical surveying for the detection of clandestine graves in coastal beach environments

A 2010 UK police search for a clandestine burial highlighted the need for more information and quantitative data to aid coastal beach searches. This study aimed to address this by establishing relevant forensic search methodologies to aid the search for clandestine coastal burial sites, using the North West English coastline as a search area. A set of parameters were established, including criteria such as tidal range, proximity to vehicular access points and distance from inhabited areas, which may inform forensic searches by prioritising likely locations of clandestine burials. Three prioritised coastal locations were subsequently identified: (1) coastal dunes at Formby, (2) coastal dunes and (3) beach foreshore at Southport, all sites part of the Liverpool City Region in the United Kingdom. At all locations, simulated clandestine graves were hand-dug by spades into which a naked adult-sized, metal-jointed fiberglass mannequin was buried at 0.5 m below ground level. Trial geophysical surveys were then undertaken with the aim of identifying the optimal geophysical instrumentation and technique to deploy in such environments. GPR data showed 450 MHz frequency antennae to be optimal, with significantly poor data obtained from the foreshore area due to saline seawater. Electrical resistivity and magnetic susceptibility surveys were successful in coastal environments in target detection (albeit not in non-vegetated sand dunes), with resistivity fixed-offset configurations deemed optimal. The latter survey successes may be due to the recent disturbed 'grave' rather than the target, which itself is of interest in terms of identifying the most recent clandestine burials.     

Correlates of Substantiated Emotional Maltreatment in the Second Canadian Incidence Study

The objective of this study was to determine the correlates of substantiated psychological maltreatment (PMT) in Canada on functions of maltreatment characteristics, child profile, household profile, and child protection services interventions. This study is based on a secondary analysis of data collected in the second Canadian Incidence Study. PMT investigations were categorized into six groups: emotional abuse, emotional neglect, and other maltreatment as single form, and these same three groups when they co-occurred with another form of maltreatment. Six logistic regressions, comparing all pairs of groups, were carried out. Cases of PMT (single form) were more chronic and associated with greater adverse emotional impact than other forms of maltreatment. Mothers of psychologically maltreated children had more mental health issues. Emotional neglect cases were more complex (e.g., substance abuse, mental health, and social housing). The three co-occurrent groups present more negative factors but more risk factors are observed when PMT are also observed (e.g., emotional harm, alcohol abuse, housing problems, chronicity, and referral to other services).     

The changing role of the Privy Council Office†

Abstract. Since the establishment of the office of Secretary to the Cabinet thirty years ago, there have been a number of changes in the way the cabinet operates, one being in the cabinet committee system which has passed through three distinct phases and is now in a fourth. Nine standing committees exist, with significant changes in procedure, permitting ministers to participate more fully in discussion and to share responsibility better. The Cabinet Committee on Priorities and Planning, established in 1968, deals with broad objectives, main questions of policy with long-term implications and with priorities for broad financial allocation. With the complexity of government and the scale of die elements of complexity increasing, the demands on ministerial time have become overwhelming. The Operations, Plans and Federal-Provincial Affairs Divisions of the Privy Council Office, with a small and discreet staff constantly changing to avoid the formation of a ruling elite, assist the prime minister, cabinet and cabinet committees in the total process of decision-making and in assuring a coherence of policy. Attempts are made to provide the central executive with full information and optimum freedom in taking the decisions for which parliament and the people of Canada have given them responsibility. Sommaire. Depuis la création du poste de secrétaire du Cabinet, il y a une trentaine d'années, il s'est produit un certain nombre de changements dans le fonctionnement même du cabinet. Citons, entre autres, le système des comités du cabinet qui est passé par trois phases distinctes et se trouve maintenant dans une quatrième phase. Il existe neuf comités permanents dont la procédure a subi d'importantes modifications pour permettre aux ministres de prendre une part plus active aux discussions, et de mieux partager les responsabilités. Le comité du cabinet chargé de l'établissement des priorités et de la planification, établi en 1968, s'occupe des objectifs généraux, des lignes de conduit A long terme et des priorités pour l'allocation générale des fonds. A cause de la complexité du gouvernement et de l'ampleur croissante de ses responsabilités, l'emploi du temps des ministres est devenu incroyablement chargé. Les sections des Opérations, des Plans et celle des Affaires fédérales-provinciales du Conseil privé, avec un personnel peu nombreux et discret, constamment renouvelé pour éviter la formation d'une élite trop influente, aident le premier ministre, le cabinet et les comités du cabinet à prendre les decisions qui s'imposent et à assurer la cohérence de la politique du gouvernementale. Elles s'efforcent de fournir à l'exécutif central toute information utile et de lui assurer le maximum de liberté pour prendre les décisions dmt l'ont chargé le parlement et le peuple canadien.     

Brexit and Strand Three of the 1998 Agreement: The Three Faces of East-West

Under Strand Three of the 1998 Belfast ‘Good Friday’ Agreement, institutions were set up to promote the ‘harmonious and mutually beneficial development’ of the ‘totality of relationships’ between the peoples and governments of Ireland and the UK, including its devolved administrations and Crown Dependencies. According to the text of the 1998 Agreement this ‘east-west’ dimension was to have two elements with corresponding institutions: an intergovernmental one reflected in the British-Irish Intergovernmental Conference (BIIC) and an interjurisdictional one reflected in the British-Irish Council (BIC). These Strand Three institutions were designed to provide fora for, respectively, intergovernmental cooperation on ‘non-devolved Northern Ireland matters’ in the case of the BIIC and information exchange and cooperation ‘on matters of mutual interest within the competence of the relevant Administrations’ in the case of the BIC. Nowhere in the 1998 Agreement text is the concept of ‘east-west’ used to refer to relations between Northern Ireland and Great Britain. Yet, in the wake of Brexit, and in the midst of controversy over the implications of the Protocol on Ireland / Northern Ireland, relations between Great Britain and Northern Ireland (GB–NI) have been newly framed as ‘east-west’. The creation of this new discursive face of ‘east-west’ relations marks an important, but little discussed, impact of Brexit on the political and constitutional landscape of the UK and Ireland. Against this backdrop, this article considers the impacts of Brexit, and the Protocol, on three faces of ‘east-west’ relations—the BIIC, the BIC and, newly, GB–NI—and discusses their implications for the future of Strand 3 institutions and the ‘totality of relationships’ they represent.     

Constituent Communication Through Telephone Town Halls: A Field Experiment Involving Members of Congress

Telephone town halls are an increasingly prevalent method for members of Congress (MCs) to communicate with constituents, even while garnering popular criticism for failing to facilitate engagement and accountability. Yet scholars have paid little attention to the events and their effects, and even less to how they might be improved. To remedy this problem, we report on a field experiment in which four MCs joined their constituents in telephone town halls. Overall, participation in an event improved constituents’ evaluations of the format in general, and of the MC in particular. Furthermore, we studied how these events might be improved by evaluating a reform—a single‐topic focus with predistributed briefing materials—designed to enhance deliberative interaction. This reform enhanced effects on opinions of the format without significantly altering effects on attitudes toward the MC. Our results suggest that telephone town halls hold promise for constituents, officeholders, and democratic practice.     

The Identity of Person and World in <Emphasis Type="Italic">Caraka Saṃhitā</Emphasis> 4.5

This paper examines the puru?a concept in the Caraka Sa?hitā (CS), an early text of Ayurveda, and its relation to Indic thinking about phenomenal worldhood. It argues that, contrary to the usual interpretation, early Ayurveda does not consider the person to be a microcosmic replication of the macrocosmos. Instead, early Ayurveda asserts that personhood is worldhood, and thus the person is non-different from the phenomenal totality (spatial and temporal) of his existence. This is confirmed by the CS’s several definitions of puru?a, which are alternately posed in terms familiar to Vai?e?ika, early (pre-“classical”) Sā?khya, early Buddhism, and Upani?adic monism. It is likewise confirmed by the Ayurvedic logic of sāmānya (translated as “identity”), which governs the meaning of the list of person-to-world correspondences in CS 4.5 and its often misinterpreted claim, puru?o’yam lokasa?mita?. Finally it is confirmed in the program of Ayurvedic therapeutics, which aims at establishing various kinds of “appropriateness” for the sake of effecting samayoga—the “harmonious joining” of person and world.